The unificationist theory of causal explanation offers a theory of causation and explanation with no causal primitives. Kitcher proposed that it offered an account of explanatory asymmetry, but his proposal has been criticized for being too dependent on contingent facts and surreptitiously supposing causal realism. In addition, critics have argued that unificationism cannot account for asymmetry in a world with symmetric laws of physics and is lead to accept backwards explanation in certain epistemic situations. Unificationism has been defended from some (...) of these objections. We critique those defenses, rejecting some and developing others, as well as adding new ones. In doing so, we argue that objectors are wrong to treat explanatory asymmetry as an a priori matter and that unificationism is appropriately sensitive to the right sort of empirical facts. (shrink)

Embryos, cells, genes, and organisms : reflections on the history of evolutionary developmental biology / Manfred D. Laubichler and Jane Maienschein The organismic systems approach : streamlining the naturalistic agenda / Werner Callebaut, Gerd B. Müller, and Stuart A. Newman Complex traits : genetics, development, and evolution / H. Frederik Nijhout Functional and developmental constraints on life-cycle evolution : an attempt on the architecture of constraints / Gerhard Schlosser Legacies of adaptive development / Roger Sansom Evo-devo meets the (...) mind : toward a developmental evolutionary psychology / Paul E. Griffiths Reproducing entrenchments to scaffold culture : the central role of development in cultural evolution / William C. Wimsatt and James R. Griesemer. (shrink)

This contribution to the adaptationism debate elaborates the nature of constraints and their importance in evolutionary explanation and argues that the adaptationism debate should be limited to the issue of how to privilege causes in evolutionary explanation. I argue that adaptationist explanations are deeply conceptually dependent on developmental constraints, and explanations that appeal to constraints are dependant on the results of natural selection. I suggest these explanations should be integrated into the framework of historical causal explanation. Each strategy explicitly appeals (...) to some aspect of the evolutionary process, while implicitly appealing to others. Thus, adaptationists and anti-adaptationists can offer complementary causal explanations of the same explanandum. This eliminates much of the adaptationism debate and explains why its adversaries regularly agree with each other more than they would like. The adaptationism issue that remains is a species of the general issue of how to privilege causes in explanation. I show how a proposed solution to this general problem might be brought to bear on evolutionary explanations, and investigate some difficulties that might arise due to the nature of the evolutionary process. (shrink)

One current version of the internalism/externalism debate in evolutionary theory focuses on the relative importance of developmental constraints in evolutionary explanation. The received view of developmental constraints sees them as an internalist concept that tend to be shared across related species as opposed to selective pressures that are not. Thus, to the extent that constraints can explain anything, they can better explain similarity across species, while natural selection is better able to explain their differences. I challenge both of these aspects (...) of the received view and propose a hierarchical view of constraints. (shrink)

I show that gene regulation networks are qualitatively consistent and therefore sufficiently similar to linearly seperable connectionist networks to warrant that the connectionist framework be applied to gene regulation. On this view, natural selection designs gene regulation networks to overcome the difficulty of development. I offer some general lessons about their evolvability that can be learned by examining the generic features of connectionist networks.

Understanding the operation and evolution of gene regulation networks is critical to understanding ontogeny and evolution. According to Stuart Kauffman's view, (1) each cell type cycles through its own repeated pattern of gene expression, (2) the order of ontogeny is dependent on these cycles being short, and (3) evolution is possible because these cycles mutate gradually. This view of gene regulation reflects Kauffman's view that ontogeny is fundamentally the process of cells repeating cycles of activity. I criticize Kauffman's view of (...) gene regulation networks and offer the connectionist theory of gene regulation as an alternative. On this view, the generic order of gene regulation mechanisms is due to the qualitatively consistent way that one gene product influences the expression of another. This allows networks to be stable and evolve to regulate accurately, allowing cells to react appropriately to their microenvironments, due to design by natural selection. 1. Introduction2. Kauffman's Model of Gene Regulation3. Explaining the Order of Kauffman's K = 2 Networks4. The Importance and Relevance of Kauffman's Explanations of the Order of Gene Regulation5. Additional Orderly Facts of Transcription6. The Order of Network Accuracy7. The Accuracy of Connectionist Networks8. The Evolvability of Gene Regulation Networks9. Laws of Structure. (shrink)

