Automatic control of physiological variables is one of the most active areas in biomedical engineering. This paper is centered in the prediction of the analgesic variables evolution in patients undergoing surgery. The proposal is based on the use of hybrid intelligent modelling methods. The study considers the Analgesia Nociception Index to assess the pain in the patient and remifentanil as intravenous analgesic. The model proposed is able to make a one-step-ahead prediction of the remifentanil dose corresponding to the current state (...) of the patient. The input information is the previous remifentanil dose, the ANI variable and the electromyogram signal. Modelling techniques used are Artificial Neural Networks and Support Vector machines for Regression combined with clustering methods. Both training and validation were done with a real dataset from different patients. Results obtained show the potential of this methodology to calculate the drug dose corresponding to a given analgesic state of the patient. (shrink)

This work focuses on the application of machine learning techniques to assist the clinicians in the administration of analgesic drug during general anaesthesia. Specifically, the main objective is to propose the basis of an intelligent system capable of making decisions to guide the opioid dose changes based on a new nociception monitor, the analgesia nociception index. Clinical data were obtained from 15 patients undergoing cholecystectomy surgery. By means of an off-line study, machine learning techniques were applied to analyse the possible (...) relationship between the analgesic dose changes performed by the physician due to the hemodynamic activity of the patients and the evolution of the ANI. After training different classifiers and testing the results under cross validation, a preliminary relationship between the evolution of ANI and the dosage of remifentanil was found. These results evidence the potential of the ANI as a promising index to guide the infusion of analgesia. (shrink)

Metallothioneins (MTs) are ubiquitous proteins with the capacity to bind heavy metal ions (mainly Cd, Zn or Cu), and they have been found in animals, plants, eukaryotic and prokaryotic micro‐organisms. We have carried out a comparative analysis of ciliate MTs (Tetrahymena species) to well‐known MTs from other organisms, discussing their exclusive features, such as the presence of aromatic amino acid residues and almost exclusive cysteine clusters (CCC) present in cadmium‐binding metallothioneins (CdMTs), higher heavy metal‐MT stoichiometry values, and a strictly conserved (...) modular–submodular structure. Based on this last feature and an extensive gene duplication, we propose a possible model for the evolutionary history of T. thermophila MTs. We also suggest possible functions for these MTs from consideration of their differential gene expressions and discuss the potential use of these proteins and/or their gene promoters for designing molecular or whole‐cell biosensors for a fast detection of heavy metals in diverse polluted ecosystems. (shrink)

Introduction: Resilience is a multidimensional and dynamic construct associated with positive growth and the capacity to transform stressful and negative factors into opportunities of personal development and self-improvement when faced with difficult experiences. The resilience process of each individual integrates multiple analysis levels, which range from genetic-environmental interactions to a complex process of adaptation between the individual and his/her family, friends, co-workers, society, and culture.Objective: To determine whether resilience improves in students of occupational therapy when exposed for the first time (...) to practice placement education.Methodology: Quasi-experimental, prospective, observational, multi-center study with a sample composed of students from the Degree of Occupational Therapy of the public universities of Málaga and Castilla-La Mancha. Two weeks prior to the beginning of the practice education period, the participants completed a questionnaire that included sociodemographic data and the area of their internships. They were also given the Spanish version of the Connor-Davidson's resilience scale. All these instruments were also completed 1 week after the end of the clinical practice.Results: There were statistically significant differences between the variables that make up resilience and the different internship areas. On the other hand, there was a significant improvement of global resilience after the clinical practice period, in both women and men, when the internship area was not considered.Conclusions: The results show that resilient students are more optimistic and work to improve a situation beyond doing simply what is expected of them, knowing how to control their feelings. This is beneficial for students in practice education, since, during these, they face difficult situations that require a resilient pattern, which helps reduce stress and the burnout syndrome. (shrink)

