Tracheostomy with invasive ventilation may be required for the survival of patients at advanced stages of amyotrophic lateral sclerosis. In Japan it has been shown that a proactive approach toward TIV may prolong the survival of ALS patients by over 10 years by preventing the lethal respiratory failure that generally occurs within 3-5 years of the onset of the disease. Measures to prolong life expectancy without foregoing quality of life have produced better results in Japan than in other developed countries. (...) This ‘Japanese bias’ has been attributed to socio-cultural and religious factors as well as to the availability of material resources in Japan. In this article, we use the concepts of onozukara in kadō and amae to illuminate features of patient care that may contribute to this ‘Japanese bias’. (shrink)

Rhodopsins are one of the most studied photoreceptor protein families, and ion‐translocating rhodopsins, both pumps and channels, have recently attracted broad attention because of the development of optogenetics. Recently, a new functional class of ion‐pumping rhodopsins, an outward Na+ pump, was discovered, and following structural and functional studies enable us to compare three functionally different ion‐pumping rhodopsins: outward proton pump, inward Cl− pump, and outward Na+ pump. Here, we review the current knowledge on structure‐function relationships in these three light‐driven pumps, (...) mainly focusing on Na+ pumps. A structural and functional comparison reveals both unique and conserved features of these ion pumps, and enhances our understanding about how the structurally similar microbial rhodopsins acquired such diverse functions. We also discuss some unresolved questions and future perspectives in research of ion‐pumping rhodopsins, including optogenetics application and engineering of novel rhodopsins. (shrink)

Rauszer and Sabalski proved in [2] that distributivity with respect to infi- nite joins and meets is a sucient and necessary condition making the RasiowaSikorski Lemma valid in distributive lattices. The main part of their proof is a direct construction of a required filter under distributivity. In this note we show that a generalization of the result can be obtained from the Rasiowa-Sikorski Lemma for Boolean algebras by using Gornemann’s result in [1] instead of a direct con- ¨ struction. Suppose (...) A is a distributive lattice and Q; R 2 A f;g. We call A complete if 8M 2 Q9 M 2 A and 8N 2 R9 F N 2 A. M 2 Q is -dis if 9 M 2 A and 8a 2 A a t M = m2M. N 2 R is F -dis if 9 F N 2 A and 8a 2 A a u F N = F n2N. is called distributive if every M 2 Q is -dis and every N 2 R is F -dis. Suppose A is complete and C; D A. By rC we mean the filter in A generated by C, in particular, let r; = ; = ;. is called complete if and , where 8M 2 Q 9m 2 MrC \ D[fmg = ;) 8N 2 R 9n 2 NrC[fng \ D = ;). (shrink)

This paper investigates the semantics of measure phrases in Japanese. Based on new data, we argue that the interpretation of measure phrases in Japanese is sensitive to scale structure such that (i) measure phrases are introduced by a degree morpheme that selects only for gradable predicates whose scale contains a minimal element (i.e., a lower closed scale) and (ii) violations to this restriction are repaired via coercion, which forces a comparative interpretation with a contextually determined standard and hence a minimal (...) element. We compare the Japanese facts to data in other languages and argue that the requirement of having a minimal element is not specific to Japanese, but universal. We show that languages may vary in how they deal with potential violations of this universal constraint, including coercion of a contextually recoverable derived minimal element (Japanese), ungrammaticality (e.g., Spanish, Korean, Russian), and a hybrid system of ungrammaticality for some adjectives and allowed constraint violation for others (e.g., English, German, Italian). (shrink)

In political philosophy, reflective equilibrium is a standard method used to systematically reconcile intuitive judgments with theoretical principles. In this paper, we propose that survey experiments and a model selection method—i.e., the Akaike Information Criterion (AIC)-based model selection method—can be viewed together as a methodological means of satisfying the epistemic desiderata implicit in reflective equilibrium. To show this, we conduct a survey experiment on two theories of distributive justice, prioritarianism and sufficientarianism. Our experimental test case and AIC-based model selection method (...) demonstrate that the refined sufficientarian principle, a widely accepted principle of distributive justice, is no more plausible than the prioritarian principle. This tells us that some changes of certain intuitions revolving around sufficientarianism should be examined (separately) based on the findings of the survey experiment and AIC model selection. This shows the potential of our approach—both practically and methodologically—as a novel way of applying reflective equilibrium in political philosophy. (shrink)

サイエンス・ウォーズそのものを扱った長編論文。サイエンス・ウォーズという現象が起きた理由を理論的に跡づけるために、その学問的背景に関する分析の試み。そして、ケーススタディという構成。.

This book, written by one of the leading Japanese scholars in the philosophy of agricultural science, examines the relationship between human life, the natural environment, and agriculture.

