ObjectiveTo investigate the short-term effect of music therapy combined with binaural frequency difference therapy on patients with consciousness disorder.Materials and methodsNinety patients with definite diagnosis of disorders of consciousness were selected. These patients were randomly divided into control group, experiment 1 group and experiment 2 group, with 30 patients in each group. The control group was treated with routine clinical treatment and rehabilitation. In experiment 1 group, music therapy was added to the control group. In experimental group 2, music therapy (...) combined with binaural α frequency difference therapy was added to the control group. All patients were assessed before and after 30 treatments. The assessment items included Glasgow Coma Scale, Coma Recovery Scale revised, electroencephalogram, upper somatosensory evoked potential, and brainstem auditory evoked potential.ResultsBefore treatment, there were no significant differences in GCS score, CRS-R score, USEP, BAEP, and EEG scores among the three groups. After 30 times of treatment, GCS score, CRS-R score, USEP, BAEP, and EEG scores in 3 groups were significantly higher than those before treatment. And the consciousness rate of experimental group 2 was better than experimental group 1, experimental group 1 was better than the control group and the difference was statistically significant.ConclusionMusic therapy combined with binaural α frequency difference therapy is more effective in stimulating DOC patients. (shrink)

We are of the opinion that there is also identity between erroneous thinking and existence. Our opinion is based on the following facts.

Background:When the contagious COVID-19 spread worldwide, the frontline staff faced unprecedented excessive work pressure and expectations of all of the society.Objective:The aim was to explore healthcare workers’ stress and influencing factors when caring for COVID-19 patients from an altruistic perspective.Methods:A cross-sectional, descriptive study was conducted in a tertiary hospital during the outbreak of COVID-19 between February and March 2020 in Wuhan, the capital city of Hubei province in China. Data were collected from 1208 healthcare workers. Descriptive statistics and multiple linear (...) regression were used to analyze the data.Ethical considerations:Research ethics approval (with the code of TJ-IRB20200379) was obtained from Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology. Written informed consent was also received from participants.Results:Less than 60% of participants chose moderate or severe stress on all stressors, indicating a low stress level among healthcare workers. The main source of stress among frontline healthcare workers caring for COVID-19 patients came from the fear of being infected, the fear of family members being infected, and the discomfort caused by protective equipment. Frontline staff who were nurses, were married, and had worked more than 20 days suffered higher stress, whereas rescue staff showed lower stress.Conclusion:The healthcare workers caring for patients with COVID-19 had low stress level, although they still had the fear of being infected or uncomfortable feeling caused by personal protective equipment. A low stress level among healthcare workers indicated their professional devotion and altruism during COVID-19 epidemic. Medical institutions and the government should continue to strengthen infection prevention measures and provide more comprehensive care involving families of frontline healthcare workers, especially nurses and married staff. It will be a lesson to other countries that awaking healthcare workers’ inside motivation and providing necessary support from government and society were significant. (shrink)

Based on the existing financial system risk models, a set of time-lag financial system risk models is established considering the influence brought by time-lag factors on the financial risk system, and the dynamical behavior of this system is analyzed by using chaos theory. Through Matlab simulation, the bifurcation diagram and phase diagram of time-lag risk intensity and control intensity are plotted. The analysis shows that this kind of time-lag financial system risk model has complex dynamic behavior, different motion states will (...) appear when different parameter values are selected, and the time-lag risk intensity parameter also has a very strong influence on the system motion. To ensure the operation of the financial system in a stable state, measures with certain delay effects must be taken to control the risk and to choose the appropriate time-lag control intensity, and too much or too little time-lag control intensity is not conducive to the benign operation of the system. (shrink)

