This article describes and analyzes the design and functioning of the Statistical Ethics System (SETE) in Colombia’s National Statistical Office. It presents the methodology and general process of planning and implementation of the System, supported by a conceptual analysis of the requirements for an ethical functioning of official statistics. The general objective of the article is to make a practical contribution to the understanding of conceptual and practical features that ought to be considered in the implementation of an ethical system (...) in the operation of the public sector, particularly in the area of the production of official statistics. The text is divided into five parts. In the first part, we make a general introduction to the ethical value of official statistics. In the second and third parts, we make a presentation and analysis of the principles and risks that were selected as the basic ethical framework for the production of official statistics at the National Administrative Department of Statistics (DANE). The fourth section presents the conceptual and practical bases of how SETE operates. The fifth section we present some concluding remarks. (shrink)

Este artículo propone reconsiderar, en el marco de la filosofía política, el enfoque tradicional del problema del deber moral de obedecer al Estado. Se postula la relevancia de atender las objeciones del anarquismo filosófico en contra de tal deber, partiendo de algunas críticas esbozadas por R.P. Wolff y J. A. Simmons; dos de los representantes más significativos de esta rama de la filosofía en tiempos contemporáneos. Siguiendo esta línea argumental, se afirma la inexistencia del deber moral de obedecer al Estado, (...) abogando así por una posición crítica respecto de la autoridad, sin llegar a la conclusión del anarquismo político, según la cual existe la obligación de abolir o combatir la autoridad política. Así, se propone que la pregunta por la legitimidad del Estado solo puede abordarse casuísticamente, desde un análisis de ética aplicada sobre las diferentes imposiciones de la autoridad. (shrink)

The study of cellular senescence and proliferative lifespan is becoming increasingly important because of the promises of autologous cell therapy, the need for model systems for tissue disease and the implication of senescent cell phenotypes in organismal disease states such as sarcopenia, diabetes and various cancers, among others. Here, we explain the concepts of proliferative cellular lifespan and cellular senescence, and we present factors that have been shown to mediate cellular lifespan positively or negatively. We review much recent literature and (...) present potential molecular mechanisms by which lifespan mediation occurs, drawing from the fields of telomere biology, metabolism, NAD+ and sirtuin biology, growth factor signaling and oxygen and antioxidants. We conclude that cellular lifespan and senescence are complex concepts that are governed by multiple independent and interdependent pathways, and that greater understanding of these pathways, their interactions and their convergence upon specific cellular phenotypes may lead to viable therapies for tissue regeneration and treatment of age‐related pathologies, which are caused by or exacerbated by senescent cells in vivo. (shrink)

RESUMENEl desarrollo embriológico es un fenómeno que ha inspirado la especulación filosófica desde temprano en la historia del pensamiento. Desde los tiempos de Aristóteles dos modelos conceptuales antitéticos se han utilizado tradicionalmente para comprender la embriogénesis: o el embrión posee ya una forma o estructura, o ésta se forma de nuevo en cada generación. Nuestro objetivo en este artículo es mostrar que el contraste entre la posición preformacionista y epigenética persiste a pesar de los formidables avances teóricos y experimentales de (...) la biología del desarrollo contemporánea. El preformacionismo y la epigénesis han perfeccionado constantemente sus posiciones en el curso de la historia con el fin de responder a los retos conceptuales de la época. Este continuo proceso de transformación ha dado lugar a una convergencia parcial entre las dos posiciones. Sin embargo, vamos a argumentar que, a pesar de los esfuerzos por conciliar ambas posturas, esta antinomia, que se erige como una de las más fundamentales de la biología, no será fácil de superar. ABSTRACTThe process of development of the embryo has inspired philosophical speculation since the advent of Western thought. Since the time of Aristotle two antithetical conceptual models have traditionally been used to understand embryogenesis: either form or structure is preformed in the embryo or it is newly formed with each generation. Our aim in this article is to show that the contrast between the pre-formationist and epigenetic positions persists despite the formidable theoretical and experimental advances of contemporary developmental biology. Pre-formationism and epigenesis have constantly refined their positions in the course of history in order to answer the conceptual challenges of each epoch. This process of continuous transformation has resulted in a partial convergence of the two positions. However, we shall argue that, despite the partial successes of this process of continuous convergence, one of the most fundamental antinomies in biology persists. (shrink)

David Hernández Castro ABSTRACT: Scholars have generally analysed Empedocles’ criticism of sacrifices through a Pythagorean interpretation context. However, Empedocles’ doctrinal affiliation with this school is problematic and also not needed to explain his rejection of the ‘unspeakable slaughter of bulls.’ His position is consistent with the wisdom tradition that emanated from the Sanctuary of Apollo ….

