Gene drives are potentially ontologically and morally disruptive technologies. The potential to shape evolutionary processes and to eradicate (e.g. malaria-transmitting or invasive) populations raises ontological questions about evolution, nature, and wilderness. The transformative promises and perils of gene drives also raise pressing ethical and political concerns. The aim of this article is to arrive at a better understanding of the gene drive debate by analysing how ontological and moral assumptions are coproduced in this debate. Combining philosophical analysis with a critical (...) reading of the gene drive literature and an ethnographic study of two leading research groups, the article explores the hypothesis that the development of and debate about gene drives are characterized by a particular intervention-oriented mode of coproduction. Based on the results of this exploration, we highlight the need for a broadening of the perspective on gene drives in which empirical, moral, and ontological concerns are addressed explicitly in their interplay rather than in (disciplinary) isolation from each other. (shrink)

In this article, I address and argue against the tendency to understand the anthropocene as inaugurating the end of nature. I conduct two key moves. First, by way of an engagement with the concept of anthropocene technology I explain how understanding the anthropocene as the end of nature prevents us from recognizing what the anthropocene is all about: interventionism. Secondly, I illustrate how a nondualist understanding of the human-nature relation allows us to recognize interventionism as the hallmark of the anthropocene (...) without falling back into the hierarchical human-nature conceptions that underlie interventionism. A nondualist framework that conserves the human-nature distinction helps us in our ability to relate critically to contemporary science and technology in the anthropocene. I illustrate the conceptual narrative of the article through the specific case of gene drive technology development. (shrink)

In this article, two ways of thinking about the potential disruptiveness of de-extinction and gene drives for conservation are presented. The first way of thinking zooms in on particular technologies and assesses the disruptiveness of their potential implications. This approach is exemplified by a framework proposed by Hopster (2021) that is used to conduct our assessment. The second way of thinking turns the logic of the first around. Here, the question is how gene drives and de-extinction fit into a wider (...) and partly pre-existing context of disruption of human-nature relations. By only zooming in on a particular technology and its potential implications, the context out of which the technology is born is unavoidably disregarded. Gene drives and de-extinction are catalysts of a wider disruption already underway. And it is precisely because this disruption is already underway that the terrain is opened for the development and application of these technologies. In other words, the disruptiveness of these technologies strengthens the disruptiveness that was already underway and vice versa. It is argued that the two ways of thinking about emerging technologies in conservation need to go together, meaning in technology assessment both perspectives need to be included. (shrink)