Why the missing heritability might not be in the DNA

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Bioessays 39 (7):1700067 (2017)
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Abstract

Graphical AbstractThere are four major hypotheses (H1, H2, H3, and H4) as to the source of missing heritability. We propose that estimates obtained from GWAS underestimate heritability by not taking into account non-DNA (epigenetic) sources of heritability. Taking those factors into account (H4) should result in increased heritability estimates.

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10.1002/bies.201700067

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Author Profiles

Eva Jablonka
Qiaoying Lu
Peking University
Pierrick Bourrat
Macquarie University

Citations of this work

Dissolving the Missing Heritability Problem.Pierrick Bourrat & Qiaoying Lu - 2017 - Philosophy of Science 84 (5):1055-1067.
Unifying heritability in evolutionary theory.Pierrick Bourrat - 2022 - Studies in History and Philosophy of Science Part A 91 (C):201-210.

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The Evolutionary Gene and the Extended Evolutionary Synthesis.Qiaoying Lu & Pierrick Bourrat - 2017 - British Journal for the Philosophy of Science 69 (3):775-800.

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