Enlightening and entertaining, _Philosophical Tales_ examines a few of the fascinating biographical details of history’s greatest philosophers and highlights their contributions to the field. By applying the true philosophical approach to philosophy itself, the text provides us with a refreshing 'alternative history' of philosophy. Opens up new philosophical debate by applying the true philosophical approach to philosophy itself Provides summaries of the most celebrated and philosophically interesting tales, their backgrounds, and assessments of the leading players Explores philosophers and schools of (...) thought in one key philosophical text to supply a solid grounding in philosophical ideas and individuals Shakes some of the foundations of philosophy with the aim of encouraging the reinvigoration of philosophy itself. (shrink)

Enlightening and entertaining, _Philosophical Tales_ examines a few of the fascinating biographical details of history’s greatest philosophers and highlights their contributions to the field. By applying the true philosophical approach to philosophy itself, the text provides us with a refreshing 'alternative history' of philosophy. Opens up new philosophical debate by applying the true philosophical approach to philosophy itself Provides summaries of the most celebrated and philosophically interesting tales, their backgrounds, and assessments of the leading players Explores philosophers and schools of (...) thought in one key philosophical text to supply a solid grounding in philosophical ideas and individuals Shakes some of the foundations of philosophy with the aim of encouraging the reinvigoration of philosophy itself. (shrink)

Examen de afinidades y diferencias en la filosofía de dos cualificados representantes del Humanismo del siglo XII y XIV, Juan de Salisbury y Dante Alighieri respectivamente, a partir de un estudio comparado del Policraticus y De Monarchia; a la luz del proceso de secularización de la cultura y pensamiento europeos a fines del Medievo.Exam of affinities and differences in the philosophy, of them qualified representatives of the Humanism of the XII and XIV centuries, John of Salisbury and Dante Alighieri respectively, (...) through a compared study of Policraticus and De Monarchia; to the light of the secularization process of the culture and european thoughts at the end of the Medieval Age. (shrink)

Se estudia la relación entre la sátira culta de Juan de Salisbury y la sátira popular contemporánea de los goliardos, poniendo de manifiesto sus afinidades y diferencias.

Hacemos en el presente trabajo un pequeño recorrido a propósito de las manifestaciones o expresiones de ateísmo y materialismo, popular y culto, a fines del siglo XVIII y dos primeras décadas del siglo XIX, a partir, sobre todo, de los archivos inquisitoriales del Tribunal de Santiago de Compostela o Galicia. empleando una metodología mixta (historia conceptual, antropología cultural, historia de las ideologías, historia de la filosofía, etc.) y en base a fuentes documentales del siglo XIX tomadas del Archivo Histórico de (...) la Universidad de Santiago de Compostela (poco conocidas) o del Archivo Histórico Nacional de Madrid (inéditas), arqueológicamente, intentamos reconstruir 25 agitados años de la historia de la cultura gallega, centrándonos muy especialmente en la historia del pensamiento filosófico. (shrink)

Se habla de las traducciones de Aristóteles y Pseudo-Aristóteles en tierras gallegas o realizados por gallegos en la Edad Media; así como los problemas inherentes a toda operación de traducción en cualquier época y circunstancia. Nos centramos en Pedro Gallego, representante de la 3º generación de los traductores de la corte toledana de Alfonso X el Sabio, de quien fue amigo y confesor, aunque afincado en Murcia y obispo titular de la recién recuperada sede de Cartagena. Y pormenorizamos las distintas (...) secuencias en el traslado de una de las obras capitales de Aristóteles, que tanto interesó a los árabes, del árabe al latín, el Liber de animalibus, compendio de diversos trabajos naturalistas y de biología, que traduce nuestro autor natural de Ortigueira (mariña lucense). (shrink)

A comienzos del siglo XVII, se advierte una confluencia entre la corriente escéptica y el averroísmolatino en el seno del movimiento libertino de la edad clásica, como denuncia T. Campanella. Tratamosde explicar en el presente artículo porqué esto no fue posible en época anterior. Y el papel jugado porel «Galeno latino» de la Edad Media , con su crítica al pirronismo y la supuesta,para él, contaminación de las escuelas médicas helenísticas , en este proceso dedilación, retardo o aplazamiento de dicha (...) convergencia.At the beginning of the 17th century, a confluence between the sceptical tendency and the Latin Averroismis advised in the libertine movement of the classical age, so like Tommaso Campanella proclames.We try to explain in the present article why this was not possible in a previous time. Like the role playedby the «Latin Galen» , with its censure to the pyrrhonisme and the supposed, for him, contamination of the Hellenistic medical schools , in this process of delay. (shrink)