The social and cultural causes behind the widespread use and acceptance of robots in Japan are not yet completely understood. This study compares humans and robots in images gathered through Google searches in Japanese and in English. Numerous pictures obtained by the search in Japanese were found to have a human and a robot looking together at something else (“third item”), whereas many of the images acquired by search in English show a human and a robot facing each other. This (...) is similar to the composition of mother and child in paintings: in _ukiyo-e_ that was painted mainly in the Edo period of Japan, the mother and child are often depicted together viewing something other than themselves, whereas this is not the case in Western paintings of mother and child. It has also been pointed out that, in modern Western paintings, the world inside the picture is separated from the outside world, forming an independent microcosmos, whereas the inside and outside are continuous in Japanese paintings. These may indicate that, in Japanese society, robots are to a certain extent regarded as fellow human beings who can share the third item. In Western society, on the other hand, no code is embedded that can fix robots’ superiority or inferiority to humans, which would easily trigger an antagonistic view toward artificial intelligence (AI)/robots as threatening entities, as shown in most of Western literature and movies. We suggest that such cultural characteristics of Japanese society can contribute to enhance coexistence with AI/robots. (shrink)

Originally published as 「明治の哲学界：有機体の哲学とその系譜」in 井上克人編『豊饒なる明治』, Kansai Daigaku Shuppannbu, 2012, 3–22. Translated by Morisato Takeshi. German Idealism was introduced to Japanese intellectuals in the middle of Meiji era and was mainly received from a mystical or religious perspective, as we see in Inoue Tetsujirō’s “harmonious existence,” Inoue Enryō’s “unity of mind and body,” and Kiyozawa Manshi’s “existentialism.” Since these theories envisioned true reality as a unified and living whole, I group them under the label “philosophy of organism” and from (...) there argue that their conviction that “all is truth and truth is all” was shaped in large part by the Awakening of Faith in the Mahayana. The understanding of Buddhist concepts by Meiji philosophers was philosophical in its content, and those who devoted themselves to the study of Western philosophy were encouraged to describe Eastern thought in Western philosophical terms. As a result, the philosophical world of the Meiji era developed an original standpoint that unified Eastern and Western perspectives by means of a logic of “phenomena-in-reality.”. (shrink)

法は危機をこえてどう変容するのか!法的議論の分裂、立憲主義の錯綜、正統性のゆらぎ―法が危機にあるいま、従来の支配的見解を根本的に問い、オルタナティヴ理論を提示する。.

巧緻を極めた完全犯罪の罠ともいうべき言葉の繭を破り「神」と「死」の謎に迫る、躍動感溢れる究極の探究報告。「いま」生きているこの現場の徹底究明。.

Ce texte propose un essai d’interprétation des contes de Kenji Miyazawa à la lumière de la théorie de l’imagination matérielle de Gaston Bachelard. Il s’agit d’une mise à l’épreuve de ce cadre conceptuel dans un contexte culturel totalement différent. Ces contes de fées japonais sont relus en fonction de leurs évocations des quatre éléments d’Empédocle. Ces quatre éléments révèlent une source d’inspiration inconsciente des expressions et des intrigues de cet auteur japonais. Dans son cas, je montrerai que la terre est (...) l’élément dominant. (shrink)

The Japanese comparative adverb motto has two different uses. In the degree use, motto compares two individuals and denotes that there is a large gap between the target and a given standard with a norm-related presupposition. On the other hand, in the so-called ‘negative use’ it conveys the speaker’s attitude toward the utterance situation. I argue that similarly to the degree motto, the negative motto is a comparative morpheme, but unlike the degree motto it compares a current situation and an (...) expected situation at the level of conventional implicature /expressive. I argue that the speaker’s negative evaluation of the utterance situation in question comes from the large gap between the expected degree and the current degree. The theoretical implications of this paper are that there is a natural extension from semantic comparison to expressive comparison and that there is a type in natural language that can be called an ‘indirect expressive’, as opposed to ‘direct expressives’ like bastard and man. (shrink)

