The disease brought about by the SARS-CoV-2, COVID-19 coronavirus has had an unprecedented global impact. Confinement to control the outbreak may have mental health consequences for the most vulnerable in the population, including adolescents. This study aims to describe and analyze the relationships between the stress variables, Emotional Intelligence and the intention to use cannabis in healthy adolescents, before and after the end of the COVID-19 pandemic containment stage. A comparative correlational study was carried out with validated self-completed questionnaires through (...) an online platform. The sample is made up of adolescents aged 13–17 from two different schools in Ponferrada. The analysis of correlation and differences between the groups indicate that confinement has had effects on the mental health of the adolescents, specifically on the emotional manifestations of stress. Furthermore, significant gender differences were found for stress values and Emotional Intelligence. However, no differences have been found for cannabis use intention. (shrink)

Riassunto: In questo contributo analizzeremo il criterio del danno, presente nella definizione generale di disturbo mentale del DSM. La questione ha rilevanza sia da un punto di vista filosofico, perché il danno è una componente normativa e valoriale, non oggettiva, sia da un punto di vista clinico, perché chi ha difeso il criterio del danno ha spesso sostenuto che in sua assenza avremmo troppi falsi positivi. Infine, ha importanza dal punto di vista socio-sanitario in relazione al rapporto tra la psichiatria (...) e la medicina non psichiatrica, nello specifico tra il DSM e l’ICD. Sosterremo che ci sono buone ragioni per non mantenere il danno come criterio necessario nella definizione generale del disturbo mentale. Dopo una breve introduzione, forniremo una panoramica storica sul ruolo del criterio del danno nelle varie edizioni del DSM. Successivamente si illustrerà la principale obiezione contro l’inclusione del criterio del danno nella definizione generale di disturbo mentale, ossia il problema dei falsi negativi, per poi presentare e discutere ulteriori ragioni – medico-pratiche e concettuali – che depongono a sfavore dell’attribuzione di un forte peso al criterio del danno. In sede conclusiva ribadiamo come la decisione presa dalla task force del DSM-5 di escludere il criterio del danno dalla definizione generale di disturbo mentale debba essere sostenuta. Parole chiave: Danno; Disabilità; Disagio; Disturbo mentale; DSM “Harm” as Criterion for the Definition of Mental Disease in DSM. Some Epistemological Reflections: In this paper, we analyse the harm requirement in the general definition of mental disorder in the Diagnostic and Statistical Manual for Mental Disorders. This issue has both philosophical and clinical relevance: on the one hand the harm requirement is a normative, value-laden, non-objective component in the definition of mental disorder; on the other hand, the harm requirement has often been defended on the grounds that it prevents an increase in false positives. The issue is also important in assessing the relationship between psychiatry and somatic medicine, more precisely, between the DSM and the International Classification of Diseases. We argue that there are good reasons not to maintain the harm requirement in the general definition of mental disorder. After a brief introduction, we overview the history of the harm requirement across the various editions of the DSM. Then, we examine the main objection to the inclusion of the harm requirement in the general definition of mental disorder, that is, the problem of false negatives, and also present several other points – both practical and conceptual – that help demonstrate why the harm requirement is inadequate as a definiens of mental disorder. To conclude, we stress that the decision of the DSM-5 task force not to regard the harm requirement as a necessary component of mental disorder should be endorsed. Keywords: Harm; Disability, Distress; Mental Disorder; DSM. (shrink)

Delia Cristina Balaban, Informationsvermittlung und öffentliche Meinungsbildung im rumänischen Fernsehen Editura Presa Universitarã, Cluj- Napoca, 2003.

In The Grammar of Society, first published in 2006, Cristina Bicchieri examines social norms, such as fairness, cooperation, and reciprocity, in an effort to understand their nature and dynamics, the expectations that they generate, and how they evolve and change. Drawing on several intellectual traditions and methods, including those of social psychology, experimental economics and evolutionary game theory, Bicchieri provides an integrated account of how social norms emerge, why and when we follow them, and the situations where we are (...) most likely to focus on relevant norms. Examining the existence and survival of inefficient norms, she demonstrates how norms evolve in ways that depend upon the psychological dispositions of the individual and how such dispositions may impair social efficiency. By contrast, she also shows how certain psychological propensities may naturally lead individuals to evolve fairness norms that closely resemble those we follow in most modern societies. (shrink)