Este trabajo tiene como objetivo revelar el verdadero nombre de Finlay y la trascendencia de su firma a fin de salvaguardar cómo llega hasta hoy la autenticidad denominativa del científico. Para ello fue necesaria la revisión bibliográfica de diversas fuentes documentales. Destacan las Obras Completas del médico, artículos científicos de revistas indexadas de la nación y el exterior: Educación Médica Superior, Cuadernos de Historia de la Salud Pública, Biomédica, Acimed, Asclepio, entre otras; periódicos, así como entrevistas a especialistas de la (...) Casa Natal de Carlos J. Finlay. This work aims to real the true name of Finlay and the significance of his signature in order to safeguard its authenticity in present times. To this end, the bibliographic revision of several documentary sources was necessary. Revisions were made of his Complete Works, scientific articles indexed in national and foreign scientific journals, newspaper articles and interviews with specialists from the Carlos J. Finlay Birth House Museum. (shrink)

En los relatos de María, la madre de Jesús, encontramos un modelo de la realidad personal humana en el dinamismo de su realización como un continuo estar-dando-de-sí que muestra su desbordamiento como realidad educanda, realidad abierta. En otros relatos se muestra a mujeres como testigos del encuentro con Jesús después de su muerte, un testimonio que es recibido por el grupo de Jesús y corroborado por los varones de la comunidad para hacerlo llegar más allá de sus fronteras. En el (...) testimonio recibido y la acción compartida se muestran los cimientos de una sociedad que se construye en igualdad. (shrink)

La visión tradicional del pensamiento crítico (PC) fundada en un enfoque racionalista ha sido puesta en duda a partir de fines del siglo pasado por la ‘segunda ola’ del PC, la cual, a pesar de no ser un movimiento del todo definido, ha incluido aspectos como la imaginación, la creatividad y el trabajo cooperativo en su comprensión y en su aplicación a la enseñanza. Paralelamente, perspectivas actuales en psicología moral como el modelo ‘intuicionista social’ propuesto por Jonathan Haidt, representan un (...) desafío al modelo racionalista de la moral que suponen gran parte de las éticas normativas canónicas. Siendo que tanto el PC como el fundamento moral representan factores fundamentales en la enseñanza de ética, se hace explicito que esta última precisa también ser revisada. Es por ello que el presente trabajo analiza una perspectiva del PC alternativa a la tradicional basada en el potencial aporte de la metacognición y del modelo intuicionista social, con el fin de abrir nuevas vías de investigación para la actualización del fundamento moral que se supone en la enseñanza de ética. Para ahondar en ello, se ejemplificará la relevancia y aplicabilidad de la metacognición en la enseñanza de ética con situaciones vinculadas a la actual pandemia por Covid-19. (shrink)

Las estadísticas muestran que la tasa neta de escolarización en los estudios de grado en España aumenta significativamente. En esta investigación se pretende explorar la evolución de la cuenta de resultados y balance de aquellas empresas españolas de educación universitaria privada. Empleando los datos publicados en la base de datos SABI se han analizado las empresas con mayor volumen de facturación y total de activos. Como hallazgos principales se ha observado un incremento de la cifra de negocios y del resultado, (...) del orden del 40% y 20% respectivamente. No así la inversión en activos que se ha mantenido. (shrink)