This study investigates interpretations of the Japanese initial mora-based minimizer “X.Y...”-_no_ “X”-_no ji-mo_ ‘lit. even the letter “X” of “X.Y...”.’ Although initial mora-based minimizers have a literal interpretation of _ji_ ‘letter’, they have a non-literal interpretation as well. The non-literal interpretation has several distinctive features that are not present in ordinary minimizers. First, it is highly productive in that various expressions can appear in the form “X.Y...”-_no_ “X”-_no ji_. Second, non-literal minimizers typically co-occur with predicates that relate to knowledge, information, (...) concepts, thought, and habituality, as seen in the corpus data (Balanced Corpus of Contemporary Written Japanese [BCCWJ]). I argue that in the non-literal use, X refers to the minimum on the scale of the main predicate concerning “X.Y...”. I suggest that the non-literal use was developed as a result of the conventionalization of the pragmatic inference derived from the literal reading, and that the co-occurrence with predicates related to knowledge, information, knowledge, concepts, thought, or habituality is due to the interpretation of “X.Y...”, which were originally interpreted as letters as an abstract concept. The theoretical implication of this study is that, in addition to a non-compositional (lexically specified) minimizer whose scale is lexically fixed (e.g., _give a damn_, _lift a finger_), there also exists a compositional (lexically unspecified) minimizer in natural language, whose scale is specified via the predicate with which the minimizer co-occurs. The last section of this paper briefly discusses similar/related phenomena in Bosnian/Croatian/Serbian, Korean, and English from a cross-linguistic perspective. (shrink)

BackgroundThis essay provides an ethical and conceptual argument for the use of informed consent prior to the diagnosis of brain death. It is meant to enable the family to make critical end-of-life decisions, particularly withdrawal of life support system and organ donation, before brain death is diagnosed, as opposed to the current practice of making such decisions after the diagnosis of death. The recent tragic case of a 13-year-old brain-dead patient in California who was maintained on a ventilator for over (...) 2 years illustrates how such a consent would have made a crucial difference.MethodsConceptual, philosophical, and ethical analysis.ResultsI first consider a conceptual justification for the use of consent for certain non-beneficial and unwanted medical diagnoses. I suggest that the diagnosis of brain death falls into this category for some patients. Because the diagnostic process of brain death lacks the transparency of traditional death determination, has a unique epistemic structure and a complex risk-benefit profile which differs markedly from case to case, and presents conflicts of interest for physicians and society, I argue that pre-diagnostic counseling and informed consent should be part of the diagnostic process. This approach can be termed as “allow cardiac death”, whose parallel logic with “allow natural death” is discussed. I also discuss potential negative impacts on organ donation and health care cost from this proposal and offer possible mitigation. I show that the pre-diagnostic counseling can improve the possibility for well-thought-out decisions regarding organ donation and terminating life-support system in cases of hopeless prognosis. This approach differs conceptually from the pluralism of the definition of death, such as those in New Jersey and Japan, and it upholds the Uniform Determination of Death Act.ConclusionsMy intention is not to provide an instant panacea for the ongoing impasse of the brain death debate, but to point to a novel conceptual ground for a more pragmatic, and more patient- and family-centered approach. By enabling the family to consent to or decline the diagnostic process of brain death, but not to choose the definition of death, it upholds the current legal definition of death. (shrink)

Naturalistic teleological accounts of mental content rely on an etiological theory of function. Nanay has raised a new objection to an etiological theory, and proposed an alternative theory of function that attributes modal force to claims about function. The aim of this paper is both to defend and to cast a new light on an etiological theory of function. I argue against Nanay’s “trait type individuation objection,” suggesting that an etiological theory also attributes modal force to claims about function. An (...) etiological theory of function can be thought to analyze claims about function with modal force, not relying on any theory of counterfactuals. (shrink)

A dialectical contradiction can be appropriately described within the framework of classical formal logic. It is in harmony with the law of noncontradiction. According to our definition, two theories make up a dialectical contradiction if each of them is consistent and their union is inconsistent. It can happen that each of these two theories has an intended model. Plenty of examples are to be found in the history of science.

This chapter reviews fundamental ethical controversy surrounding the ongoing effort to revise the Uniform Determination of Death Act in the United States. Instead of focusing on the process of the revision itself, the chapter explores the underlying ethical debate over brain death that has been ongoing for many decades and finally culminated in this revision. Three issues are focused: the requirement for consent and personal exemptions before applying brain death for the diagnosis of death; redefining the areas of the brain (...) that have ceased to function in the definition of brain death; and codifying the American Academy of Neurology as the authority to issue the standards of the diagnosis of brain death. The chapter concludes that allowing the personal choice of death determination gives a pragmatic compromise to the disputed definition and practice of diagnosing brain death. So long as all risks and imperfections of the diagnosis are accepted through the consenting process, there is nothing ethically objectionable to continuing the current practice of diagnosing brain death as a successful tool to facilitate heart-beating organ donation without violating the dead-donor rule. By contrast, precluding personal choice and imposing legal restrictions to consent and exemptions would further erode public trust. (shrink)