In Norms in the Wild, distinguished philosopher Cristina Bicchieri argues that when it comes to human behavior, social scientists place too much stress on rational deliberation. In fact, she says, many choices occur without much deliberation at all. Two people passing in a corridor automatically negotiate their shared space; cars at an intersection obey traffic signals; we choose clothing based on our instincts for what is considered appropriate. Bicchieri's theory of social norms accounts for these automatic components of coordination, (...) where individuals react automatically to cues that focus their attention on what the norm is in that situation. Social norms thus act as rules for making choices in a social world where people expect others -- often unconsciously -- to follow the same rule. Some norms enable seamless social co-operation, while others are less beneficial to human flourishing.Bicchieri is famous for her interdisciplinary work on game theory and most recently her work on social norms, and Norms in the Wild represents her latest challenge to many of the fundamental assumptions of the social sciences. Bicchieri's work has broad implications not only for understanding human behavior, but for changing it for better outcomes. People have a strongly conditioned preference for following social norms, but that also means that manipulating their expectations can cause major behavioral changes. Bicchieri has been working recently with UNICEF and other NGO's to explore the applicability of her views to issues of human rights around the world. Is it possible to change social expectations around forced marriage, genital mutilations, and public health practices like vaccinations and sanitation? If so, how? What tools might we use? This short book explores how social norms work, and how changing them - changing preferences, beliefs, and especially social expectations - can potentially improve lives all around the world. It will appeal to an unusually broad range of readers including philosophers, psychologists and others in behavioral sciences, and anyone involved in public policy or at NGOs. (shrink)

We report the results of an experiment designed to determine the effects of psychological proximity—proxied by awareness of pain and friendship—on moral reasoning. Our study tests the hypotheses that a moral agent’s emphasis on justice decreases with proximity, while his/her emphasis on care increases. Our study further examines how personality, gender, and managerial status affect the importance of care and justice in moral reasoning. We find support for the main hypotheses. We also find that care should be split into two (...) components, one related to protection and the other to the preservation of relationships. Although gender does not affect moral reasoning directly, we find that it does so indirectly via personality, controlling for age, professional status, and professional background. We do not find a significant effect of managerial status on ethics of justice, but do find that holding a managerial position has a negative impact on ethics of care. Regarding personality, we detect significant positive effects of conscientiousness on ethics of justice and of neuroticism on ethics of care. (shrink)

The thesis of mental fragmentation has recently attracted increased attention as a way of explaining facts about mind and language. This volume provides an accessible introduction and essays on foundations and applications of fragmentation.

This book articulates a participatory conception of deliberative democracy that takes the democratic ideal of self-government seriously. It aims to improve citizens' democratic control and vindicate the value of citizens' participation against conceptions that threaten to undermine it. The book critically analyzes deep pluralist, epistocratic, and lottocratic conceptions of democracy. Their defenders propose various institutional ''shortcuts'' to help solve problems of democratic governance such as overcoming disagreements, citizens' political ignorance, or poor-quality deliberation. However, all these shortcut proposals require citizens to (...) blindly defer to actors over whose decisions they cannot exercise control. Implementing such proposals would therefore undermine democracy. Moreover, it seems naive to assume that a community can reach better outcomes 'faster' if it bypasses the beliefs and attitudes of its citizens. Unfortunately, there are no 'shortcuts' to make a community better than its members. The only road to better outcomes is the long, participatory road that is taken when citizens forge a collective will by changing one another's hearts and minds. However difficult the process of justifying political decisions to one another may be, skipping it cannot get us any closer to the democratic ideal. Starting from this conviction, the book defends a conception of democracy ''without shortcuts''. This conception sheds new light on long-standing debates about the proper scope of public reason, the role of religion in politics, and the democratic legitimacy of judicial review. It also proposes new ways to unleash the democratic potential of institutional innovations such as deliberative minipublics. (shrink)

En este artículo se investiga la índole y supuestos filosóficos básicos de dos perspectivas metafísicas y epistemológicas contrapuestas en torno a la célebre prueba ontológica de la existencia de Dios. Tales perspectivas son, por un lado, la esencia lista o realista fenomenológica, para la que, por admitir la objetividad y trascendencia de las llamadas "cualidades eidéticas necesarias", la prueba es válida y concluyente; por otro, la perspectiva existencialista o conceptualista, que, al negar tal objetividad y trascendencia, rechaza la validez de (...) la prueba. De este modo, la posición ante este problema metafísico fundamental puede constituir un criterio básico de diferenciación entre defensores y detractores del célebre argumento anselmiano. (shrink)

