Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Analytic philosophy has recently demonstrated a revived interest in metaphysical problems about possibility and necessity. Graeme Forbes here provides a careful description of the logical background of recent work in this area for those who may be unfamiliar with it, moving on to d discuss the distinction between modality de re and modality de dicto and the ontological commitments of possible worlds semantics. In addition, Forbes offers a unified theory of the essential properties of sets, organisms, artefacts, substances, and (...) events, based on the doctrine that identity facts must be intrinsically grounded, and analyzes and rejects apparent counterexamples to this doctrine. (shrink)

This paper is about a substitution-failure in attitude ascriptions, but not the one you think. A standard view about the semantic shape of ‘that’-clause attitude ascriptions is that they are fundamentally relational. The attitude verb expresses a binary relation whose extension, if not empty, is a collection of pairs each of which consists in an individual and a proposition, while the ‘that’-clause is a term for a proposition. One interesting problem this view faces is that, within the scope of many (...) attitude verbs, ‘that’-clauses are not interchange able with certain other terms which stand for the same propositions as the clauses are supposed to. For example, (1a) below may be true, but (1c) is probably not: (1) a. Holmes {fears/suspects} that Moriarty has returned. b. That Moriarty has returned is the proposition that Moriarty has re turned. c. Holmes {fears/suspects} the proposition that Moriarty has returned. For only the exceptionally timorous fear propositions, and, excluding contexts in which we speak of a ‘suspect premise’, only the unusually paranoid suspect them. The truth-conditional change eVected by substituting propositional descrip tion for ‘that’- clause illustrated in (1) occurs with a wide range of attitude verbs. If you understand that the window of opportunity is closing, perhaps you should act before it is too late, but if you mere-. (shrink)

Ableist attitudes and structures regarding disability are increasingly recognized across all sectors of healthcare delivery. After Dobbs, novel questions arose in the USA concerning how to protect reproductive autonomy while avoiding discrimination against and devaluation of disabled persons. As a case study, we examine the Louisiana’s Department of Public Health August 1st Emergency Declaration, “List of Conditions that shall deem an Unborn Child ‘Medically Futile.’” We raise a number of medical, ethical, and public health concerns that lead us to argue (...) the declaration should be rescinded. The ethically objectionable declaration provides valuable lessons concerning how to uphold both reproductive and disability justice in a post-Dobbs landscape. (shrink)

This volume provides an exposition of the key concept of avidya maya as set forth by advaitins and as criticized by Visistadvaitins. the philosophical conflicts ...

On the life and philosophy of Ramana Maharshi and his views on Advaita and epistemology.

In this particularly well written volume Graeme Hirst presents a theoretically motivated foundation for semantic interpretation (conceptual analysis) by computer, and shows how this framework facilitates the resolution of both lexical and syntactic ambiguities.

The Enlightenment and its legacy are still actively debated, with the Enlightenment acting as a key organizing concept in philosophy, social theory and the history of ideas. Counter-Enlightenments is the first full-length study to deal with the history and development of the Counter-Enlightenment thought from its inception in the eighteenth century right through to the present. Engaging in a critical dialogue with Isiah Berlin's work, this book analyses the concept of Counter-Enlightenment and some of the most important conceptual issues and (...) problems it raises. Graeme Garrard explores the diverse forms of Counter-Enlightenment thought, with a wide-ranging review of the principle figures of the past two hundred and fifty years, and he assesses the persuasiveness of the most common and important criticisms of the Enlightenment. (shrink)

From Detroit Red to El-Hajj Malik El-Shabazz, the man best known as Malcolm X restlessly redefined himself throughout a controversial life. His transformations have appeared repeatedly in books, photographs, paintings, and films, while his murder set in motion a series of tugs-of-war among journalists, biographers, artists, and his ideological champions over the interpretation of his cultural meaning. This book marks the first systematic examination of the images generated by this iconic cultural figure--images readily found on everything from T-shirts and hip-hop (...) album covers to coffee mugs. Graeme Abernethy captures both the multiplicity and global import of a person who has been framed as both villain and hero, cast by mainstream media during his lifetime as "the most feared man in American history," and elevated at his death as a heroic emblem of African American identity. As Abernethy shows, the resulting iconography of Malcolm X has shifted as profoundly as the American racial landscape itself. Abernethy explores Malcolm's visual prominence in the eras of civil rights, Black Power, and hip-hop. He analyzes this enigmatic figure's representation across a variety of media from 1960s magazines to urban murals, tracking the evolution of Malcolm's iconography from his autobiography and its radical milieu through the appearance of Spike Lee's 1992 biopic and beyond. Its remarkable gallery of illustrations includes reproductions of iconic photographs by Richard Avedon, Eve Arnold, Gordon Parks, Henri Cartier-Bresson, and John Launois. Abernethy reveals that Malcolm X himself was keenly aware of the power of imagery to redefine identity and worked tirelessly to shape how he was represented to the public. His theoretical grasp of what he termed "the science of imagery" enabled him both to analyze the role of representation in ideological control as well as to exploit his own image in the interests of black empowerment. This provocative work marks a startling shift from the biographical focus that has dominated Malcolm X studies, providing an up-to-date--and comprehensively illustrated--account of Malcolm's cultural afterlife, and addressing his iconography in relation to images of other major African American figures, including Martin Luther King, Jr., Angela Davis, Kanye West, and Barack Obama. Analyzing the competing interpretations behind so many images, Abernethy reveals what our lasting obsession with Malcolm X says about American culture over the last five decades. (shrink)

