The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

Moral distress has been characterised as one of the main ethical problems affecting nurses in all health systems, and has been depicted as a threat to nurses’ integrity and to the quality of patient care. In recent years, several studies tried to investigate moral distress, its causes and consequences for health professionals, clients and organisations. However, such studies are considered controversial and vulnerable, mainly because they lack a solid philosophical and empirical basis. The present article aimed at elaborating a theoretical (...) model for moral distress, considering the process of moral deliberation, spaces of power and resistance and patient advocacy, and sought to carry out a reflection that culminated with the creation of a broader concept of moral distress. (shrink)

I review and challenge the views on simplicity and its role in linguistics put forward by Ludlow. In particular, I criticize the claim that simplicity—in the sense pertinent to science—is nothing more than ease of use or “user-friendliness”, motivated by economy of labor. I argue that Ludlow’s discussion fails to do justice to the diversity of factors that are relevant to simplicity considerations. This, in turn, leads to the neglect of crucial cases in which the rationale for simplification is unmistakably (...) epistemic, as well as instances where simplicity is part of the content of substantive, empirical hypotheses. I illustrate these points with examples from the history of generative linguistics, such as: the shaping influence exerted by simplicity, via its involvement in the notion of “linguistically significant generalization”, its methodological and substantive contribution to the goal of explanatory adequacy, and its central role in the Minimalist Program’s search “beyond explanatory adequacy”. (shrink)

This article deals with the cognitive relationship between a speaker and her internal grammar. In particular, it takes issue with the view that such a relationship is one of belief or knowledge (I call this view the ‘Propositional Attitude View’, or PAV). I first argue that PAV entails that all ordinary speakers (tacitly) possess technical concepts belonging to syntactic theory, and second, that most ordinary speakers do not in fact possess such concepts. Thus, it is concluded that speakers do not (...) literally ‘know’ or ‘believe’ much of the contents of their grammars, and moreover, that these contents can only be attributed at a subpersonal level. (shrink)

The aim of this paper is to provide an approach to the etho-aesthetic dimension in Marcuse’s thought. The approach in this paper is built upon the following thesis: the etho-aesthetic dimension consists of the transformation of subjectivity based on artistic sensitivity and critical rationality from which social relations opposed to an advanced industrial society and its one-dimensional man are reconstructed materially and intellectually. The conclusion is the following: a Marcusian critical theory, inherited from Marx and Schiller, would be one capable (...) of analyzing the potential qualitative changes of the subjects and social institutions to generate a higher level of rational development, equitable in the distribution of resources and in the generation of greater spaces of freedom. Its basis would be an etho-aesthetic attitude that does not take pleasure in squandering, but in the reflective experience of the sensible. (shrink)

In this paper I defend the “Standard View” of the semantics of ‘I’—according to which ‘I’ is a pure, automatic indexical—from a challenge posed by “deferred reference” cases, in which occurrences of ‘I’ are (allegedly) not speaker-referential, and thus non-automatic. In reply, I offer an alternative account of the cases in question, which I call the “Description Analysis” (DA). According to DA, seemingly deferred-referential occurrences of the first person pronoun are interpreted as constituents of a definite description, whose operator scopes (...) over an open sentence Rxy—where R is a contextually selected relation ranging over pairs of people and objects. The role of intentions is thus limited to the determination of R, which is posterior to the fixation of the reference of ‘I’. In support of the DA I present evidence that, in the cases in question, the (Determiner) phrase containing ‘I’ behaves in relevant ways like a description. I show that the DA can account for the problematic examples, while preserving the simplicity of the standard semantics of ‘I’. Finally, I examine a rival account of the data, offered by Nunberg (Linguist Philos 16:1–43, 1993), and argue for the superiority of the DA. (shrink)

O presente artigo tem por objetivo destacar a importância da felicidade dentro do sistema moral kantiano, mesmo que ela esteja baseada nos sentimentos de prazer e desprazer, ou seja, proveniente da ordem empírica. Para isso, faz-se necessário diferenciar deveres diretos de deveres indiretos, ou seja, os primeiros como deveres perfeitos que são obrigatórios e necessários, e os últimos como imperfeitos, que dizem respeito simplesmente àquilo que é bom que se faça, por isso são altamente recomendáveis. Os deveres indiretos ou imperfeitos, (...) que nada mais são do que deveres de virtude, somente tendem a acrescentar à qualificação moral. O dever indireto de promover a felicidade coloca-se, na filosofia prática de Kant, como um meio para a moralidade, visto que a falta de felicidade pode apresentar-se como um obstáculo à prática moral e não o contrário. (shrink)