Nuestra intención en este artículo es exponer la concepción berkeleyana entorno al tan debatido problema de la filosofía de la modernidad que concierne a la relación, conocimiento y exterioridad. Éste constituye, en efecto, núcleo esencial de las filosofías de autores tan representativos de la época como Locke, Hume, Condillac y el propio Berkeley, entre otros. No obstante, la singularidad del planteamiento berkeleyano al respecto es tal, que bien merece por nuestra parte una reflexión antenta y por separado. Además, la influencia (...) que su aportación peculiar ejerció sobre determinados filósofos, como, por ejemplo, Condillac y Kant, y a través de ellos sobre buena parte de la filosofía posterior fue de tal índole, que sin el cabal conocimiento de ella no podría entenderse la relevancia y significación del idealismo gnoseológico en sus diferentes tipos y modalidades. En una primera sección, meramente introductoria, acometemos la exposición de la metafísica de Berkeley, destacándose sobre todo su teoría del inmaterialismo ; con ello se pretende subrayar en principio el carácter peculiar que forzosamente habrá de presentar su concepción de lo externo. El tratamiento de ésta constituye propiamente el contenido de la segunda sección, en la que, además de la identificación entre contenido sensible y realidad y de la apelación a la instancia divina como garante último de ésta, se destaca el papel preponderante que desempeña el sentido del tacto en el proceso de aprehensión de la exterioridad. (shrink)

Nuestra pretensión en este artículo es modesta: nos proponemos únicamente poner de relieve el doble sentido de los términos "idea" y "sensación" en la filosofía de los siglos XVII y XVIII. Como es sabido, ambos términos constituyen, respectivamente, el núcleo esencial del racionalismo y el empirismo. La idea para el primero y la sensación para el segundo se erigen ciertamente en piezas gnoseológicas clave sin las cuales ni uno ni otro podrían ser cabalmente comprendidos.

Providing people with information is considered an important first step in encouraging them to behave sustainably as it influences their consumption beliefs, attitudes and intentions. However, too much information can also complicate these processes and negatively affect behaviour. This is exacerbated when people have accepted the need to live a more sustainable lifestyle and attempt to enact its principles. Drawing on interview data with people committed to sustainability, we identify the contentious role of knowledge in further disrupting sustainable consumption ideals. (...) Here, knowledge is more than just information; it is familiarity and expertise or how information is acted upon. We find that more knowledge represents a source of dilemma, tension and paralysis. Our data reveal a dark side to people’s knowledge, leading to a ‘self-inflicted sustainable consumption paradox’ in their attempts to lead a sustainable consumption lifestyle. Implications for policy interventions are discussed. (shrink)

Many accounts of ethnic phenomena imply that processes such as stereotyping, essentialism, ethnocentrism, and intergroup hostility stem from a unitary adaptation for reasoning about groups. This is partly justified by the phenomena’s co-occurrence in correlational studies. Here we argue that these behaviors are better modeled as functionally independent adaptations that arose in response to different selection pressures throughout human evolution. As such, different mechanisms may be triggered by different group boundaries within a single society. We illustrate this functionalist framework using (...) ethnographic work from the Quechua-Aymara language boundary in the Peruvian Altiplano. We show that different group boundaries motivate different ethnic phenomena. For example, people have strong stereotypes about socioeconomic categories, which are not cooperative units, whereas they hold fewer stereotypes about communities, which are the primary focus of cooperative activity. We also show that, despite the cross-cultural importance of ethnolinguistic boundaries, the Quechua-Aymara linguistic distinction does not strongly motivate any of these intergroup processes. (shrink)

In this paper, we aim to enhance our understanding about the processing of implicit and explicit temporal chronological relations by investigating the roles of temporal connectives and verbal tenses, separately and in interaction. In particular, we investigate how two temporal connectives (ensuiteandpuis, both meaning ‘then’) and two verbal tenses expressing past time (the simple and compound past) act as processing instructions for chronological relations in French. Theoretical studies have suggested that the simple past encodes the instruction to relate events sequentially, (...) unlike the more flexible compound past, which does not. Using an online experiment with a self-paced reading task, we show that these temporal connectives facilitate the processing of chronological relations when they are expressed with both verbal tenses, and that no significant difference is found between the two verbal tenses, nor between the two connectives. By means of an offline experiment with an evaluation task, we find, contrary to previous studies, that comprehenders prefer chronological relations to be overtly marked rather than implicitly expressed, and prefer to use the connectivepuisin particular. Furthermore, comprehenders prefer it when these relations are expressed using the compound past, rather than the simple past. Instead of using thecontinuityhypothesis (Segal et al. 1991,Murray 1997) to explain the processing of temporal relations, we conclude that a more accurate explanation considers a cluster of factors including linguistic knowledge (connectives, tenses, grammatical and lexical aspect) and world knowledge. (shrink)

