Explanation of Molecular Processes without Tracking Mechanism Operation

Philosophy of Science 85 (5):984-997 (2018)
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Abstract

Philosophical discussions of systems biology have enriched the notion of mechanistic explanation by pointing to the role of mathematical modeling. However, such accounts still focus on explanation in terms of tracking a mechanism's operation across time (by means of mental or computational simulation). My contention is that there are explanations of molecular systems where the explanatory understanding does not consist in tracking a mechanism's operation and productive continuity. I make this case by a discussion of bifurcation analysis in dynamical systems, articulating the distinctive way in which explanatory understanding is provided, especially about the reversibility or irreversibility of molecular processes.

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Ingo Brigandt
University of Alberta

Citations of this work

Multiple Realization in Systems Biology.Wei Fang - 2020 - Philosophy of Science 87 (4):663-684.
Design principles as minimal models.Wei Fang - 2024 - Studies in History and Philosophy of Science Part A 105 (C):50-58.

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References found in this work

Explanation: a mechanist alternative.William Bechtel & Adele Abrahamsen - 2005 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 36 (2):421-441.
Abstraction and the Organization of Mechanisms.Arnon Levy & William Bechtel - 2013 - Philosophy of Science 80 (2):241-261.
Mechanism and Biological Explanation.William Bechtel - 2011 - Philosophy of Science 78 (4):533-557.

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