BackgroundFor a long time, in sports, researchers have tried to understand an expert by comparing them with novices, raising the doubts if the visual search characteristics distinguish experts from novices. Therefore, the aim of the present study was to review and conduct a meta-analysis to evaluate the differences in visual search behavior between experts and novices in team sports athletes.MethodsThis systematic review with meta-analysis followed the PRISMA 2020 and Cochrane's guidelines. Healthy team athletes were included, which engaged in regular practice, (...) from any sex or competitive level, specifically classified a priori as expert or novice in the original research. We considered only research published in peer-reviewed journals, with no limitations regarding date or language. It was considered healthy team sport athletes engaged in regular practice. The scenarios could be in situ or film-based. The databases of EBSCO, PubMed, Scopus, SPORTDiscus, and Web of Science were used to perform the searches. The risk of bias was calculated through the RoBANS tool.ResultsFrom a total of 6,257 records, of which 985 were duplicates, titles and abstracts of 5,272 were screened, and 45 required full-text analysis. Of those, 23 were excluded due to not fulfilling the eligibility criteria regarding participants. In the end, 22 studies were selected, however, as two studies were part of the same trial and were analyzed conjointly.DiscussionExperts showed to be older and with more years of practice. The ability to distinguish experts from novices was not so clear regarding the variables analyzed. This could be due to the strategies chosen in each study, which were specific to each scenario, and when grouping all together, it was lost information within non-representative averages. The distinction between experts and novices was not clear, showing a lot of heterogeneity in the included studies. The expert classification itself may have been the conditioning aspect for these results, retaining the doubt and the need for more studies in the field.Systematic review registrationThe protocol was pre-registered in OSF. (shrink)

In April 2015, an international team of researchers announced the measurement, for the first time, of the first ionization energy of lawrencium, a superheavy element of atomic number 103. The experimental result, published in the prestigious scientific journal Nature, led to the reopening of a long-standing debate that concerns the elements that should be part of group 3 of the periodic table. The aim of this paper is to introduce a new line of argumentation to elucidate this problem.

There is no doubt that the use of Internet for purchasing products and services has constituted a crucial change in how people go about buying them. In the era of digital transformation, the possibility of accessing information provided by other users about their personal experiences has taken on more weight in the selection and buying processes. On these lines, traditional word-of-mouth has given way to electronic word-of-mouth, which constitutes a major social change. This behavior is particularly relevant in the services (...) area, where potential users cannot in advance assess what is on offer. There is an abundant literature analyzing the effects of eWOM on different variables of interest in this sector. However, little is known about the factors that determine eWOM. Thus, the main objective of the present paper is to analyze the impact of two variables on eWOM. Both of them are crucial for potential customers in the process of finding hotel accommodations and they can motivate people to make such comments. The results demonstrate that these variables truly have a significant impact on whether or not users make comments on line. Moreover, it proved possible to observe certain differences according to the profile of the tourist involved and the destination where the hotel is located. In the current changing environment, this information is of great use for hotel managers in order to design strategies according to the type of guest they wish to attract. (shrink)

La novela póstuma de Macedonio Fernández, Museo de la Novela de la Eterna es una obra paradigmática de la narrativa argentina. Su largo proceso de escritura desde 1904 y su publicación diferida en 1967 despiertan un interés en la historia de su recepción. El objetivo del presente trabajo es señalar algunas paradojas que surgen de las lecturas del texto y de cómo se ha interpretado su autonomía ficcional durante el contexto de su publicación –el boom–. La primera parte busca delimitar (...) la noción de “autonomía ficcional” a partir de las vanguardias, e indagar en su aplicación en Museo. La segunda examina la recepción de la novela entre la crítica latinoamericanista de los años sesenta para describir cómo se ha leído un texto que buscaba alcanzar la autonomía plena de la ficción en una época en que el compromiso político era clave entre los escritores latinoamericanos. (shrink)