Durante la transición del siglo VI al siglo V a.C. la Magna Grecia experimentó grandes transformaciones sociales y políticas. El ascenso de la tiranía y los primeros avances democráticos produjeron una erosión del poder de la aristocracia y la consagración del Santuario de Delfos como la principal fuente de legitimidad de esta nueva centralidad política. El caso de Metaponto nos ofrece una oportunidad privilegiada para observar este proceso, ya que disponemos de varias fuentes, incluido un relato de Heródoto, que nos (...) permiten acceder a la forma en la que el culto délfico cristalizó entre los metapontinos. La máxima expresión de este culto fue el temenos de Apolo y Aristeas, del que se ofrece una interpretación en este artículo, completada por la posible identificación de una base que habría formado parte del conjunto monumental y estaría representada en el registro numismático. Esta base se encuentra actualmente en las instalaciones del Parco Archeologico dell’area urbana di Metaponto. (shrink)

A principios de los años ochenta, Michel Foucault impartió unas lecciones sobre la «παρρησία» en el Collège de France. Las lecciones de Foucault se convirtieron en una importante nueva interpretación de la noción de parresía. Básicamente, Foucault distingue entre una _parresía_ política de naturaleza democrática y una _parresía_ filosófica cuyo origen podría ser trazado hasta Platón. En este artículo concentro mi análisis en la _parresía _política, e intento demostrar que la definición de Foucault de este concepto no se corresponde con (...) el pensamiento democrático de la antigua Atenas. Según Foucault, la parresía es «une parole d’au-dessus», una palabra de arriba. Sin embargo, una interpretación alternativa de las fuentes antiguas puede demostrar que en realidad la _parresía _es una palabra de _abajo_. Al contrario de lo que sostiene Foucault, las obras de Eurípides, Demóstenes, Isócrates y otros autores contribuyen a encontrar una raíz popular en la _parresía_, que debería ser definida como la dignidad de la palabra del pueblo. (shrink)

Desde principios del siglo XX, muchos autores han intentado relacionar el origen del pensamiento griego con las transformaciones sociales o políticas que se produjeron con la irrupción de la polis antigua. Cornford veía una proyección de la estructura del comportamiento social, Jaeger, una analogía, y Vernant, una analogía de estructura del proceso de geometrización del espacio urbano. En este artículo, abordaré los problemas de analizar esta relación bajo el concepto de analogía, y propondré un enfoque alternativo basado en la distinción (...) entre los conceptos de espacio y lugar defendida por el filósofo australiano Jeff Malpas. Mi propuesta se complementa con algunos aspectos relacionados con la antropología comparada de Marcel Detienne, y se traduce en una metodología de investigación que propone abordar el problema del inicio de la sabiduría a través del concepto de matrices de pensamiento. (shrink)

El presente artículo trata los elementos órficos que pueden encontrarse en las Dionisíacas de Nono, un poema épico griego de época imperial (s.V). En su canto sexto podemos leer una versión del nacimiento y muerte de Dioniso Zagreo, un mito fundamental para la religión mistérica griega, tanto la órfica como la dionisíaca. Este artículo analiza el mito tal y corno lo encontramos en las Dionisíacas tratando de confrontarlo con lo que sabemos de la religión órfica y dionisíaca, todo ello desde (...) la óptica de Nono, un poeta entre paganismo y cristianismo, cuyas inclinaciones religiosas aún no han sido despejadas. (shrink)

This paper focuses on the religious background of lawgiving and its mythical models in books I-IV of the Laws. This latest of Plato's Works deals with the main tasks of a legislator in the ideal political community. In this dialogue, the lawgiver is the heir of a long Greek tradition with mythical and historical forerunners who had a special relation with the divinity. Perhaps the best example of this kind of divine lawgiver is Minos, who was able of knowing the (...) Gods' will and received from them the holy laws. In that aspect, Plato depends on the legendary nomothetai from myth and dwells heavily in oracular procedures as a way of communication with divinity and acquisition of decrees or confirmation of laws. If our view is correct, the model for the best possible constitution comes from Divine Wisdom through oracular mediation from their mythical origins in Crete and Egypt. The medium between Gods and Men and its mantic practices – as the holy men from myth and archaic Greek politics – seems a key figure for a better understanding of Plato's most complex dialogue. (shrink)