Según la Propositional Attitude View (PAV), un hablante es competente en su idioma en virtud de poseer actitudes proposicionales cuyo contenido es su gramática interna. En este artículo desarrollo una objeción a PAV, llamada �el reto de la integración�, originalmente propuesto por Stich (1978) y Evans (1981), y que está constituido por dos premisas: (1) las actitudes proposicionales se caracterizan por su integración inferencial, y (2) los estados que contienen información gramatical no están inferencialmente integrados. En este artículo considero y (...) rechazo las respuestas a este argumento formuladas por Dwyer y Pietroski (1996), Higginbotham (1987) y Knowles (2000). (shrink)

As tentativas de invasões germânicas iniciadas no século II a.C. culminaram com a tomada de Roma em 476. Os novos chefes adotaram o latim como língua oficial, e grande parte dos textos latino-germânicos foi reunida e publicada por G.H.Pertz (MGH).

Ethical issues flow from and are embedded in contexts of practice. Contexts of practice refer to the diverse social settings where interventions occur. Primary prevention activities require new professional roles in these diverse social settings. These new roles engage the professional in new activities, which in mm allow new ethical issues to arise. This article takes an ecological perspective on ethical issues arising from the enactment of new preventive roles intended to affect groups or communities. Within this perspective, the concepts (...) of context and culture take on special conceptual significance. Four ecological assumptions about preventive interventions intended to affect groups or communities are offered as a means of framing ethical issues in such interventions. Finally, several approaches to developing ecological knowledge about the contexts of practice are presented as ways of furthering our ability to conceptualize and cope with ethical issues in preventive interventions intended to affect groups or communities. (shrink)

Proponho comparar e aproximar as fundamentações normativas para o socialismo de Axel Honneth e John Rawls. Parto, para tanto, de alguns traços da teoria de Honneth desenvolvidos em seu escrito sobre socialismo e dos próprios contrastes estabelecidos por ele frente ao projeto de Rawls. Destrincho a comparação em duas frentes: a primeira, tratando do conteúdo normativo das noções de liberdade de ambos os autores, a segunda, tratando do que Honneth e outros autores da tradição da teoria crítica chamam de base (...) social ou imanente das teorias. Da primeira, concluo que o contraste estabelecido por Honneth entre o seu ideal de liberdade social e o ideal de liberdade encontrado na filosofia política de Rawls não encontra respaldo em uma análise acurada da proposta rawlsiana, e que a filosofia de Rawls também pode fornecer uma normatividade crítica para o Socialismo. Da segunda, concluo, a despeito da crítica de Honneth de que haveria uma deficiência ‘prático-política’ na filosofia de Rawls, que é possível encontrar na obra deste, de uma forma mais ou menos similar àquela do autor alemão, os três elementos que Honneth julga serem necessários para uma teoria crítica que não queira ser apenas uma crítica ‘puramente normativa’ da sociedade. (shrink)

Este trabalho busca discutir, a partir de dados obtidos em trabalho de campo etnográfico coletivo multissituado, elementos de uma cultura comunicacional dos torcedores no Brasil. Tradicionalmente tratados como coletivo, massa, povo ou multidão pelos meios de comunicação tradicionais, a abordagem proposta evidencia, nas falas dos próprios torcedores, uma compreensão sofisticada do universo afetivo, familiar, econômico e político que envolve o torcer por uma equipe de futebol no Brasil contemporâneo.