In this essay, we suggest practical ways to shift the framing of crisis standards of care toward disability justice. We elaborate on the vision statement provided in the 2010 Institute of Medicine (National Academy of Medicine) “Summary of Guidance for Establishing Crisis Standards of Care for Use in Disaster Situations,” which emphasizes fairness; equitable processes; community and provider engagement, education, and communication; and the rule of law. We argue that interpreting these elements through disability justice entails a commitment to both (...) distributive and recognitive justice. The disability rights movement's demand “Nothing about us, without us” requires substantive inclusion of disabled people in decision‐making related to their interests, including in crisis planning before, during, and after a pandemic like Covid‐19. (shrink)

Over recent decades there has been a growing interest in the question of whether computer programs are capable of genuinely creative activity. Although this notion can be explored as a purely philosophical debate, an alternative perspective is to consider what aspects of the behaviour of a program might be noted or measured in order to arrive at an empirically supported judgement that creativity has occurred. We sketch out, in general abstract terms, what goes on when a potentially creative program is (...) constructed and run, and list some of the relationships (for example, between input and output) which might contribute to a decision about creativity. Specifically, we list a number of criteria which might indicate interesting properties of a program’s behaviour, from the perspective of possible creativity. We go on to review some ways in which these criteria have been applied to actual implementations, and some possible improvements to this way of assessing creativity. (shrink)

The talk is called ‘The QUANTUM COMPLEXITY behind Quantum Reality’. It is divided into 3 parts: an outline of the essentials of quantum theory, a discussion of some glaring problems of interpretation, and my shocking philosophical conclusions.

We analyse aspects of the Big Bang program in modern cosmology, with special focus on the strategies employed by its adherents both in defending the theory against anomalous data and in dismissing rival accounts. We illustrate this by critically examining four aspects of Big Bang cosmology: the interpretation of the cosmic red-shift, the explanation of the cosmic background radiation, the inflation hypothesis and the search for dark matter. We conclude that the Big Bang's dominance of contemporary cosmology is not justified (...) by the degree of experimental support it receives relative to rival theories. (shrink)

Working memory limits are best defined in terms of the complexity of the relations that can be processed in parallel. Complexity is defined as the number of related dimensions or sources of variation. A unary relation has one argument and one source of variation; its argument can be instantiated in only one way at a time. A binary relation has two arguments, two sources of variation, and two instantiations, and so on. Dimensionality is related to the number of chunks, because (...) both attributes on dimensions and chunks are independent units of information of arbitrary size. Studies of working memory limits suggest that there is a soft limit corresponding to the parallel processing of one quaternary relation. More complex concepts are processed by or In segmentation, tasks are broken into components that do not exceed processing capacity and can be processed serially. In conceptual chunking, representations are to reduce their dimensionality and hence their processing load, but at the cost of making some relational information inaccessible. Neural net models of relational representations show that relations with more arguments have a higher computational cost that coincides with experimental findings on higher processing loads in humans. Relational complexity is related to processing load in reasoning and sentence comprehension and can distinguish between the capacities of higher species. The complexity of relations processed by children increases with age. Implications for neural net models and theories of cognition and cognitive development are discussed. (shrink)

This article examines nanotechnology within the context of the public interest. It notes that though nanotechnology research and development investment totalled US$9.6 billion in 2005, the public presently understands neither the implications nor how it might be best governed. The article maps a range of nanotechnology dialogue activities under way within the United Kingdom, the United States, Germany, and Australia. It explores the various approaches to articulating public interest matters and notes a shift in the way in which these governments, (...) on the whole, appear to be attempting to manage nanotechnology “risks.” It argues that open and transparent policy deliberations and extensive public discourse will be pivotal to protecting the public interest, gaining public trust and acceptance of nanotechnologies. The article concludes that though governing emerging technologies in the public interest is not a new concept, nanotechnology does present additional challenges that must be addressed by the guardians of the public interest. (shrink)