This study examines the relationship among the employees–organization pro-environmental values fit, supervisors’ PEVs and employees’ pro-environmental behaviors. Informed by the PEB, organizational values and employee–organization fit literature, we propose and test hypotheses that under egoistic, altruistic and biosphere-value orientations, E–O PEVs fit versus non-fit have significant effects on employees’ private-sphere PEB and public-sphere PEB, identifying supervisors’ PEVs as a moderator. An empirical investigation indicates that the effect of E–O PEVs fit on employees’ private-sphere PEB and public-sphere PEB varies as the (...) value orientation differs. More specifically, under the context of altruistic and biosphere-value orientations, if the organizational PEVs do not match the employees’ PEVs, especially when the former exceeds the latter, employees’ PEB will rise as the organizational PEVs increase. As for egoistic value orientation, when organizational PEVs exceed employees’ PEVs, not only will public-sphere PEB stop decreasing and tend to stabilize, but also private-sphere PEB will rise to a slight degree. Furthermore, compared with altruistic and biospheric values dimensions, supervisors who promote egoistic PEVs will have a more significant effect on the relationship between global E–O PEVs fit and employees’ PEB. Finally, we suggest that the goals of an organization and its supervisors need to be combined within the actual situation of Chinese corporations to truly implement corporate green practices by balancing the profit goal and the environmental goal. (shrink)

The rapid development of digital technologies has transformed the world but can be a double-edged sword. We study the interaction of important variables that affect individual news reporters’ performance in which digital technology is the dominant feature. A multilevel model illustrates how transactive memory and job competence affect individual performance. The empirical study includes data from 19 teams of news reporters and 211 valid survey responses, applying hierarchical linear modeling to analyze the data. The results indicate that transactive memory and (...) technology competence help to improve a reporter’s job performance. More importantly, teamwork competence fully mediates the relationships. Our findings thus suggest that teamwork competence is the core skill. Neither technology competence nor transactive memory alone translates directly into enhanced individual performance. (shrink)

Along with urban development globally, the NIMBY crisis has been a complex social problem, which requires urgent remedial action. The inevitable management of Municipal Solid Waste has been one of the toughest risk management tasks in the worldwide modernization process. At present, certain fuzzy and unstructured results and methods have been formed for MSW-NIMBY crisis response, mainly focusing on the sociology and politics which scatter in complex and sensitive reports and news. Aiming at enhancing the effectiveness of data mining from (...) specific sparse text of MSW-NIMBY crisis, an improved knowledge extraction method is developed. Through rule-based text mining and complex network analysis, the Entity Relationship network of MSW-NIMBY crisis is reconstructed. Meanwhile, a novel transitivity for relationship between entities in semantic analysis is proposed to improve the feasibility and accuracy of information extraction. Characteristics and regularity of MSW-NIMBY crisis evolution and experience of crisis governance could be identified effectively. Results show that knowledge integration and ER transitivity can enhance knowledge recognition and major other factors, which could help formulate the governance strategies of NIMBY crisis from academic texts. (shrink)

This article investigates the structure of trust in China and compares it with the U.S., using the 2000 and 2005 waves of the World Value Survey (WVS). We analyze two dimensions of trust - trust in people and trust in major companies. It is found that the level of trust has remained stable in China within the 5-year period. On the other hand, trust in major companies has declined dramatically in U.S. while trust in people has increased slightly. The structure (...) of trust in companies is different from trust in people. For both countries, individuals with higher education tend to have a higher level of trust. Individuals who are divorced tend to have lower trust in people. Individuals who think that other people are fair are more likely to trust in people. Preference for competition has a positive effect on trust in major companies. On the other hand, some differences between the two countries are observed. Perception of fairness does not affect trust in major companies in China, while it has a positive effect in U.S. in year 2006. Preference for equality has a negative effect on trust in major companies in U.S. but no significant effect in China. The pattern of trust and its changes over time may reflect differences in market conditions in the two economies. (shrink)