Empirical advances in biology led to the popularity of a view known as gene selectionism, most recently championed by Richard Dawkins' "The Selfish Gene" . On this view, natural selection "looked through" the organism right to the genome; evolution was a change in the genomes of a species over time and the process of development is rendered epiphenominal to that process. Recently, support for gene selectionism has waned in favor of a pluralistic view. On this view, natural selection operates at (...) many different levels, including: genes, traits of organisms, organisms, groups, species and clades. Because the process of development occurs at many of these levels, a complete understanding of evolution will include an understanding of the developmental process. This dissertation is a contribution to the integration of evolution and development that has become known as the developmental synthesis. ;I argue that the adaptationism debate has raged for so long because it is based on an incoherent picture of the world, according to which, some traits are due to natural selection and others are due to constraints. In fact, all traits are due to both natural selection and constraints. Whether we explain a trait in terms of natural selection or constraints is a matter of pragmatics. Evolutionary explanations are causal explanations and different types of evolutionary explanations appeal to different aspects of the evolutionary process. ;I also offer two general theories on how natural selection can design organisms capable of complex development. The first focuses on the nature of gene control networks. I argue that they are connectionist networks designed by natural selection to overcome the difficulty of development. The second focuses on the evolvability of ontogeny. I argue that ontogeny can be designed by natural selection for increased evolvability, primarily through designed functional modularity. (shrink)

James Shapiro’s view of evolution is inspired by looking at the molecular mechanisms of mutation. Finding these systems to be intelligent and the mutations non-gradual, Shapiro concludes that neither the role of DNA in development, nor and the role of natural selection in evolution are what we thought them to be. The cases discussed are interesting and may require some modification of theory in biology, but this reviewer finds many of Shapiro’s conclusions unwarranted.

Roger Sansom and Robert N. Brandon (eds.): Integrating Evolution and Development: From Theory to Practice Content Type Journal Article Pages 81-86 DOI 10.1007/s10441-010-9121-x Authors Thomas A. C. Reydon, Institute of Philosophy & Center for Philosophy and Ethics of Science (ZEWW), Leibniz Universität Hannover, Im Moore 21, 30167 Hannover, Germany Journal Acta Biotheoretica Online ISSN 1572-8358 Print ISSN 0001-5342 Journal Volume Volume 59 Journal Issue Volume 59, Number 1.

This volume provides a philosophical introduction to and analysis of the study of metaphor. By proceeding from the concrete analysis of complex metaphors, White is able to identify a range of features which are incompatible with standard accounts of the way words function in metaphor.

This book introduces student to the three major figures of modern philosophy known as the rationalists. It is not for complete beginners, but it is an accessible account of their thought. By concerning itself with metaphysics, and in particular substance, the book relates an important historical debate largely neglected by the contemporary debates in the once again popular area of traditional metaphysics. in philosophy. (Do Not USE).

Berkeley's idealism started a revolution in philosophy. As one of the great empiricist thinkers he not only influenced British philosophers from Hume to Russell and the logical positivists in the twentieth century, he also set the scene for the continental idealism of Hegel and even the philosophy of Marx. -/- There has never been such a radical critique of common sense and perception as that given in Berkeley's Principles of Human Knowledge (1710). His views were met with disfavour, and his (...) response to his critics was the Three Dialogues between Hylas and Philonous. -/- This edition of Berkeley's two key works has an introduction which examines and in part defends his arguments for idealism, as well as offering a detailed analytical contents list, extensive philosophical notes and an index. (shrink)

Introduction: Conversion and the practice of transformation -- The philosophical structure of Jonathan Edwards's religious affections -- Habit, habit change, and conversion in C.S. Peirce -- Reconstructing faith : religious overcoming in Dewey's pragmatism -- Transforming obligation in William James -- Dwelling in absence: the reflective origin of conversion -- Creative transformation : the work of conversion -- The evasion of conversion in recent American philosophy.