"Graeme Nicholson addresses the fundamental topic of ontology, perhaps the fundamental topic posed to philosophy and the human mind: what is being?, i.e., what is it to exist or to be? He initially shows that we humans must be understood to be "existers" and "disclosers"--terms that render Heidegger's concept Dasein. Heidegger's philosophy provides the basic viewpoint, but Professor Nicholson offers an interpretation of Heidegger that seeks to set deconstructionist and pragmatist readings to one side. Since, according to Heidegger, being (...) is fundamentally a union of presence and absence, this study shows that metaphysical theories have always offered positive illustrations or interpretations of being." "Illustrations of Being then goes on to scrutinize the four most fundamental determinations of being that Western thought has adumbrated: being as substance, especially in Greek ontology; being as reality, especially in the period from Descartes to Kant, and therefore in nineteenth- and twentieth-century science; the logic of being, in which Nicholson undertakes an ontological critique of mathematical logic; and being as the transformation of form--the key idea that runs from Christian patristics, through Hegel and Marx, to modern dialectics." "Graeme Nicholson's new study is marked by its receptiveness to metaphysics in the traditional sense, and contains a critique of the deconstructionist effort to pass beyond metaphysics. It will be of interest to professional philosophers and to theologians, as well as to graduate students and to members of the general public interested in philosophical arguments about the nature of being."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved. (shrink)

The COVID-19 (Coronavirus disease of 2019) pandemic has led to intense conversations about ventilator allocation and reallocation during a crisis standard of care. Multiple voices in the media and multiple state guidelines mention reallocation as a possibility. Drawing upon a range of neuroscientific, phenomenological, ethical, and sociopolitical considerations, the authors argue that taking away someone’s personal ventilator is a direct assault on their bodily and social integrity. They conclude that personal ventilators should not be part of reallocation pools and that (...) triage protocols should be immediately clarified to explicitly state that personal ventilators will be protected in all cases. (shrink)

The programme of work -- Towards a theory of jokes -- The process of joke comprehension -- Text comprehension -- Processing and prediction -- Logic in jokes -- Incongruity and resolution -- Surprise -- The role of language -- Impropriety -- Superiority and aggression -- What's in a joke? -- Applying the framework -- The way forward.

Technology is an increasingly important dimension of social life. This title discusses the impact of technology and science on our lives, exploring how power is demonstrated and reinforced by technological innovation.

Growing-Block theorists hold that past and present things are real, while future things do not yet exist. This generates a puzzle: how can Growing-Block theorists explain the fact that some sentences about the future appear to be true? Briggs and Forbes develop a modal ersatzist framework, on which the concrete actual world is associated with a branching-time structure of ersatz possible worlds. They then show how this branching structure might be used to determine the truth values of future contingents. They (...) point out three different ways of interpreting the logical connectives, which give rise to three different logics of the open future: one supervaluationist, one corresponding to Lukasiewicz's strong Kleene logic, and one intuitionist. (shrink)

The phenomenon of the New Genetics raises complex social problems, particularly those of privacy. This book offers ethical and legal perspectives on the questions of a right to know and not to know genetic information from the standpoint of individuals, their relatives, employers, insurers and the state. Graeme Laurie provides a unique definition of privacy, including a concept of property rights in the person, and argues for stronger legal protection of privacy in the shadow of developments in human genetics. (...) He challenges the role and the limits of established principles in medical law and ethics, including respect for patient autonomy and confidentiality. This book will interest lawyers, philosophers and doctors concerned both with genetic information and issues of privacy; it will also interest genetic counsellors, researchers, and policy makers worldwide for its practical stance on dilemmas in modern genetic medicine. (shrink)

This article enquires into the curriculum advocated in the only ancient Greek treatise concerning education that has survived in its entirety, entitled On the Training of Children. The treatise was highly influential in Europe from the Renaissance to the nineteenth century, and thus exhibits certain assumptions concerning the purpose of curriculum that lie behind the development of western education and may still be influential today. The inquiry is conducted in three stages: the intended recipients of the curriculum are identified; its (...) elements are enumerated and evaluated; and its aims are inferred from the text. I conclude that the curriculum was intended for wealthy, privileged boys, that philosophy (though not independent theorising) was the most valued subject of study and that the aim of the curriculum was to instil in the recipients aristocratic values and modes of behaviour. Finally, some topics are suggested for reflection, in response to these conclusions, upon existing curricula. (shrink)

