The feasibility of reversing human aging within a matter of decades has traditionally been dismissed by all professional biogerontologists, on the grounds that not only is aging still poorly understood, but also many of those aspects that we do understand are not reversible by any current or foreseeable therapeutic regimen. This broad consensus has recently been challenged by the publication, by five respected experimentalists in diverse subfields of biogerontology together with three of the present authors, of an article (Ann NY (...) Acad Sci 959, 452–462) whose conclusion was that all the key components of mammalian aging are indeed amenable to substantial reversal (not merely retardation) in mice, with technology that has a reasonable prospect of being developed within about a decade. Translation of that panel of interventions to humans who are already alive, within a few decades thereafter, was deemed potentially feasible (though it was not claimed to be likely). If the prospect of controlling human aging within the foreseeable future cannot be categorically rejected, then it becomes a matter of personal significance to most people presently alive. Consequently, we suggest that serious public debate on this subject is now warranted, and we survey here several of the biological, social and political issues relating to it. BioEssays 24:667–676, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

The feasibility of reversing human aging within a matter of decades has traditionally been dismissed by all professional biogerontologists, on the grounds that not only is aging still poorly understood, but also many of those aspects that we do understand are not reversible by any current or foreseeable therapeutic regimen. This broad consensus has recently been challenged by the publication, by five respected experimentalists in diverse subfields of biogerontology together with three of the present authors, of an article (Ann NY (...) Acad Sci 959, 452–462) whose conclusion was that all the key components of mammalian aging are indeed amenable to substantial reversal (not merely retardation) in mice, with technology that has a reasonable prospect of being developed within about a decade. Translation of that panel of interventions to humans who are already alive, within a few decades thereafter, was deemed potentially feasible (though it was not claimed to be likely). If the prospect of controlling human aging within the foreseeable future cannot be categorically rejected, then it becomes a matter of personal significance to most people presently alive. Consequently, we suggest that serious public debate on this subject is now warranted, and we survey here several of the biological, social and political issues relating to it. BioEssays 24:667–676, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

Arguing for a new direction in postmodern theological thinking, away from the liberalism and nihilism of those who name themselves postmodern theologians, the ...

The sketch shows relations of the late poetry of Jarosław Marek Rymkiewicz with a music and the topic of death. Poet articulates a belief that transverbal property of music deepens and extends the ability of poetry to express the thanatological matters. Rymkiewicz describes life as a constant tending to death. This tending is shown in his poems as a danse moriendi, dance in a rhythm of waltz or ländler. Through the music it connects with the cosmic rhythm of nature, the (...) wheel of every existence. Rymkiewicz convinces also that lyrical poetry related with music can defy nothingness. Thanks to oniristic poetic creation poems-songs and poems-ariettes preserve, as in a fairy tale, the continuity of life. (shrink)

Based on Michel Foucault's 1978 and 1979 lectures at the Collège de France on governmental rationalities and his 1977 interview regarding his work on imprisonment, this volume is the long-awaited sequel to Power/Knowledge.

This two-part volume collects the complete fragments and most important testimonies for the leading presocratic philosophers. The Greek and Latin texts are translated on facing pages and accompanied by a brief commentary for each philosopher.

This essay argues for a two-part thesis concerning the deflationist theories of truth and reference. First, I identify two points of contrast between the deflationist theories and their traditional inflationary opponents: (1) they each employ different orders of explanation for the variety of semantic phenomena, and (2) the inflationist is typically taken to be beholden to a reductive explanation of reference, whereas the deflationist is doubtful of this project. Secondly, I argue that these two points of contrast need not come (...) together to exhaust the space of possible views. There is room for a plausible middle ground: a moderate version of inflationism. My moderate inflationism will reject the deflationist's order of explanation, so it counts as genuinely inflationary. However, it also rejects the reductionist ambitions of the earlier inflationists, so it isn’t an apt target for deflationary scepticism. (shrink)

Most phobias are focussed on a small number of fear-inducing stimuli (e.g., snakes, spiders). A review of the evidence supporting biological and cognitive explanations of this uneven distribution of phobias suggests that the readiness with which such stimuli become associated with aversive outcomes arises from biases in the processing of information about threatening stimuli rather than from phylogenetically based associative predispositions or “biological preparedness.” This cognitive bias, consisting of a heightened expectation of aversive outcomes following fear-relevant stimuli, generates and maintains (...) robust learned associations between them. Some of the features of such stimuli which determine this expectancy bias are estimates of how dangerous they are, the semiotic similarity between them and their aversive outcomes, and the degree of prior fear they elicit. Ontogenetic and cultural factors influence these features of fear-relevant stimuli and are hence important in determining expectancy bias. The available evidence does not exclude the possibility that both expectancy biases and specific evolved predispositions coexist, but the former can explain a number of important findings that the latter cannot. (shrink)

Examines the influence of the physical and biological sciences on society, ethics, and philosophy during the twentieth century.