Introduction -- The mathematical roots of the concept of analogy -- Aristotle : the uses of analogy -- Aristotle : analogy and language -- Thomas Aquinas -- Immanuel Kant -- Karl Barth -- Final reflections.

Synaesthesia is considered a rare perceptual capacity, and one that is not capable of cultivation. However, meditators report the experience quite commonly, and in questionnaire surveys, respondents claimed to experience synaesthesia in 35% of meditation retreatants, in 63% of a group of regular meditators, and in 86% of advanced teachers. These rates were significantly higher than in nonmeditator controls, and displayed significant correlations with measures of amount of meditation experience. A review of ancient texts found reports suggestive of synaesthesia in (...) advanced meditators from India and China. These findings suggest that synaesthesia may be cultivated by meditation, and that laboratory studies of meditators could be rewarding. (shrink)

This paper argues for two theses: that degrees of belief are context sensitive; that outright belief is belief to degree 1. The latter thesis is rejected quickly in most discussions of the relationship between credence and belief, but the former thesis undermines the usual reasons for doing so. Furthermore, identifying belief with credence 1 allows nice solutions to a number of problems for the most widely-held view of the relationship between credence and belief, the threshold view. I provide a sketch (...) of a formal framework on which both theses are true. This is a modified Bayesian framework; I argue that despite making credences context-sensitive, the framework lets Bayesians hold on to their signature explanatory successes. The sort of context-sensitivity claimed for credences here mirrors the sort of context-sensitivity I have elsewhere claimed for outright belief: one's credences depend, in part, on the space of alternative possibilities one takes seriously in a context. (shrink)

This is a three-part exchange on the relationship between belief and credence. It begins with an opening essay by Roger Clarke that argues for the claim that the notion of credence generalizes the notion of belief. Julia Staffel argues in her reply that we need to distinguish between mental states and models representing them, and that this helps us explain what it could mean that belief is a special case of credence. Roger Clarke's final essay reflects on the (...) compatibility of the previously discussed views with dualist and monist interpretations of our mental states and our ways of modeling them. (shrink)

Can we justify our most basic beliefs about morality, religion and the nature of the world? Can there be a rational and objective way of choosing between alternative societies, modes of life or world-views? Dr Trigg shows how philosophical analysis is relevant to these questions and criticizes the tendency to emphasize notions of commitment and convention at the expense of truth and reason. He draws parallels between issues that are often too isolated from each other and identifies a cluster of (...) related ideas, all of which stress the notion of self-contained conceptual systems that define their own standards of rationality. First published in 1973, this book will interest professional philosophers as a vigorous and distinctive exposition of several fundamental philosophical problems and more especially it can be used as an introduction for students to a wide range of philosophical problems. (shrink)

Journal of Philosophy of Education, Volume 56, Issue 2, Page 342-355, April 2022.

Leslie Graves, Barbara Horan and Alex Rosenberg (1999) have argued that the process of evolution is really deterministic, so we should be instrumentalists about our probabilistic evolutionary theory. I criticize the consistency of their view. I argue that because they are realists towards multiple theories (quantum mechanics and macrophysics) their arguments against realism for another scientific theory fail. The main point of this paper is critical, but in order to set up this criticism I explore the ramifications of realism for (...) multiple theories. Finally, I offer a brief metaphysical justification for realism about multiple theories. This view justifies realism for evolutionary theory, which has been defended by Robert Brandon and Scott Carson (1996). (shrink)