To solve the problem of user privacy disclosure caused by attacks on anonymous areas in spatial generalization privacy protection methods, a K and P Dirichlet Retrieval method based on k-anonymity mechanism is proposed. First, the Dirichlet graph model is introduced, the same kind of information points is analyzed by using the characteristics of Dirichlet graph, and the anonymous set of users is generated and sent to LBS server. Second, the relationship matrix is generated, and the proximity relationship between the user (...) position and the target information point is obtained by calculation. Then, the private information retrieval model is applied to ensure the privacy of users’ target information points. Finally, the experimental results show that the KPDR method not only satisfies the diversity of l 3 / 4, but also increases the anonymous space, reduces the communication overhead, ensures the anonymous success rate of users, and effectively prevents the disclosure of user privacy. (shrink)

Previous research has indicated that parenting factors affect the risk of maladaptive psychological outcomes, and that positive parenting is a prospective risk factor for maladaptive psychological outcomes. However, the mechanisms underlying the relationships between positive parenting, mindfulness, and maladaptive psychological outcomes remain unknown, as do the processes that mediate the effect of positive parenting on maladaptive psychological outcomes in adolescents. The objective of the present study was to investigate the longitudinal relationship between positive parenting, mindfulness, and maladaptive psychological outcomes in (...) middle school students, as well as the mediating effect of mindfulness in the relationships between positive parenting and depression, aggression, and suicidal ideation. In this study, 386 middle school children were tested three times over a period of 6 months. Positive parenting was assessed at Time 1, mindfulness at Time 2, and depression, aggression, and suicidal ideation at Time 3. Using structural equation modeling, positive parenting was revealed to be longitudinally associated with mindfulness and negatively associated with maladaptive psychological outcomes. More crucially, mindfulness mediated the relationship between positive parenting and maladaptive psychological outcomes. This research provides important insights into how to effectively decrease adolescent maladaptive psychological outcomes and highlights the importance of teaching mindfulness to youths. (shrink)

Background Caring behaviour is critical for nursing quality, and the clinical internship environment is a crucial setting for preparing nursing students for caring behaviours. Evidence about how to develop nursing students’ caring behaviour in the clinical environment is still emerging. However, the mechanism between the clinical internship environment and caring behaviour remains unclear, especially the mediating role of moral sensitivity and the moderating effect of self-efficacy. Research objective This study aimed to examine the mediating effect of moral sensitivity and the (...) moderating function of self-efficacy on the association between the clinical internship environment and caring behaviours. Research design A cross-sectional design used acceptable validity scales. The hypothesised moderated mediation model was tested in the SPSS PROCESS macro. Participants and research context This survey collected data from 504 nursing students in an internship at a teaching hospital in Changsha, China. Ethical considerations This study was pre-approved by the ethics committee of the medical school (No. E2022210). Informed consent was obtained from all students. Results The clinical internship environment ( B = 0.450, 95% CI = [0.371, 0.530]) and moral sensitivity ( B = 1.352, 95% CI = [1.090, 1.615]) had positive direct effects on nursing students' caring behaviours. Clinical internship environment also indirectly influenced students’ caring behaviours via moral sensitivity ( B = 0.161, 95% CI = [0.115, 0.206]). In addition, self-efficacy played a moderating role between the clinical internship environment and caring behaviours ( B = 0.019, 95% CI = [0.007, 0.031]), as well as the relationship between the clinical internship environment and moral sensitivity ( B = 0.006, 95% CI = [0.003, 0.010]). Conclusion Moral sensitivity mediates the effect of the clinical internship environment on caring behaviour, and self-efficacy strengthens both direct and indirect effects. This study emphasises the importance of self-efficacy in developing moral sensitivity and caring behaviours in nursing students. (shrink)

What is feminist philosophy? A difficult question for feminist scholars in China. Women's studies in the Chinese mainland are characteristically policy‐oriented, geared to practical concerns and moral urgency. Empirical research projects engage many pressing social issues related to the changing situation of women in a rapid marketification of society and commercialization of culture since the post‐1978 reform movement. Here are some examples: migrant female workers and their working conditions in the urban centers; the impact of rural industrialization on women in (...) the countryside: discrimination against women in employment as well as in other aspects of social life; marriage and sexual relations. What follows in this article however, represents an effort to identify and categorize trends in emerging feminist theories. The main questions that might be seen as in one way or another philosophical are located in the historical context of the transformation of Chinese socialism. As we have only very limited access to publications in Hong Kong and Taiwan, to avoid mispresentation we regret that we cannot discuss the feminist work developed in these areas. (shrink)