Resumen: La novela póstuma de Macedonio Fernández, Museo de la Novela de la Eterna es una obra paradigmática de la narrativa argentina. Su largo proceso de escritura desde 1904 y su publicación diferida en 1967 despiertan un interés en la historia de su recepción. El objetivo del presente trabajo es señalar algunas paradojas que surgen de las lecturas del texto y de cómo se ha interpretado su autonomía ficcional durante el contexto de su publicación -el boom-. La primera parte busca (...) delimitar la noción de “autonomía ficcional” a partir de las vanguardias, e indagar en su aplicación en Museo. La segunda examina la recepción de la novela entre la crítica latinoamericanista de los años sesenta para describir cómo se ha leído un texto que buscaba alcanzar la autonomía plena de la ficción en una época en que el compromiso político era clave entre los escritores latinoamericanos. Abstract: The posthumous novel Museo de la Novela de la Eterna by Macedonio Fernández, is a paradigmatic book of Argentine narrative. His long writing process from 1904 and his deferred publication in 1967 arouses an interest in the history of its reception. Analyzing the impact and reading of Museo discover the evolution of its literary field. The aim of this article is to identify some paradoxes discovered when examining the insignificant interpretations of text, especially, regarding the tension between fictitious autonomy and its relation with the context in which is revised, the sixties. The first part seeks to delimit the definition acquired by the notion of "fictional autonomy" from the avant-garde movement, and investigate its application in Museo. The second one examines the reception of the novel in the sixties, that is, how to read a text that pursued the full autonomy of fiction at a time when political commitment was key for Spanish-American writers. (shrink)

RésuméDepuis les débuts de l'humanité, l'être humain s'est préoccupé de conserver les aliments en vue de les rendre plus longtemps comestibles. Au fil du temps, différentes méthodes pour préserver la nourriture ont été découvertes et perfectionnées, et ces techniques se trouvent décrites dans beaucoup d'œuvres. Ce travail décrit la connaissance des techniques de conservation qu'avaient les habitants de la péninsule ibérique ainsi que les développements qu'ils leur ont apportés. Il s'attache à étudier les divers procédés mis au point entre leieret (...) lexviesiècle, de façon à évaluer leur apport historique respectif. Les œuvres choisies et consultées sont : L.J.M. Columela,Los doce libros de Agricultura, Abū al-Jayr,Kitāb al-Filāḥa. Tratado de agricultura, Ibn Baṣṣāl,Kitāb al-Filāḥa. Libro de agricultura, Ibn al-ʿAwwām,Kitāb al-Filāḥa. Libro de Agricultura, Ibn Luyūn,Kitāb al-Filāḥa. Tratado de Agricultura, Alonso de Herrera,Agricultura general. (shrink)

From the standpoint of the school settings, sport participation constitutes a key strategy concerning the manifestation of positive behaviors that result from the development of personal and social responsibility. Based on the TPSR model, the goal of this study was to evaluate the effects of an intervention geared toward teaching life skills through sport to youngsters who had been committed. The participants were evaluated before and after the intervention. After the initial evaluation, they were randomly assigned to the experimental and (...) control groups. The experimental group took part in the community football program, while the control group attended physical education classes not based on the TPSR model. The experimental model consisted of 3 weekly sessions over the course of 6 weeks, which totaled 18 sessions. This investigation supplied empirical evidence concerning the potential of community sport programs in the teaching and development of life skills deemed necessary for an adequate reintegration of such at-risk youngsters. The model was shown to be valid both in stimulating changes of attitudes and in promoting the adherence to socially positive behaviors. The effectiveness of the model, as well as its unique approach, make its application attractive to both the youngsters and the professionals. This program facilitates the training of youngsters to act, in the sense of promoting both their autonomy and the acquisition of a system of ethics and moral values within a culture of responsibility for how decisions affect the individual and the community. Finally, this intervention generated empirical support in favor of the argument that sport constitutes a unique opportunity within the educational process to establish values, beliefs, attitudes, and practical habits pertaining relationships and cooperation that generate social responsibility in individuals. (shrink)