Art works provide a unique and influential way to teach human virtues because they can place individuals (or particular artistic expressions) within the ambiguities, complexities, and forces of the human experience. I use four art works to teach about the virtue of kindness: Giotto di Bondonie's Scene 2: St. Francis Giving His Mantle to a Poor Man; Bishop Charles Francois in Victor Hugo's Les Misérables; Adam in William Shakespeare's As You Like It; and Sonya in Fyodor Dostoevsky's Crime and Punishment. (...) In these four examples, we see necessary characteristics of being a kind person: supererogatory behavior, altruistic behavior, a display of the way the world ought to be, and the presence of a kind soul. (shrink)

This paper defends moral testimony pessimism, the view that there is something morally or epistemically regrettable about relying on the moral testimony of others, against several arguments in Lillehammer. One central such argument is that reliance on testimony is inconsistent with the exercise of true practical wisdom. Lillehammer doubts whether such reliance is always objectionable, but it is important to note that moral testimony pessimism is best understood as a view about the pro tanto, rather than the overall, badness of (...) relying on testimony. One must also be clear about what counts as genuine moral testimony: there will be morally charged occasions when a virtuous person will properly rely on the views of others. It can also plausibly be argued that relying on moral testimony may constitute a lack of full autonomy. After discussing some remaining issues concerning the definition of moral testimony, a possible analogy between lying and relying on testimony, and the implications of untrustworthiness for the truth of moral testimony pessimism, the paper ends with a return to the case against relying on moral testimony, grounded on a conception of the role of knowledge and understanding in virtue. (shrink)

Explaining the behaviour of ecosystems is one of the key challenges for the biological sciences. Since 2000, new-mechanicism has been the main model to account for the nature of scientific explanation in biology. The universality of the new-mechanist view in biology has been however put into question due to the existence of explanations that account for some biological phenomena in terms of their mathematical properties (mathematical explanations). Supporters of mathematical explanation have argued that the explanation of the behaviour of ecosystems (...) is usually provided in terms of their mathematical properties, and not in mechanistic terms. They have intensively studied the explanation of the properties of ecosystems that behave following the rules of a non-random network. However, no attention has been devoted to the study of the nature of the explanation in those that form a random network. In this paper, we cover that gap by analysing the explanation of the stability behaviour of the microbiome recently elaborated by Coyte and colleagues, to determine whether it fits with the model of explanation suggested by the new-mechanist or by the defenders of mathematical explanation. Our analysis of this case study supports three theses: (1) that the explanation is not given solely in terms of mechanisms, as the new-mechanists understand the concept; (2) that the mathematical properties that describe the system play an essential explanatory role, but they do not exhaust the explanation; (3) that a non-previously identified appeal to the type of interactions that the entities in the network can exhibit, as well as their abundance, is also necessary for Coyte and colleagues’ account to be fully explanatory. From the combination of these three theses we argue for the necessity of an integrative pluralist view of the nature of behaviour explanation when this is given by appealing to the existence of a random network. (shrink)

Perspectives on Quine, now available in paperback, is a collection of twenty-one new essays dealing with the thought of America's most distinguished living philosopher, Willard Van Orman Quine. After the editors' brief introduction to Quine's thought, the volume opens with an important new essay by Quine entitled Three Indeterminacies. The essays that follow, written by leading philosophers, are rich with insights into a wide variety of Quine's concerns ranging from logic and set theory to natural language, truth, evidence, natural kinds, (...) naturalized epistemology, and much more. Each essay concludes with a summary and response from Quine himself. (shrink)

: Tolstoy critiques the assumption one can live a meaningful life merely by following social conventions. Though they may give a semblance of control, they do not prepare one to face mortality. Compassion for others enables one to transmute a preoccupation with filling one's preferences and desires to an appreciation of others and one's individuality. In telling of Ivan's death, Tolstoy shows the ineffectiveness of the practice of medicine and marriage when they are treated only as conventions.