The aim of this essay is to elaborate philosophical and ethical underpinnings of posthumous diagnosis of famous historical figures based on literary and artistic products, or commonly called retrospective diagnosis. It discusses ontological and epistemic challenges raised in the humanities and social sciences, and attempts to systematically reply to their criticisms from the viewpoint of clinical medicine, philosophy of medicine, particularly the ontology of disease and the epistemology of diagnosis, and medical ethics. The ontological challenge focuses on the doubt about (...) the persistence of a disease over historical time, whereas the epistemic challenge disputes the inaccessibility of scientific verification of a diagnosis in the past. I argue that the critics are in error in conflating the taxonomy of disease and the act of diagnosing a patient. Medical diagnosis is fundamentally a hypothesis-construction and an explanatory device that can be generated under various degrees of uncertainty and limited amount of information. It is not an apodictic judgment as the critics presuppose, but a probabilistic judgment with varying degrees of plausibility under uncertainty. In order to avoid this confusion, I propose that retrospective diagnosis of a historical figure be syndromic without identifying underlying disease, unless there is justifiable reason for such specification. Moreover it should be evaluated not only from the viewpoint of medical science but also in a larger context of the scholarship of the humanities and social sciences by its overall plausibility and consistency. On the other hand, I will endorse their concerns regarding the ethics and professionalism of retrospective diagnosis, and call for the need for situating such a diagnosis in an interdisciplinary scope and the context of the scholarship of the historical figure. I will then enumerate several important caveats for interdisciplinary retrospective diagnosis using an example of the retrospective diagnosis of Socrates for his life-long intermittent neurologic symptoms. Finally, I will situate the present argument in a larger context of the major debate among the historians of medicine and paleopathologists, and discuss the similarities and differences. (shrink)

We prove the strong normalization theorem for the natural deduction system for the constructive arithmetic TRDB (the system with Definition by Transfinite Recursion and Bar induction), which was introduced by Yasugi and Hayashi. We also establish the consistency of this system, applying the strong normalization theorem.

This paper replies to Nanay’s response to my recent paper. My suggestions are the following. First, “should” or “ought” does not need to be deontic. Second, etiological theories of function, like provability logic, do not need to attribute modal force to their explanans. Third, the explanans of the homological account of trait type individuation does not appeal to a trait’s etiological function, that is, what a trait should or ought to do. Finally, my reference to Cummins’s notion of function was (...) intended to note that the homological account is permitted to use this non-etiological notion of function. (shrink)

Nakamura proposed two three-valued temporal logics. We present two extended Gentzen-type formulations of these logics. Then we prove the soundness as well as the completeness theorem.

There are two contrasting views on the decision-making for life-sustaining treatment in advanced stages of dementia when the patient is deemed incompetent. One is to respect the patient's precedent autonomy by adhering to advance directives or using the substituted judgement standard. The other is to use the best-interests standard, particularly if the current judgement on what is best for the incapacitated patient contradicts the instructions from the patient's precedent autonomy. In this paper, I argue that the protracted clinical course of (...) dementia over many years requires the extended perspective of a progressive decision-making process—extended in both social space and time. The ongoing debate between these two competing views has missed this perspective by focussing on an exclusive disjunction between the competent former self and the incompetent current self. Drawing on theories of situated cognition in cognitive science, I will show that the cognition of a demented patient can be viewed as extended and embodied by her supportive social environment. As the disease progresses, the content of the mind of a demented person becomes partially constituted by such external resources along with her diminishing intrinsic mind. With this understanding, medical decision-making for a demented patient can be construed as a temporally and socially extended practice. A collective decision-making body consisting of the patient, her family and surrogates, and the clinician, should make progressive decisions as a whole over years of the disease course. Finally, I will provide a practical example of how this proposal can be applied in clinical practice. (shrink)

This chapter traces the evolution of Japan's systems of household and land registration from c.1600 to the period of early Meiji reforms in the 1870s and 1880s, with due attention to the distinction between a system designed by the state and local forms of registration practice. In the section on the pre-Meiji period, one such local practice of having people ‘disowned’ and its consequence — registerlessness — is examined. The section on the Meiji reforms and the section that follows turn (...) to the issue of continuity and discontinuity, and the question of whether any progress was made by those reforms. In order to illustrate the actual changes that took place at the local level, the chapter begins with an eighteenth-century story about a peasant woman and ends with a case of a family dispute that another village woman brought before the court some 120 years later. (shrink)

This essay provides a medical theory that could clarify enigmas surrounding the historical Socrates. It offers textual evidence that Socrates had temporal lobe epilepsy and that its two types of seizure manifested as recurrent voices and peculiar behaviour, both of which were notorious hallmarks of Socrates. Common and immediate criticisms against the methodology of retrospective diagnosis are addressed first. Next, the diagnostic reasoning is presented in detail. The possibility of temporal lobe personality in Socrates is also considered. The important implication (...) of this theory is that one of the charges against Socrates, introducing new divinities, was a now well-known neurologic symptom. (shrink)