Professionals transitioning into a workplace face the challenge of socializing into their new working communities. One important factor in this process is humor. We present a case study of how a newcomer transitioning towards integral status interacts with the use of humor in her new workplace. Using the Communities of Practice framework, we examine workplace discourse collected from a new recruit, Emma, and her colleagues in a Hong Kong firm. The analysis portrays a picture of how humor is a critical (...) element as Emma negotiates relationships with other colleagues and works towards her assigned tasks. Findings suggest that humor can be an indicator to newcomers of appropriate or inappropriate behavior. Humor can be used for newcomers’ integration into the workplace; humor can be used by integral members to mold newcomers into the normative ways of doing things. We argue that humor may be used as a regulating and coping mechanism in workplace socialization. (shrink)

Based on the social identity theory, the relationship and influencing mechanism between high-performance human resource practices and employees’ voice behavior were explored by constructing a moderated mediation model, and the relationship between the field of human resources and the field of organizational behavior was also established. Through 1,178 paired samples of supervisor-employee survey and multilevel linear model analysis technology, it was found that HPHRPs had a positive impact on employees’ voice behavior; perceived insider status played a mediating role between HPHRPs (...) and voice behavior; voice efficacy played a moderating role between perceived insider status and voice behavior; and voice efficacy played a mediating role in the relationship between “HPHRPs-perceived insider status-voice behavior.”. (shrink)

The self-interest paradigm predicts that unethical behavior occurs when such behavior benefits the actor. A recent model of lying behavior, however, predicts that lying behavior results from an individual''s inability to meet conflicting role demands. The need to reconcile the self-interest and role conflict theories prompted the present study, which orthogonally manipulated the benefit from lying and the conflicting role demands. A model integrating the two theories predicts the results, which showed that both elements — self benefit and role conflict (...) — influenced lying, separately and interactively. Additionally, the relative strength of the roles in conflict affected their level of influence. Theoretical and practical implications are discussed. (shrink)

Objectives: The corona virus disease-2019 pandemic spread globally, and we aimed to investigate the psychosocial impact on healthcare workers in China during the pandemic.Methods: In this systematic review and meta-analysis, we searched seven electronic databases for cross-sectional studies on psychosocial impact on HWs in relation to COVID-19 from January 1, 2020 to October 7, 2020. We included primary studies involving Chinese HWs during the pandemic, and data were extracted from the published articles. Our primary outcome was prevalence of anxiety, depression, (...) and stress disorders. We pooled prevalence value with their 95% confidence interval using random effect models and assessed study quality on the basis of an 11-item checklist recommended by the Agency for Healthcare Research and Quality. The study protocol was registered in PROSPERO.Results: We identified 25 articles comprising a total of 30,841 completed questionnaires and 22 studies for meta-analysis. The prevalence of anxiety, depression, and stress disorders was 34.4%, 31.1%, and 29.1% for HWs. The pooled prevalence of anxiety disorders for HWs from late January to early February was 46.4%, significantly higher than those in mid-term February and after late February. The pooled prevalence of depression disorders for HWs from late January to early February was 46.5%, significantly higher than those in mid-term February and after late February. HWs working in Hubei Province had a higher prevalence of anxiety and a lower prevalence of depression than those working in other regions. Nurses had a higher prevalence of anxiety and depression than other HWs.Conclusions: About one-third of HWs in China suffered anxiety, depression, and stress at the early epidemic of COVID-19. HWs in Hubei Province, especially nurses, had a higher prevalence of psychological disorders. During the pandemic, a negative psychological state may persist in a proportion of Chinese HWs, fluctuating with the control of the pandemic. The long-term impact should continue to be observed. Attention should be paid to HWs for their psychological impact due to the pandemic.Systematic Review Registration: The study protocol was registered with PROSPERO. (shrink)