Biologists and philosophers often use the language of determination in order to describe the nature of developmental phenomena. Accounts in terms of determination have often been reductionist. One common idea is that DNA is supposed to play a special explanatory role in developmental explanations, namely, that DNA is a developmental determinant. In this article we try to make sense of determination claims in developmental biology. Adopting a manipulationist approach, we shall first argue that the notion of developmental determinant is causal. (...) We suggest that two different theses concerning developmental determination can be articulated: determination of occurrence and structural determination. We shall argue that, while the first thesis is problematic, the second, opportunely qualified, is feasible. Finally, we shall argue that an analysis of biological causation in terms of determination cannot account for entangled dynamics. Characterising causal entanglement as a particular kind of interactive causation whereby difference-making causes ascribable to different levels of biological organisation influence a particular ontogenetic outcome, we shall, via two illustrative examples, diagnose some potential limits of a reductionist, molecular and intra-level understanding of biological causation. (shrink)

Certain characteristics of childhood immaturity (e.g., infantile facial features) may have been favored by natural selection to evoke positive feelings in adults. We propose that some aspects of cognitive immaturity might also endear young children to adults. In two studies, adults rated expressions of mature and immature thinking attributed to children. Immature thinking in which children expressed a supernatural explanation elicited positive affect reactions, whereas other forms of immature thinking, which made no attribution to supernatural causation, were responded to negatively. (...) This pattern was found for parents and others, males and females, American and Spanish college students, and for target children 3 to 9 years of age. We suggest that persistence of supernatural thinking in adulthood causes people to view the expressions of such thinking in children in a positive manner, fostering nurturance of young children who display them. (shrink)

Although we find many merits to Grossmann's fearful ape hypothesis, unlike Grossmann, we see heightened fearfulness as an ontogenetic adaptation, signaling helplessness and fostering caregiving during infancy, which subsequently became exapted to promote cooperation. We also argue that, rather than being the “breeding ground” for enhanced infant fearfulness, cooperative care is more likely the evolved product of enhanced fearfulness.

A key aim in biology and psychology is to identify fundamental principles underpinning the behavior of animals, including humans. Analyses of human language and the behavior of a range of non-human animal species have provided evidence for a common pattern underlying diverse behavioral phenomena: Words follow Zipf's law of brevity (the tendency of more frequently used words to be shorter), and conformity to this general pattern has been seen in the behavior of a number of other animals. It has been (...) argued that the presence of this law is a sign of efficient coding in the information theoretic sense. However, no strong direct connection has been demonstrated between the law and compression, the information theoretic principle of minimizing the expected length of a code. Here, we show that minimizing the expected code length implies that the length of a word cannot increase as its frequency increases. Furthermore, we show that the mean code length or duration is significantly small in human language, and also in the behavior of other species in all cases where agreement with the law of brevity has been found. We argue that compression is a general principle of animal behavior that reflects selection for efficiency of coding. (shrink)

Measuring neuronal activity with electrophysiological methods may be useful in detecting neurological dysfunctions, such as mild traumatic brain injury (mTBI). This approach may be particularly valuable for rapid detection in at-risk populations including military service members and athletes. Electrophysiological methods, such as quantitative electroencephalography (qEEG) and recording event-related potentials (ERPs) may be promising; however, the field is nascent and significant controversy exists on the efficacy and accuracy of the approaches as diagnostic tools. For example, the specific measures derived from an (...) electroencephalogram (EEG) that are most suitable as markers of dysfunction have not been clearly established. A study was conducted to summarize and evaluate the statistical rigor of evidence on the overall utility of qEEG as an mTBI detection tool. The analysis evaluated qEEG measures/parameters that may be most suitable as fieldable diagnostic tools, identified other types of EEG measures and analysis methods of promise, recommended specific measures and analysis methods for further development as mTBI detection tools, identified research gaps in the field, and recommended future research and development thrust areas. The qEEG study group formed the following conclusions: 1. Individual qEEG measures provide limited diagnostic utility for mTBI. However, many measures can be important features of qEEG discriminant functions, which do show significant promise as mTBI detection tools. 2. ERPs offer utility in mTBI detection. In fact, evidence indicates that ERPs can identify abnormalities in cases where EEGs alone are nondisclosing. 3. The standard mathematical procedures used in the characterization of mTBI EEGs should be expanded to incorporate newer methods of analysis including nonlinear dynamical analysis, complexity measures, analysis of causal interactions, graph theory and information dynamics. 4. and 5. are too long to include here. (shrink)