Abstrak: Filsafat telah memiliki perjalanan panjang dalam hubungannya dengan Kristianitas. Sumbangan filsafat untuk Kristianitas begitu banyak terutama dalam kaitannya dengan teologi. Tulisan ini meneliti soal integrasi filsafat dalam Kristianitas yang selama ini sering diperdebatkan. Periode apologi yang dimulai pada awal abad kedua sampai dengan pertengahan abad ketiga Masehi, memberikan suatu penjelasan konkrit untuk permasalahan ini. Melalui para apologet, yang sebelumnya adalah filsuf, bahkan mampu melangkah lebih jauh dalam penemuan kebijaksanaan yang sesungguhnya yang merupakan obyek dan tujuan filsafat. Bahkan mereka sampai (...) pada suatu pemikiran bahwa filsafat adalah ranah semai yang mempersiapkan filsafat yang sesungguhnya, yaitu Kristianitas. Berkat para apologet, filsafat menjadi bagian penting dalam Kristianitas, bukan saja di bidang teologi, tetapi juga di dalam ranah eksegese, hermeneutika dan terlebih-lebih di dalam hidup. Penulis Kristiani setelah periode apologi mengintegrasikan filsafat dalam tulisan dan di dalam rumusan iman. Berbagai terminologi filosofis yang diintegrasikan ke Kristianitas belum tergantikan sampai dengan saat ini. Kata-kata Kunci: Filsafat, filsuf, teologi, apologi, apologet, kebijaksanaan. Abstract: Philosophy is having a long journey in its relationship with Christianity. There is much influence of philosophy on Christian thinking, but especially on theology. This article researches the integrity of philosophy within Christianity, an integral relationship which has always been debated. During the period of the Apologies, which was begun at the beginning of the second century up to the middle of the third century, an important concrete solution to this debate was given. Through the Apology Fathers of the Church who previously were philosophers, had the capacity to go farther in finding real wisdom, which is the subject and the goal of all research in philosophy. They were able to reach a consideration that their philosophy was a field seed which had prepared for the real philosophy, which is Christianity. Through the apologies, philosophy created an important partnership with Christianity in the areas of theology and biblical exegeses, and even in hermeneutics and way of life. After the period of the Apology Fathers, Christian writers integrated philosophy in a certain way into their writings, even as a formula of faith. And some philosophical terminology, which was integrated into Christianity, could not be replaced after this time. Keywords: Philosophy, philosopher, theology, apology, apolog, virtue. (shrink)

Research and intervention involving primary prevention have grown dramatically in the past 10 years. However, little attention has been paid to ethical issues in primary prevention. This article proposes a framework for increasing awareness of such issues. The framework centers on explicating the contexts where prevention activities occur and the roles adopted by interventionists engaging in these activities. Several assumptions underlying primary prevention are stated, and ways of clarifying ethical issues are proposed.

国家社会科学基金项目获“高等学校优秀青年教师教学科研奖励计划资助”(TRAPOYT).

1. Sae sidae rŭl yŏrŏ gan saramdŭl -- 2. Ŏdum ŭi sidae.

Mal ŭi him -- Kŏjinmal ch'ammal kŭrigo ch'immuk.

Geography and religion -- Landscape of anxiety and fear -- Chinese cosmic space and places -- European sacred space and places -- A comparison with American Indian world-view -- Similar, yet different -- Apartness -- Order -- Wholeness and completion -- Sacred state -- Violence -- Ironies of piety -- God and morality -- From amoral energy to power for good -- Rise and fall of place specificity -- Traders and pilgrims -- Religious geography; or just human geography -- The (...) aesthetic sublime : vastness, place, and space -- Space vs. local place and custom -- Unbounded vastness and placelessness -- The aesthetic sublime : transiency and the eternal -- The ethical sublime : Buddhism -- The ethical sublime : Christianity -- Falling standard -- Geography and religion : fundamental questions -- From architectural and ritual to storytelling -- Community, self, and selflessness -- Placelessness and ethereality -- Religion of fear and privilege -- True religion -- Progress -- The ultimate test. (shrink)

Xunzi's philosophy provides a rich resource for understanding how ethical relationships between humans and nature can be articulated in terms of harmony. In this paper, I build on his ideas to develop the concept of reciprocal harmony, which requires us to reciprocate those who make our lives liveable. In the context of the environment, I argue that reciprocal harmony generates moral obligations towards nature, in return for the existential debt that humanity owes towards heaven and earth. This can be used (...) as a normative basis for an environmental ethic that enables humanity and nature to flourish together. (shrink)

Plausible principles on truth seem to yield contradictory conclusions about paradoxical sentences such as the Strengthened Liar. Those who take the contextualist approach, such as Parsons and Burge, attempt to justify the seemingly contradictory conclusions by arguing that the natural reasoning that leads to them involves some kind of contextual shift that makes them compatible. This paper argues that one cannot take this approach to give a proper treatment of infinite descending chains of semantic attributions. It also examines a related (...) approach taken by Gaifman and argues that it has the same problem. (shrink)

