The present study was aimed at gaining a broad opinion regarding bioethical reasoning amongst student fraternity. These students had been admitted to medical schools after completion of their high school . Ethnically all the students were of Indian origin though they belonged to a diverse socio-economic-cultural background. The mean age of students was 18 years and a total of 125 first year medical students were questioned in 1998 , using the questionnaire designed by Macer with some modifications. The observations revealed (...) the fact that even though fair amount of awareness regarding the wide perspectives of bioethics did prevail amongst many, yet some sense of ignorance was reflected as well. However, the respondents were divided on various sensitive issues like cloning, in vitro fertilisation etc. The results suggest enforcement of both individual and collective efforts to arouse the consciousness of students regarding bioethics and application of bioethical decision making to dilemmas posed by science and technology. (shrink)

The author of this article is the first woman Bishop in the Church of South India. Her article outlines the development of women’s ministry in India, from the influence of European missionaries in the nineteenth century, and through the union of traditions which led to the formation of the CSI. Women have traditionally served in auxiliary ministries, as Bible Women or deaconesses. The story is set against the context of deeply traditional cultures. The second half of the article relates the (...) author’s own journey through vocation and call to her present role, in which she experienced firsthand the difficulties that faced women seeking to answer a vocation to ministry. (shrink)

Contributed research papers on various aspects of Buddhist philosophy, doctrines and literature.

fusion theory challenges efforts to see theory as inhibiting by presenting an approach that is innovative, eclectic, and subtle in order to draw out competing and constellating ideas and opinions. This collected volume of essays examines fusion theory and demonstrates how the theory can be applied to the reading of various works of Indian English novelists.

The proteasome family of proteases comprises oligomeric assemblies of very different symmetry. In different sizes, it features ring‐like oligomers with dihedral symmetry that allow the stacking of further rings of regulatory subunits as observed in the modular proteasome system, but also less symmetric helical assemblies. Comprehensive sequence and structural analyses of proteasome homologs reveal a parsimonious scenario of how symmetry may have emerged from a monomeric ancestral precursor and how it may have evolved throughout the proteasome family. The four characterized (...) representatives—ancestral β subunit (Anbu), HslV, betaproteobacterial proteasome homolog (BPH), and the 20S proteasome—are outlasting cornerstones in the family's evolutionary history, each marking a transition in symmetry. This article contextualizes the evolutionary and functional key aspects of these symmetry transitions, explaining how they facilitated the diversification and concurrent evolution of independent proteolytic systems side by side, each with its customized network of auxiliary interactors. -/- . (shrink)