This article explores how historical narratives affect the evaluation of political decisions regarding justice during peace negotiations. Specifically, this study evaluates how different narratives of the Colombian armed conflict relate to the preference for either restorative or retributive justice. Results revealed that a historically accurate narrative that included structural elements correlated with the preference for restorative justice, whereas a schematic narrative that focused on individual greed favoured the preference for retributive justice. These results are explained in terms of the characteristics (...) of expert historical narratives, which include structural elements, such as economic and institutional factors. The presence of these elements in the explanation of conflicts decreases the weight of individual decisions and, in this way, prevent ingroup attributional biases. (shrink)

El objetivo de esta investigación se centra en observar los eventos organizados por las empresas más responsables según el ranking MERCO, teniendo en cuenta si cumplen con las características de sostenibilidad definidas por la ISO 20121 sobre sistemas de gestión de sostenibilidad de eventos, que son: inclusividad, integridad, responsabilidad y transparencia. Para ello se analizarán todos los eventos, prestando especial atención a aquellos específicamente considerados como sostenibles. Los resultados muestran que menos de la mitad siguen criterios de sostenibilidad en su (...) realización. Llama la atención que la Norma ISO 20121 es de escasa aplicación en las organizaciones más responsables de España. (shrink)

Animals, including humans, are usually judged on what they could become, rather than what they are. Many physical and cognitive abilities in the ‘animal kingdom’ are only acquired (to a given degree) when the subject reaches a certain stage of development, which can be accelerated or spoilt depending on how the environment, training or education is. The term ‘potential ability’ usually refers to how quick and likely the process of attaining the ability is. In principle, things should not be different (...) for the ‘machine kingdom’. While machines can be characterised by a set of cognitive abilities, and measuring them is already a big challenge, known as ‘universal psychometrics’, a more informative, and yet more challenging, goal would be to also determine the potential cognitive abilities of a machine. In this paper we investigate the notion of potential cognitive ability for machines, focussing especially on universality and intelligence. We consider several machine characterisations (non-interactive and interactive) and give definitions for each case, considering permanent and temporal potentials. From these definitions, we analyse the relation between some potential abilities, we bring out the dependency on the environment distribution and we suggest some ideas about how potential abilities can be measured. Finally, we also analyse the potential of environments at different levels and briefly discuss whether machines should be designed to be intelligent or potentially intelligent. (shrink)

In this article we focus on the emergence of biological individuality by association, trying to formulate some theoretical conditions to think about the process of collective individualization. The starting point of our analysis is the notion of “major evolutionary transition.” A major evolutionary transition is the result of the integration of a multiplicity of initially independent biological entities that, by managing to organize their interactions, become a collective of components having an identity oriented towards a common goal. When biological organisms (...) are concerned, a major transition corresponds to a phenomenon of fusion between them. We shall argue that the emergence of a new biological level of individuality implies the establishment of constitutive relationships between individuals that change their status as autonomous entities. As a result, the emergence of a new type of entity in the living world implies that individuals enter into relationships that intrinsically transform them, a transformation sufficient for a “whole” to become a “part” that forms another “whole”, that is, a new level of organismality. (shrink)

In this article we focus on the emergence of biological individuality by association, trying to formulate some theoretical conditions to think about the process of collective individualization. The starting point of our analysis is the notion of “major evolutionary transition.” A major evolutionary transition is the result of the integration of a multiplicity of initially independent biological entities that, by managing to organize their interactions, become a collective of components having an identity oriented towards a common goal. When biological organisms (...) are concerned, a major transition corresponds to a phenomenon of fusion between them. We shall argue that the emergence of a new biological level of individuality implies the establishment of constitutive relationships between individuals that change their status as autonomous entities. As a result, the emergence of a new type of entity in the living world implies that individuals enter into relationships that intrinsically transform them, a transformation sufficient for a “whole” to become a “part” that forms another “whole”, that is, a new level of organismality. (shrink)