This article addresses the seemingly paradoxical proliferation of coded systems designed to guarantee our safety and crises that endanger us. These two phenomena, it argues, are not opposites but rather complements; crises are not accidental to a culture focused on safety, they are its raison d'être. Mapping out the temporality of networks, it argues that crises are new media's critical difference: its exception and its norm. Although crises promise to disrupt memory – to disturb the usual programmability of our machines (...) by indexing ‘real time’ – they reinforce codes and coded logic: both codes and crises are central to the production of mythical and mystical sovereign subjects who weld together norm with reality, word with action. Codes and states of exception are complementary functions, which render information and ourselves undead. Against this fantasy and against the exhaustion that crisis as norm produces, the article ends by arguing that we need a means to exhaust exhaustion, to recover the undecidable potential of our decisions and our information through a practice of constant care. (shrink)

This paper studies the state of charge estimation of supercapacitors and lithium batteries in the hybrid energy storage system of electric vehicles. According to the energy storage principle of the electric vehicle composite energy storage system, the circuit models of supercapacitors and lithium batteries were established, respectively, and the model parameters were identified online using the recursive least square method and Kalman filtering algorithm. Then, the online estimation of SOC was completed based on the Kalman filtering algorithm and unscented Kalman (...) filtering algorithm. Finally, the experimental platform for SOC estimation was built and Matlab was used for calculation and analysis. The experimental results showed that the SOC estimation results reached a high accuracy, and the variation range of estimation error was [−0.94%, 0.34%]. For lithium batteries, the recursive least square method is combined with the 2RC model to obtain the optimal result, and the estimation error is within the range of [−1.16%, 0.85%] in the case of comprehensive weighing accuracy and calculation amount. Moreover, the system has excellent robustness and high reliability. (shrink)

Out of 288 Hong Kong cancer patients, 92.3% include themselves in decision-making, 71% prefer joint decision-making: with family, with doctor, with doctor plus family, with family minus doctor, and with doctor minus family. <5% want decision-making by “doctor-alone” and <1% desire decision-making by “family-alone”. Harmony, communication and responsibility are reasons for family participation. Most patients prefer “specialist” for information, followed by “family”, “friends”, and “GP”. Trust in doctors and prospects for controlling/curing disease are important factors in decision-making. Patients want to (...) participate and be listened to rather than make decisions. Doctors should not disclose information to family without patients’ permission, nor withhold information from patient [End Page 109] on family’s request. Only 25% of patients have discussed post-competent treatment with others and 7% have heard of Advance Directive ; 24% refuse to discuss it. After AD has been explained to them, 66% remain reluctant to sign one, preferring to leave oral instructions or appoint family as proxy decision-makers. The family’s decision-making role increases when patients become incompetent. The top reason for signing AD is to receive preferred post-competent treatments, and for not signing it, difficulty with making a prospective decision. The implications of these findings will be discussed. (shrink)