Philosophers of science are increasingly arguing for the importance of doing scientifically- and socially-engaged work, suggesting that we need to reduce barriers to extra-disciplinary engagement and broaden our impact. Yet, we currently lack empirical data to inform these discussions, leaving a number of important questions unanswered. How common is it for philosophers of science to engage other communities, and in what ways are they engaging? What barriers are most prevalent when it comes to broadly disseminating one’s work or collaborating with (...) others? To what extent do philosophers of science actually value an engaged approach? Our project addresses this gap in our collective knowledge by providing empirical data regarding the state of philosophy of science today. We report the results of a survey of 299 philosophers of science about their attitudes towards and experiences with engaging those outside the discipline. Our data suggest that a significant majority of philosophers of science think it is important for non-philosophers to read and make use of their work; most are engaging with communities outside the discipline; and many think philosophy of science, as a discipline, has an obligation to ensure it has a broader impact. Interestingly, however, many of these same philosophers believe engaged work is generally undervalued in the discipline. We think these findings call for cautious optimism on the part of those who value engaged work—while there seems to be more interest in engaging other communities than many assume, significant barriers still remain. (shrink)

This brief paper builds on my recently published work on financial capitalism. My objective here is (a) to sketch an account of the primary social features of post-1970s financialised capitalism, (b) to identify select dynamics or mechanisms that have resulted in these features, (c) to outline a programme of research to enhance our explanatory understanding of the ‘fractured society’ via the sociological concepts of structure, culture and agency, and (d) to broach, characterize and assess likely prospects and triggers for the (...) accomplishment of a credible, defensible post-capitalist societal formation. (shrink)

This book provides a sustained and penetrating critique of a wide range of views in modern cognitive science and philosophy of the mind, from Turing's famous test for intelligence in machines to recent work in computational linguistic theory. While discussing many of the key arguments and topics, the authors also develop a distinctive analytic approach. Drawing on the methods of conceptual analysis first elaborated by Wittgenstein and Ryle, the authors seek to show that these methods still have a great deal (...) to offer in the field of the cognitive theory and the philosophy of mind, providing a powerful alternative to many of the positions put forward in the contemporary literature. Amoung the many issues discussed in the book are the following: the Cartesian roots of modern conceptions of mind; Searle's 'Chinese Room' thought experiment; Fodor's 'language of thought' hypothesis; the place of 'folk psychology' in cognitivist thought; and the question of whether any machine may be said to 'think' or 'understand' in the ordinary senses of these words. Wide ranging, up-to-date and forcefully argued, this book represents a major intervention in contemporary debates about the status of cognitive science an the nature of mind. It will be of particular interest to students and scholars in philosophy, psychology, linguistics and computing sciences. (shrink)

Even though disquotationalism is not correct as it is usually formulated, a deep insight lies behind it. Specifically, it can be argued that, modulo implicit commitment to reflection principles, all there is to the notion of truth is given by a simple, natural collection of truth-biconditionals.

Teleosemantics seeks to explain meaning and other intentional phenomena in terms of their function in the life of the species. This volume of new essays from an impressive line-up of well-known contributors offers a valuable summary of the current state of the teleosemantics debate.

A theory of truth is language-transcendent if it ascribes truth conditions to truth-bearers that are not expressible in our natural language; a theory is language-immanent if it is not language-transcendent. In this paper, I argue for the following theses. Whether the correct theory of truth is language-transcendent or language-immanent will have significant consequences for general philosophy. Prima facie, a language-transcendent theory is preferable. However, language-transcendent theories tend to require substantive metaphysical commitments concerning truth. Deflationist theories are particularly interesting in this (...) context. I argue that, if deflationism is to remain consistent with its motivations, then it must opt for a language-immanent conception of truth. (shrink)