L.A. Paul calls “deep” the kind of essentialism according to which the essential properties of objects are determined independently of the context. Deep essentialism opposes “shallow essentialism”, of which David Lewis is said to be a prominent advocate. Paul argues that standard forms of deep essentialism face a range of issues (mainly based on an interpretation of Quinean skepticism) that shallow essentialism does not. However, Paul claims, shallow essentialism eliminates the very heart of what motivates essentialism, so it is better (...) to be deep than shallow. Accordingly, she proposes a very sharp novel account of essentialism, which, while attempting to preserve some of the advantages of shallow essentialism over the classical forms of deep essentialism, can be deemed to be deep. In this paper, I compare Paul’s proposal for a kind of deep essentialism with Lewis’s account, as it is presented by Paul. My aim is to show that the differences between the two approaches are not as significant as Paul takes them to be, and that Paul’s account can be taken to be deeper than Lewis’s only at the cost of sacrificing the very idea at the bottom of deep essentialism. This might be taken to suggest that, if Paul is correct in asserting that shallow essentialism is better equipped to address some skeptical challenges, but it is generally preferable to be deep than shallow, then Lewis’s account should be re-evaluated, since, as shallow as it can be, it might be deeper than it looks. (shrink)

The Internet has been identified in human enhancement scholarship as a powerful cognitive enhancement technology. It offers instant access to almost any type of information, along with the ability to share that information with others. The aim of this paper is to critically assess the enhancement potential of the Internet. We argue that unconditional access to information does not lead to cognitive enhancement. The Internet is not a simple, uniform technology, either in its composition, or in its use. We will (...) look into why the Internet as an informational resource currently fails to enhance cognition. We analyze some of the phenomena that emerge from vast, continual fluxes of information–information overload, misinformation and persuasive design—and show how they could negatively impact users’ cognition. Methods for mitigating these negative impacts are then advanced: individual empowerment, better collaborative systems for sorting and categorizing information, and the use of artificial intelligence assistants that could guide users through the informational space of today’s Internet. (shrink)

This paper argues that hypocritical blame renders blame inappropriate. Someone should not express her blame if she is guilty of the same thing for which she is blaming others, in the absence of an admission of fault. In failing to blame herself for the same violations of norms she condemns in another, the hypocrite evinces important moral faults, which undermine her right to blame. The hypocrite refuses or culpably fails to admit her own mistakes, while at the same time demands (...) that others admit theirs. The paper argues that this lack of reciprocity—expecting others to take morality seriously by apologizing for their faults, without one doing the same in return—is what makes hypocritical blame unfair. (shrink)

Using samples from three diverse populations, we test evolutionary hypotheses regarding how people reason about the inheritance of various traits. First, we provide a framework for differentiat-ing the outputs of mechanisms that evolved for reasoning about variation within and between biological taxa and culturally evolved ethnic categories from a broader set of beliefs and categories that are the outputs of structured learning mechanisms. Second, we describe the results of a modified “switched-at-birth” vignette study that we administered among children and adults (...) in Puno, Yasawa, and adults in the United States. This protocol permits us to study perceptions of prenatal and social transmission pathways for various traits and to differentiate the latter into vertical versus horizontal cultural influence. These lines of evidence suggest that people use all three mechanisms to reason about the distribution of traits in the population. Participants at all three sites develop expectations that morphological traits are under prenatal influence, and that belief traits are more culturally influenced. On the other hand, each population holds culturally specific beliefs about the degree of social influence on non-morphological traits and about the degree of vertical transmission—with only participants in the United States expecting parents to have much social influence over their children. We reinterpret people's differentiation of trait transmission pathways in light of humans' evolutionary history as a cultural species. (shrink)