No apology, I imagine, is necessary for the appearance of this translation\nof Marx's "Misere de la Philosophic" On the contrary it is strange\nthat it should not have been published in England before, anu that\nthe translation of his monumental work, the "Capital," tardy as that\nwas, should have yet been made before that of a work which was originally\npublished some twenty years before "Capital" first appeared.\n\n\nIt may be that the translators and editors of the latter work were\nof opinion that in view of (...) the comprehensiveness of "Capital," a\npublication of an English edition of the "Misere de la Philosophic"\nwould be a work of supererogation. Or it may be that they thought\na book so distinctly French—as the "Capital" may be said to be distinctly\nEnglish—and which was, further, exclusively a criticism of a work\nof Proudhon's little known in England—would have slight interest\nfor English readers. On the other hand, the groundwork of the theories\nso fully elaborated in "Capital," apart from its exhaustive analysis\nof the capitalist system of production and distribution, will be\nfound in "Misere." In addition, there are several subjects—notably\nthat of rent—dealt with in this volume which are barely touched upon\nin the single book of " Capital " which has been translated into\nEnglish.\n\n\nMarx's criticism of Proudhon's theory that " the time which is necessary\nto create a commodity indicates exactly its degree of utility," so\nthat " the things of which the production costs the least time are\nthe things which are the most immediately useful," has been matched\nby H. M. Hyndman's crushing refutation of the theory of Final Utility.\nThe subject of rent, too, has been fully dealt with by the latter\nin the same book, " The Economics of Socialism," published, as the\nauthor says, in the hope of furnishing " the rapidly-increasing number\nof students of sociology with a concise and readable statement of\nthe main theories of the scientific school of political economy founded\nby Karl Marx and Friedrich Engels." Neither of these facts, however,\nnecessarily detracts from the value of this older work of Marx's.\nOn the question of rent, after reviewing the Ricardian theory and\nthe many objections which present themselves to that theory, Hyndman\nsays: " It seems, therefore, that a wider definition of the rent\nof land under capitalism is needed than that given by Ricardo, and\nthe following is suggested: — Rent of land is that portion of the\ntotal net revenue which is paid to the landlord for the use of plots\nof land after the average profit on the capital embarked in developing\nsuch land has been deducted." On the question of confiscating rent\nhe says it " would not affect the position of the working portion\nof the community unless the money so obtained were devoted to giving\nthem more amusement, to providing them with better surroundings and\nthe like. ... In fact, the attack upon competitive rents is merely\na capitalist attack. That class sees a considerable income going\noff to a set of people who take no part in the direct exploitation\nof labor; and its representatives are naturally anxious to stop this\nleakage, as they consider it, and to reduce their own taxation for\npublic purposes by appropriating rent to the service of the State.\nThat is all very well for them."\n\n\nOn this point Marx says: " We can understand such economists as Mill,\nCherbulliez, Hilditch and others, demanding that rent should be handed\nover to the State to be used for the remission of taxation. That\nis only the frank expression of the hate which the industrial capitalist\nfeels for the landed proprietor, who appears to him as a useless\nincumbrance, a superfluity in the otherwise harmonious whole of bourgeois\nproduction."\n\n\n" Rent," says Marx, " results from the social relations in which exploitation\nis carried on. It cannot result from the nature, more or less fixed,\nmore or less durable, of land. Rent proceeds from society and not\nfrom the soil."\n\n\nThe criticism of Proudhon's appreciation of gold and silver as the\nfirst manifestation of this theory of " constituted value" should\nbe interesting reading to those admirers of the French Anarchist\nwho yet profess their profound detestation of money and its function.\nSo, too, should his declaration against strikes and combinations\nof workmen. In this we see once more how extremes meet. This declaration\nof Proudhon's would not be out of place in the organ of the Liberty\nand Property Defence League.\n\n\nIn this matter of trade union combination, Marx was scarcely accurate\nin his perception of its development. He clearly did not foresee\nthat the great English trade unions would become fossilised, as it\nwere; and that instead of being a revolutionary force they would\nbecome a reactionary mass, opposing the progress of the mere proletarian\noutside their ranks, as they have done. With the spread of Socialist\nideas among them, however, their exclusive character is being modified,\nand they may even yet take that place in the revolutionary working-class\nmovement which Marx anticipated they would occupy. Given this change\nof attitude, the development must inevitably be along the lines he\npredicted. We are seeing "in face of constantly united capital, the\nmaintenance of the association [becoming] more important and necessary\nfor them than the maintenance of wages," and, further, that the combinations\nof capital are forcing the trade unions to that point where "association\ntakes a political character."\n\n\nIt is scarcely necessary to point out that in this work, written in\n1847, some words have a meaning quite other than that which they\nbear to-day. Thus, for instance, the words "Socialists" and "Socialism,"\nwhere they occur, refer to the utopians—who formulated theories of\na social system independent of the industrial evolution— and to these\ntheories themselves.\n\n\nIn most cases the numerous quotations have been verified and reproduced\nin the original. In some instances, however, they are summaries rather\nthan quotations, and appear ^is translated.\n\n\nA translation jn* necessarily an imperfect presentation of the thoughts,\nideas, and conclusions of the author. In this work I have endeavored\nto adhere as closely as possible to the form and letter, as well\nas the spirit of the original, and to this the indulgent reader is\nasked to ascribe such faults of language as would otherwise merit\nhis censure. (shrink)