A plurality or plural object is a single object that is also many, and pluralitism is the thesis that there is such an object. This paper argues that pluralitism and closely related theses (e.g., the many-one identity thesis and the composition as identity thesis) violate logic. To do so, it formulates an approach to the logic and semantics of plural constructions that results in plural logic and relates treatments of plural constructions to accounts of natural number. And it gives a (...) critical examination of Frege’s views of numbers and plural constructions, and sketches the view of plural constructions as devices for talking about the many (as such), and an account of natural numbers as properties of a special kind, plural properties. (shrink)

BackgroundAging and type 2 diabetes mellitus are important risk factors for the development of cognitive deterioration and dementia. The objective of this research was to investigate the effects of an exercise intervention on cognitive function in older T2DM patients.MethodsEight literature databases were searched from inception to 20 January 2022. The researchers examined randomized controlled trials that evaluated the impact of exercise on the cognitive performance of older T2DM patients. The Cochrane risk-of-bias tool for RCTs was used to assess each study. (...) The quality of evidence was assessed using the GRADE approach. The mini-mental state examination, Modified MMSE, and Montreal cognitive assessment were used to evaluate the cognitive outcomes. We performed a subgroup analysis with stratification according to exercise intervention modality, duration, and cognitive impairment.ResultsFive trials were eligible, with a total of 738 T2DM patients. The combined findings revealed that exercise improved global cognitive function significantly. In the studies that were included, no relevant adverse events were reported.ConclusionExercise is beneficial in improving global cognitive function in older adults with T2DM. Studies with bigger sample sizes and higher quality are additionally expected to draw more definite conclusions.Systematic Review Registration[https://www.crd.york.ac.uk/PROSPERO/#recordDetails], identifier [CRD42022296049]. (shrink)

The underlying aim of this study was to investigate the impact of interpersonal injustice on emotional exhaustion and the three main facets of knowledge hiding, i.e., evasive knowledge hiding, playing dumb, and rationalized knowledge hiding. This study also investigates the moderating role of high-performance work stress in the relationship between interpersonal injustice and emotional exhaustion. A questionnaire was adopted to obtain data from 539 employees working in the telecom sector of China. The Smart-PLS software was used to analyze the data (...) through the aid of a structural equation modeling technique. The results revealed that interpersonal injustice had a positive and significant relationship with evasive knowledge hiding, playing dumb, and rationalized knowledge hiding. Interpersonal injustice also had a positive relationship with emotional exhaustion, and it was found that emotional exhaustion had a positive relationship with evasive knowledge hiding, playing dumb, and rationalized knowledge hiding. The results also revealed that emotional exhaustion mediated the relationship between interpersonal injustice and knowledge hiding. Moreover, it was also observed that high-performance work stress significantly but negatively moderated the relationship between interpersonal injustice and emotional exhaustion. Theoretically, this study made a valuable contribution by examining the impact of interpersonal injustice on knowledge hiding behavior. In terms of practical implications, this study would certainly aid the organizations to support a fair and just workplace culture that encourages knowledge sharing. (shrink)

This study examined the metaphorical expressions of death in Chinese quadrisyllabic idioms. Specifically, the research investigated the cultural connotations and implications conveyed through death-related idioms by analyzing metaphorical examples. Adopting the ‘Great Chain of Being’ framework (Lakoff and Turner, 1989), a total of 579 death-related idioms with metaphorical and euphemistic meanings were classified and examined. These idioms were further categorized based on the gender of the deceased as well as the initial metaphors and expressions employed. Our research findings highlight cultural (...) parallels evident in death-related idiomatic expressions. Both English and Chinese languages employ metaphors like “DEATH IS SLEEP” and “DEATH IS DEPARTURE.” These pervasive metaphors can be attributed to shared aspects of the human experience. Meanwhile, our findings also revealed a strong intertwining of metaphors and culture within death-related idioms, such that the metaphor “TO DIE IS TO FALL” is frequently used in Mandarin but is not as common in English. The metaphorical mapping mechanisms employed in these idioms reflect the Chinese way of projecting thoughts onto objects and highlight the unique features of the Chinese language. Chinese culture places great emphasis on social classes, relationships, and hierarchical structures. These notions are not only reflected in social etiquette and how one handles interactions, but are also evident in euphemisms and idioms associated with death. (shrink)

스페인 시인 씰로트의 상징사전을 토대로 국내외 문학작품을 예로 들어 주제별, 가나다순으로 수록한 문 학평론가의 상징사전.