Neuroscience influences education, and these two areas have converged in a new field denominated “Neuroeducation.” However, the growing interest in the education–brain relationship does not match the proper use of research findings. In 2007, the Organization for Economic Cooperation and Development warned of the misunderstandings about the brain among teachers, labeling them as neuromyths. The main objective here is to observe the prevalence of the neuromyths in educators over time. After two decades of publications of research on neuromyths among in-service (...) or prospective teachers, this work presents a systematic scientific review. To select the articles, we used the words: “teachers,” “preservice teachers,” “neuromyths” combined with the Boolean data type “and.” The search was filtered according to the following criteria: identifiable author, written in English, Spanish, French, Italian, or Portuguese, word neuromyth in title, abstract, or keywords, research with a participant's survey, sample focused on educators, peer-review publication index in JCR, SJR, or ESCI. The documents were found through Web of Science, Scopus, PubMed, Dialnet, ProQuest, EBSCO-host, and Google Scholar. After the search, 24 articles were identified as being of sufficiently high quality for this systematic review. This result highlights that neuromyths are still the subject of attention almost two decades after their definition. The findings present neuromyths as the consequence of a lack of scientific knowledge, a communicative gap between scientists and teachers, and the low-quality information sources consulted by teachers. In addition, the data on protectors and predictors of neuromyths is inconsistent. There is also no standard scientific methodology nor a guideline to determine a new neuromyth. The results show the need to improve the scientific content in higher education and the importance of in-service teacher training. This research justifies the requirement for university professors to be active researchers and to establish a close link with educators from other fields and levels. Neuroeducation will be the bridge that unites scientific knowledge and practical application in education, with a rigorous, standard method for the entire scientific-educational community. (shrink)

The article aims to summarize the literature about the profile of risk of orthorexia in athletes using the ORTO-15 questionnaire. The search was performed at PubMed, Embase, Web of Science, and Sport Discus databases, using the terms “orthorexia” AND “athletes” with the respective entry terms. A multistage process of selection followed the PRISMA 2020 recommendation. A total of 688 articles were identified, and six studies were available for the final process. The prevalence of risk for orthorexia was assessed by the (...) articles by the ORTO-15 questionnaire and ranged between 38 and 35 points. The comparison between male and female athletes and, athletes and non-athletes was not significant in the six articles. In conclusion, the review highlights that athletes from different sports, included in the review, do not present a risk of orthorexia nervosa considering the cutoff of 40 points, but not 35 points. Also, athletes present the same orthorexic behavior compared to non-athletes, demonstrating that orthorexia is an issue that needs to be considered in the general population. Moreover, a special focus should be given on the ORTO-15 questionnaire, about the sensitivity to diagnose the prevalence of orthorexia, especially in athletes. (shrink)

International criminal law (ICL) has traditionally overlooked sexual and gender-based violence (SGBV) and struggles to understand it. Prosecutions have been largely inefficient and not reflective of gender harms. The Rome Statute requires interpreting SGBV as a social construction (article 7(3)), in consistency with international human rights law (IHRL) and without discrimination (article 21(3)). There is, however, little guidance to implement these approaches. This article argues that intersectionality, an IHRL-based approach that reveals compounded discrimination, is an efficient tool to interpret SGBV (...) and, therefore, should be integrated in ICL. The article traces the origins of intersectionality in feminism and its recognition by IHRL dealing with violence against women. It establishes the applicability of intersectionality in ICL that it demonstrates with a comparative analysis of the Lubanga and Ntaganda cases. The findings show that intersectionality suits ICL’s specific needs which allows labelling and explaining some of those contributions throughout the judicial process. (shrink)

La mentoría como programa de formación en el inicio de la vida profesional del docente principiante se presenta como una oportunidad para la mejora de la calidad de las instituciones educativas y de sus agentes. Al mismo tiempo, revierte sobre la comunidad y el territorio donde se ubica. En contextos reconocidos como vulnerables se necesitan agentes educativos vocacionales y con un alto nivel de resiliencia, y con una meta clara: formar a personas plenas que contribuyan con su sentir, ser y (...) hacer al desarrollo de la comunidad en la que habitan. (shrink)

El artículo analiza el trabajo de apropiación crítica llevado a cabo por Enrique Dussel de la obra de F. W. J. Schelling. Es interesante analizar, desde el marco aportado por la Historia de las Ideas en América Latina, cómo el filósofo de la liberación entiende y resignifica las categorías filosóficas desarrolladas por el filósofo romántico. El artículo se propone identificar los supuestos epistemológicos y metodológicos mediadores en este trabajo de interpretación categorial que le permite al filósofo argentino, entre otros aportes, (...) articular el método analéctico, método a partir del cual es posible proponer una filosofía que se aparta de la dialéctica de lo Uno y puede conceptualmente llegar al otro. (shrink)