The green development level reflected in the green finance index and the evaluation of the degree of green development in smart cities have important practical effects on economic transformation. For promoting the transformation and upgrading of finance, we select 2013–2019 data and construct a distributed lag model to analyse the important role played by green finance and financial technology in the construction of smart cities. In the paper, we find green finance promotes the construction of smart cities, and only it (...) will not appear until nine months late. Financial technology has an opposite impact on the construction of smart cities, this is mainly because the research and marketization of financial technology are higher, and the cost is also higher. This influence will appear in the next 14 months. (shrink)

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

English summary: The debate regarding the true essence of nature that took place during the earlier part of the modern period is known to have had a great influence on the subsequent development of the natural sciences. One of the main arguments was the dispute about das wahre Kraftmass, the true measurement of force and mass between Leibnizians and Cartesians. Today the dispute is often considered superfluous since force is in itself a metaphysical concept. There are really is no empirical (...) criteria on which to base a mathematical formulation. Chun- Fa Liu believes that the dispute was rooted in the metaphysical theory of nature. Differences of opinion didn't only spring from the evaluation of nature using mathematics, but from the understanding of the concept of force and thus from metaphysical insights into nature in general. Liu argues that Leibniz's insights into nature were much more detailed, meaning metaphysically better defined than those of the Cartesians. This approach makes the controversy not a nonsensical linguistic argument but rather more a dignified, metaphysically profound dispute. German description: Die Kontroversen um das wahre Wesen der Natur in der fruheren Neuzeit haben bekanntlich grossen Einfluss auf die spatere Entwicklung der Naturwissenschaft. Eine der wichtigsten Debatten war der Streit um das Kraftmass zwischen den Leibnizianern und Cartesianern. Er wird heute ofter als unsinnig bezeichnet, denn Kraft ist an sich ein metaphysischer Begriff. Es gibt eigentlich kein empirisches Kriterium fur eine mathematische Formulierung. Chun-Fa Liu vertritt die Ansicht, dass jene Uneinigkeit auf die metaphysische Theorie der Natur zuruckgefuhrt werden muss. Der Meinungsunterschied liegt nicht allein in der Berechnung der Natur durch Mathematik, sondern im Verstandnis des Kraftbegriffs und damit in der metaphysischen Einsicht der Natur uberhaupt. Liu argumentiert, dass die Leibnizsche Einsicht in die Natur viel tiefer, d. h. metaphysisch besser begrundet ist, als die der Cartesianer. So betrachtet ist die Kontroverse kein unsinniger Wortstreit, sondern ein wurdiger, metaphysisch fundierter Disput. (shrink)

Working memory performance affects children’s learning. This study examined objective, subjective, and physiological cognitive load while children completed a spatial working memory complex span task. Frist, 80 Taiwanese 11-year-olds who participated in Experiment 1 confirmed the suitability of the materials. Then, 72 Taiwanese 11-year-olds were assigned to high and low complexity groups to participate in Experiment 2 to test the study hypothesis. Children had to recall at the end of a dual-task list and answer two questions regarding the difficulty and (...) mental effort involved in processing and storage. Their pupil diameters were recorded using an eye-tracker. Two-way mixed ANOVA found that the processing requirements and memory load reduced storage and aggravated the subjective CL of storage; the subjective CL of processing was higher under highly complex conditions. Stepwise regression analysis indicated that subjective CL of processing predicted memory performance in low CL conditions, and physiological CL of processing predicted it in high CL conditions. (shrink)