We present five studies investigating the effects of approach and avoidance behaviours when individuals do not enact them but, instead, learn that others have performed them. In Experiment 1, when participants read that a fictitious character (model) had approached a previously unknown product, they ascribed to this model a liking for the object. In contrast, they ascribed to the model a disliking for the avoided product. In Experiment 2, this result emerged, with a smaller effect size, even when it was (...) clear that the behaviours followed specific instructions from a third party. The model had been a mere executor instead of behaving autonomously. Finally, in Experiments 3, 4, and 5, we showed, with direct and indirect measures of attitudes, that reading that the model had approached vs avoided products was sufficient to create preferences in the participant for the approached one, regardless of whether it was explained that the model was a mere executor. This research highlights the largely unexplored effects of vicarious approach/avoidance behaviours. Theoretical and practical implications and possible developments of this line of research are discussed. (shrink)

Many hypotheses have been advanced to explain the collective irrationality of COVID-19 vaccine hesitancy, such as partisanship and ideology, exposure to misinformation and conspiracy theories or the effectiveness of public messaging. This paper presents a complementary explanation to epistemic accounts of collective irrationality, focusing on the moral reasons underlying people’s decisions regarding vaccination. We argue that the moralization of COVID-19 risk mitigation measures contributed to the polarization of groups along moral values, which ultimately led to the emergence of collective irrational (...) behaviors. Collective irrationality arises from groups explicitly or implicitly endorsing values that ultimately harm both themselves and those around. The role of social media platforms in amplifying this polarization and contributing to the emergence of collective irrationality is also examined. Finally, potential strategies for addressing the moral sources of collective irrationality are discussed. (shrink)

Fibring is recognized as one of the main mechanisms in combining logics, with great signicance in the theory and applications of mathematical logic. However, an open challenge to bring is posed by the collapsing problem: even when no symbols are shared, certain combinations of logics simply collapse to one of them, indicating that bring imposes unwanted interconnections between the given logics. Modulated bring allows a ner control of the combination, solving the collapsing problem both at the semantic and deductive levels. (...) Main properties like soundness and completeness are shown to be preserved, comparison with bring is discussed, and some important classes of examples are analyzed with respect to the collapsing problem. (shrink)

Vivemos nos desdobramentos daquilo que Manuel Castells (2005) nomeou de Sociedade em Rede, em cujo cerne estão as Tecnologias de Informação (TIs). Ele indicou as características-chave do novo cenário que diagnosticou, a saber, são tecnologias que agem sobre a própria informação e que também introduziram a lógica das redes; que promovem a convergência tecnológica e, por conseguinte, um sistema altamente integrado de aparatos técnicos; e que acentuadamente penetram pelos diferentes processos e âmbitos sociais. De lá para cá testemunhamos grandes e (...) rápidos saltos tecnológicos bem como o adensamento das transformações na dinâmica econômico-política organizacional e institucional e na construção das vidas humanas e não-humanas no planeta. Essas mudanças alcançaram não apenas modos informais de aprendizagem, mas também a educação formal. O objetivo desse artigo é discutir aspectos atuais da plataformização educacional presentes na educação básica brasileira, tendo como referência o ensino de Filosofia no Ensino Médio. Para tanto será desenvolvida reflexão sobre a plataformização educacional, fenômeno que diz respeito ao modelo de negócios presente na atual fase do capitalismo e que utiliza as plataformas sustentadas pela IA e também a constante extração de dados de quem transita pelas infovias do ciberespaço; sobre o que nomeamos como Escola do Cansaço, em diálogo com o conceito de Sociedade do Cansaço desenvolvido por Byung Chul Han; e sobre algumas implicações decorrentes que já se fazem presentes na administração do trabalho docente, na realização do trabalho docente e nas relações de ensino-aprendizagem. (shrink)

The US healthcare industry emits an estimated 479 million tonnes of carbon dioxide each year; nearly 8% of the country’s total emissions. When assessed by sector, hospital care, clinical services, medical structures, and pharmaceuticals are the top emitters. For 15 years, research has been dedicated to the medical structures and equipment that contribute to carbon emissions. More recently, hospital care and clinical services have been examined. However, the carbon of pharmaceuticals is understudied. This article will focus on the carbon emissions (...) of pharmaceuticals since they are consistently calculated to be among the top contributors to healthcare carbon and assess the factors that contribute to pharmaceutical carbon emissions. Specifically, overprescription, pharmaceutical waste, antibiotic resistance, routine prescriptions, non-adherence, drug dependency, lifestyle prescriptions, and drugs given due to a lack of preventive healthcare will be identified. Prescribing practices have environmental ramifications. Carbon reduction, when focused on pharmaceuticals, can lead to cleaner, more sustainable healthcare. (shrink)