A number of passages in ancient texts suggest that for much of the archaic and classical periods Eleia was considered a sacred and inviolable land, immune from invasion. While contemporary scholars, referring to the work of Georg Busolt and Eduard Meyer, reject the testimony of Polybios, Strabo, Diodoros and Phlegon in regard to the Eleian asylia, a careful examination of Busolt’S arguments reveals that they are highly speculative. MEYER offers little in addition. Instances of Eleian warfare in the ancient sources, (...) furthermore, are not the conclusive evidence against the asylia that they appear at first glance. (shrink)

This paper examines the legal conception of political parties. It does so by unearthing the history and ontology of the common law relating to political parties in international perspective. The flexibility of the unincorporated association, in which parties are understood through the private law of contract as networks of internal rules or agreements, rather than as legal entities, has proven to be a mask. In the common laws imagination, the ideal party is a ground-up organization animated by its membership. But (...) the law mandates no such thing, and in its statutory and constitutional conception intra-party democracy may be sublimated as parties need be no more than an electoral persona or brand. (shrink)

This article will explore the musicianship of Bishop Charles Henry Davis, osb, coadjutor to Australia's first Catholic Archbishop, John Bede Polding, osb. It will focus on his musical contribution to the early Australian Catholic Church-his ability to improvise, compose, conduct and perform during his short time as bishop at St Mary's, Sydney.

Herbert Marcuse’s One-Dimensional Man is framed as a response to the “end of ideology” thesis of political equilibrium and a criticism of mainstream theoretical construction in advanced industrial countries. Such formulations obscured new forms of self-alienation in totally administered society, and replaced any conceived potential subjectivity with objective laws that govern social relations. One-Dimensional Man is also framed as a response to the “crisis of Marxism” by underscoring the importance of popular ideology in shaping subjective action, which at present, precludes (...) proletarian revolution. (shrink)

The core issue of our target article concerns how relational complexity should be assessed. We propose that assessments must be based on actual cognitive processes used in performing each step of a task. Complexity comparisons are important for the orderly interpretation of research findings. The links between relational complexity theory and several other formulations, as well as its implications for neural functioning, connectionist models, the roles of knowledge, and individual and developmental differences, are considered.

The question of whether a patient has insight is among the first to be considered in psychiatric contexts. There are several competing conceptions of clinical insight, which broadly refers to a patient’s awareness of their mental illness. When a patient is described as lacking insight, there are significant implications for patient care and to what extent the patient is trusted as a knower. Insight is currently viewed as a multidimensional and continuous construct, but competing conceptions of insight still lack consensus (...) on the specifics. Studies also give contradictory evidence regarding the frequency and consequences of poor insight. A number of crucial questions remain unanswered. After outlining some of the key theoretical disagreements about what insight means, I highlight ethical issues that have not received much attention in the literature. Given the conceptual ambiguities and the absence of standardised bedside tools, there are significant ethical concerns about insight assessments. I highlight two main ethical concerns, specifically that these assessments risk: marginalising patients by setting unattainable ideals for self-knowledge and minimising the patient’s own perspective on their mental health. I close with recommendations for documenting and responding to concerns about poor insight, so patients who are vulnerable to losing epistemic trust are better supported in their therapeutic relationships. (shrink)

Robert Veatch’s The Foundations of Justice: Why the Retarded and the Rest of Us Have Claims to Equality delves into deep questions of justice through the case of a child with disabilities. I describe what is basically right about this vision, as well as what is problematic from the standpoint of contemporary disability bioethics. From there, I dive into the notion of vulnerability that is at play in his work. He describes disability as necessarily a condition of weakness, lesser-than existence, (...) and neediness. When disability is viewed in this way as an inherently vulnerable state of being, the essential sociopolitical dimensions of disability receive inadequate attention, which, in turn, makes it impossible to identify injustices correctly. I connect these points to concrete challenges faced by disability communities during the COVID-19 pandemic, which have raised profound questions about the just use of scarce critical care resources. Any case drawn from the pandemic is a very different kind of case than that of the child in Veatch’s book, but a commonality is the question of who should get what limited resources when needs and urgency vary. (shrink)

The right not to know is a contested matter. This can be because the inversion of the normal framing of entitlement to information about one's own health is thought to be illogical and inconsistent with self-authorship and/or because the very idea of claiming a right not to know information is an inappropriate appeal to the discourse of rights that places impossible responsibilities on others. Notwithstanding, there has been a sustained increase in this kind of appeal in recent years fueled in (...) large part by the rise and rise of the importance of personal autonomy in health care ethics, and by domestic and international health law. The right not to know has been acknowledged in at least two important international legal instruments. For example, the UNESCO Universal Declaration on the Human Genome and Human Rights, Article 5c provides: “The right of every individual to decide whether or not to be informed of the results of genetic examination and the resulting consequences should be respected.”. (shrink)