En este trabajo se propone una aproximación al uso filosófico del dios griego Dioniso en la obra de Platón, con especial referencia a la vertiente pedagógicopolítica del pensamiento platónico en la República y, sobre todo, en las Leyes. se discuten brevemente los trabajos anteriores que han tratado esta cuestión, incluidos los dos más recientes que versan sobre las Leyes y sobre la faceta filosófica de Dioniso, al hilo de una propuesta de lectura de las presencias y ausencias de Dioniso en (...) Platón a través de tres dimensiones −el simposio, los misterios y la poesía con fines educativos− que convergen en la finalidad política reformista del filósofo ateniense. (shrink)

La batalla del Ebro enfrento, durante 115 días personas y máquinas. Se experimentaron nuevas técnicas y tecnologías que jugarían un papel determinante en el inminente conflicto mundial. La aviación se utilizó, por primera vez, de manera masiva y su actuación fue decisiva. Sin embargo, su rastro patrimonial y es escaso. Al entorno de la guerra aérea en la Batalla del Ebro el presente trabajo plantea una experiencia de investigación transversal y holística que plantea la socialización didáctica del conocimiento histórico y (...) arqueológico a partir de propuestas metodológicas museográficas, de iconografía didáctica y de recuperación de la memoria histórica. El objetivo de esta acción combinada es generar y socializar conocimiento científico sobre el pasado y su legado material, incidir en la formación de una ciudadanía crítica y fomentar el desarrollo económico sostenible en base a la acción de industrias culturales relacionadas con el patrimonio. (shrink)

Scholars have generally analysed Empedocles’ criticism of sacrifices through a Pythagorean interpretation context. However, Empedocles’ doctrinal affiliation with this school is problematic and also not needed to explain his rejection of the ‘unspeakable slaughter of bulls.’ His position is consistent with the wisdom tradition that emanated from the Sanctuary of Apollo in Delphi, an institution that underwent significant political and religious changes at the end of the 6th Century B.C., the impact of which was felt all over Magna Graecia. The (...) ritual practice of sacrifice played an important role in Delphi, but the sanctuary also gave birth to a school of wisdom that was highly critical of the arrogance (hybris) of large sacrifices. Asocio-cultural analysis of the Akragas of the first half of the 5th Century B.C. provides new arguments that support this interpretation. The work of Empedocles contains more evidence of being influenced by the Delphi school of wisdom than by Orphism or Pythagoreanism. (shrink)

The aim of this study was to explore the role of voices as cues to adults of children’s needs for potential caregiving during early childhood. To this purpose, 74 college students listened to pairs of 5-year-old versus 10-year-old children verbalizing neutral-content sentences and indicated which voice was better associated with each of 14 traits, potentially meaningful in interactions between young children and adults. Results indicated that children with immature voices were perceived more positively and as being more helpless than children (...) with mature voices. Children’s voices, regardless of the content of speech, seem to be a powerful source of information about children’s need for caregiving for parents and others during the first six years of life. (shrink)

We performed a critical review of the historiographical studies on biogeography. We began with the pioneering works of Augustin and Alphonse de Candolle. Then, we analyzed the historical accounts of biogeography developed by (1) Martin Fichman and his history on the extensionism-permanentism debate; (2) Gareth Nelson and his critique of the Neo-Darwinian historiography of biogeography; (3) Ernst Mayr, with his dispersalist viewpoint; (4) Alan Richardson, who wrote a microhistory on the biogeographic model constructed by Darwin; (5) Michael Paul Kinch and (...) the ideas discussed in the 19th century about the geographical distribution of living beings; (6) Janet Browne, who highlighted the importance of the pre-Darwinian naturalists; (7) Peter Bowler, who focused mainly on the influence of paleontology on biogeography; (8) James Larson, who looked into the practices of the naturalists of Northern Europe in the late 18th century; and (9) Malte Ebach, who like Larson, was more interested in analysing the practices rather than the ideas of naturalists who studied the geographical distribution of organisms. Finally, these works are compared with each other. There has not been a dominant paradigm in the construction of historical narratives of biogeography; however, they provide a useful context for understanding problems of biogeography that continue to be debated to this day. (shrink)