Background Currently there is increasing recognition of the need for research in developing countries where disease burden is high. Understanding the role of local factors is important for undertaking ethical research in developing countries. We explored factors relating to information and communication during the process of informed consent, and the approach that should be followed for gaining consent. The study was conducted prior to a family-based genetic study among people with podoconiosis (non-filarial elephantiasis) in southern Ethiopia. Methodology/Principal Findings We adapted (...) a method of rapid assessment validated in The Gambia. The methodology was entirely qualitative, involving focus-group discussions and in-depth interviews. Discussions were conducted with podoconiosis patients and non-patients in the community, fieldworkers, researchers, staff of the local non-governmental organisation (NGO) working on prevention and treatment of podoconiosis, and community leaders. We found that the extent of use of everyday language, the degree to which expectations of potential participants were addressed, and the techniques of presentation of information had considerable impact on comprehension of information provided about research. Approaching podoconiosis patients via locally trusted individuals and preceding individual consent with community sensitization were considered the optimal means of communication. Prevailing poverty among podoconiosis patients, the absence of alternative treatment facilities, and participants' trust in the local NGO were identified as potential barriers for obtaining genuine informed consent. Conclusions Researchers should evaluate the effectiveness of consent processes in providing appropriate information in a comprehensible manner and in supporting voluntary decision-making on a study-by-study basis. (shrink)

BackgroundThe consent process for a genetic study is challenging when the research is conducted in a group stigmatized because of beliefs that the disease is familial. Podoconiosis, also known as 'mossy foot', is an example of such a disease. It is a condition resulting in swelling of the lower legs among people exposed to red clay soil. It is a very stigmatizing problem in endemic areas of Ethiopia because of the widely held opinion that the disease runs in families and (...) is untreatable. The aim of this study was to explore the impact of social stigma on the process of obtaining consent for a study on the genetics of podoconiosis in Southern Ethiopia.MethodsWe adapted a rapid assessment tool validated in The Gambia. The methodology was qualitative involving focus-group discussions (n = 4) and in-depth interviews (n = 25) with community members, fieldworkers, researchers and staff of the Mossy Foot Treatment and Prevention Association (MFTPA) working on prevention and treatment of podoconiosis.ResultsWe found that patients were afraid of participation in a genetic study for fear the study might aggravate stigmatization by publicizing the familial nature of the disease. The MFTPA was also concerned that discussion about the familial nature of podoconiosis would disappoint patients and would threaten the trust they have in the organization. In addition, participants of the rapid assessment stressed that the genetic study should be approved at family level before prospective participants are approached for consent. Based on this feedback, we developed and implemented a consent process involving community consensus and education of fieldworkers, community members and health workers. In addition, we utilized the experience and established trust of the MFTPA to diminish the perceived risk.ConclusionThe study showed that the consent process developed based on issues highlighted in the rapid assessment facilitated recruitment of participants and increased their confidence that the genetic research would not fuel stigma. Therefore, investigators must seek to assess and address risks of research from prospective participants' perspectives. This involves understanding the issues in the society, the culture, community dialogues and developing a consent process that takes all these into consideration. (shrink)

In this article, the nature of Ethiopian modernity will be explored through the usage of concepts like coloniality, entangled modernities and uneven histories that are borrowed from decolonial and postcolonial perspectives. Through such an analysis, the Ethiopian discourse on modernity will be presented as a conception of social progress that developed in a dialectical relationship with liberal, Marxist, indigenous and religiously inspired conceptions of modernity. It will be argued that resisting the attempts to romanticize the past as a foundation of (...) cultural revival and also the attempt to confine the discussion of Ethiopian modernity to the introduction of western modernization, Ethiopian modernity should be alternatively conceptualized as a discourse that is co-constituted in an active confrontation with alternative visions of progress. The article argues that the diagnosis of the multiple and interconnected discourses that shaped the Ethiopian discourse on modernity serves as a foundation of an Ethiopian critical theory. Such a theory creatively synthesizes cultural values, hosts an inclusive political culture that furnishes the culture of public criticism and introduces a world of knowledge production that overcomes Eurocentrism. (shrink)

In this article after identifying four major trends in the discourse on Ethiopian philosophy, it will be argued that there is a need to introduce a mature conception of Ethiopian philosophy that can both diagnose existential predicaments and also has the ability of introducing an emancipatory dimension. At the heart of this article is the claim that there are four major trends in Ethiopian philosophy which is a discourse that is still looking for an identity and that these trends are (...) characterized by hermeneutics, intercultural philosophy, critical theory and indigenous Ethiopian philosophy. After identifying the limitations of the four trends in Ethiopian philosophy, the article will point towards the development of a new discourse in Ethiopian philosophy that has the power of pointing towards the emergence of a new discourse that is able to diagnose existing realties and also can engage in a dialogue with other philosophical traditions. (shrink)