Through the analysis of an 18-month ethnography at an exotic dance club located in the Northeastern United States, I uncover how Latina exotic dancers manage their participation in exotic dance by deploying constructions of Latinidad as embodied cues. I focus on Playpen’s weekly event, “Latina Night,” to demonstrate how racialized, sexualized, and gendered constructs relative to Latinidad are produced and regulated in this exotic dance setting. Study participants draw on embodied markers to negotiate how their bodies are read. Those markers (...) include nationality-based appeals, time elapsed since migration, and the ability to express constructions of Latinidad through dance performance. I draw on intersectionality as a conceptual tool, filtered through a sensibility to Latina/o/x lives and experiences, to analyze the nuances of racialization as experienced by Latinas. This approach destabilizes the U.S. black–white racial binary and opens intersectionality to a more nuanced understanding of the production of Latinidad. By approaching racialization as an embodied phenomenon, I elucidate how bodily markers, beyond skin color, become imbued with racialized meaning and condition racialized erotic capital. No less important is how participants draw on racialized, gendered, and sexualized tropes to benefit racialized erotic capital. (shrink)

The carbon emissions of global health care activities make up 4–5% of total world emissions, placing it on par with the food sector. Carbon emissions are particularly relevant for health care because of climate change health hazards. Doctors and health care professionals must connect their health care delivery with carbon emissions and minimize resource use when possible as a part of their obligation to do no harm. Given that reducing carbon is a global ethical priority, the informed consent process in (...) health care delivery must change. I argue that the expanded role of bioethicists in this climate crisis is to promote and support “green informed consent:” the sharing of climate information with patients, offering options for lower-carbon health care, and accepting the patient’s right to decline treatments which are deemed too carbon intensive for their values. (shrink)

Lewis (1968) claims that his language of Counterpart Theory (CT) interprets modal discourse and he adverts to a translation scheme from the language of Quantifed Modal Logic (QML) to CT. However, everybody now agrees that his original translation scheme does not always work, since it does not always preserve the ‘intuitive’ meaning of the translated QML-formulas. Lewis discusses this problem with regard to the Necessitist Thesis, and I will extend his discourse to the analysis of the Converse Barcan Formula. Everyone (...) also agrees that there are CT-formulas that can express the QMLcontent that gets lost through the translation. The problem is how we arrive to them. In this paper, I propose new translation rules from QML to CT, based on a suggestion by Kaplan. However, I will claim that we cannot have ‘the’ translation scheme from QML to CT. The reason being that de re modal language is ambiguous. Accordingly, there are diferent sorts of QML, depending on how we resolve such ambiguity. Therefore, depending on what sort of QML we intend to translate into CT, we need to use the corresponding translation scheme. This suggests that all the translation problems might just disappear if we do what Lewis did not: begin with a fully worked out QML that tells us how to understand de re modal discourse. (shrink)

Cristina Lafont draws upon Hilary Putnam's work in particular to criticize the linguistic idealism and relativism of the German tradition, which she traces back to the assumption that meaning determines reference.

Neurosteroid 17 beta-estradiol (E2) is a steroid synthesized de novo in the nervous system that might influence neuronal activity and behavior. Nevertheless, the impact of E2 on the functioning of those neural systems in which it is slightly synthesized is less questioned. The vestibulo-ocular reflex (VOR) adaptation, may provide an ideal arena for investigating this issue. Indeed, E2 modulates cerebellar parallel fiber-Purkinje cell synaptic plasticity that underlies encoding of VOR adaptation. Moreover, aromatase expression in the cerebellum of adult rodents is (...) maintained at very low levels and localized to Purkinje cells. The significance of age-related maintenance of low levels of aromatase expression in the cerebellum on behavior, however, has yet to be explored. Our aim in this study was to determine whether E2 synthesis exerts an effective and persistent modulation of VOR adaptation in adult male rats. To answer this question, we investigated the acute effect of blocking E2 synthesis on gain increases and decreases in VOR adaptation using an oral dose (2.5 mg/kg) of the aromatase inhibitor Letrozole in peri-pubertal and post-pubertal male rats. We found that Letrozole acutely impaired gain increases and decreases in VOR adaptation without altering basal ocular-motor performance and that these effects were similar in peri-pubertal and post-pubertal rats. Thus, in adult male rats neurosteroid E2 effectively modulates VOR adaptation in both of the periods studied. These findings imply that the adult cerebellum uses E2 synthesis for modulating motor memory formation and suggest that low and extremely localized E2 production may play a role in adaptive phenomena. (shrink)