Altered state theories of hypnosis posit that a qualitatively distinct state of mental processing, which emerges in those with high hypnotic susceptibility following a hypnotic induction, enables the generation of anomalous experiences in response to specific hypnotic suggestions. If so then such a state should be observable as a discrete pattern of changes to functional connectivity (shared information) between brain regions following a hypnotic induction in high but not low hypnotically susceptible participants. Twenty-eight channel EEG was recorded from 12 high (...) susceptible (highs) and 11 low susceptible (lows) participants with their eyes closed prior to and following a standard hypnotic induction. The EEG was used to provide a measure of functional connectivity using both coherence (COH) and the imaginary component of coherence (iCOH), which is insensitive to the effects of volume conduction. COH and iCOH were calculated between all electrode pairs for the frequency bands: delta (0.1–3.9Hz), theta (4–7.9Hz) alpha (8–12.9Hz), beta1 (13–19.9Hz), beta2 (20–29.9Hz) and gamma (30–45Hz). The results showed that there was an increase in theta iCOH from the pre-hypnosis to hypnosis condition in highs but not lows with a large proportion of significant links being focused on a central-parietal hub. There was also a decrease in beta1 iCOH from the pre-hypnosis to hypnosis condition with a focus on a fronto-central and an occipital hub that was greater in high compared to low susceptibles. There were no significant differences for COH or for spectral band amplitude in any frequency band. The results are interpreted as indicating that the hypnotic induction elicited a qualitative change in the organization of specific control systems within the brain for high as compared to low susceptible participants. This change in the functional organization of neural networks is a plausible indicator of the much theorized “hypnotic-state”. (shrink)

This paper attempts to explain what a protest is by using the resources of speech-act theory. First, we distinguish the object, redress, and means of a protest. This provided a way to think of atomic acts of protest as having dual communicative aspects, viz., a negative evaluation of the object and a connected prescription of redress. Second, we use Austin’s notion of a felicity condition to further characterize the dual communicative aspects of protest. This allows us to distinguish protest from (...) some other speech acts which also involve a negative evaluation of some object and a connected prescription of redress. Finally, we turn to Kukla and Lance’s idea of a normative functionalist analysis of speech acts to advance the view that protests are a complex speech act constituted by dual input normative statuses and dual output normative statuses. (shrink)

I argue that the Hume of the Treatise maintains an account of knowledge according to which (i) every instance of knowledge must be an immediately present perception (i.e., an impression or an idea); (ii) an object of this perception must be a token of a knowable relation; (iii) this token knowable relation must have parts of the instance of knowledge as relata (i.e., the same perception that has it as an object); and any perception that satisfies (i)-(iii) is an instance (...) of knowledge. I then apply this account to the case of sense perception. I argue that Hume holds that relations of impressions can be intuited, are knowable, and are necessary. For Hume, these relations constitute sensory knowledge. While Hume is rightly labeled an empiricist for many reasons, a close inspection of his account of knowledge reveals yet another way in which he deserves the label. (shrink)

In the year 1308, Cardinal Giacomo Colonna was a tremendously busy man. He had returned to Rome only a few years earlier in the aftermath of a devastating papal war waged against his family by Boniface VIII. The papal court had been absent from the city for years, leaving an administrative void in Rome as it established itself first in Poitiers, then in Avignon from 1308 under the leadership of the Gascon pope Clement V. In 1306 Giacomo was fully reinstated (...) to the cardinalate, and set about rebuilding his family's fortunes and reputation, as well as a number of the city's churches. He commissioned a new mosaic facade for the basilica of Santa Maria Maggiore, and in 1308 he oversaw repairs... (shrink)

Context: For Graham Barnes, the starting point of his research was the observation that most psychotherapists are trained in a theory-centered style of practice, neglecting epistemological and ….

There are some necessary conditions on causal relations that seem to be so trivial that they do not merit further inquiry. Many philosophers assume that the requirement that there could be no temporal gaps between causes and their effects is such a condition. Bertrand Russell disagrees. In this paper, an in-depth discussion of Russell’s argument against this necessary condition is the centerpiece of an analysis of what is at stake when one accepts or denies that there can be temporal gaps (...) between causes and effects. It is argued that whether one accepts or denies this condition, one is implicated in taking on substantial and wide-ranging philosophical positions. Therefore, it is not a trivial necessary condition of causal relations and it merits further inquiry. (shrink)

This introductory article outlines how this special issue contributes to existing scholarship that calls for a rethinking and re-evaluation of common assumptions about early modern philosophy. One way of challenging existing narratives is by questioning what role systems or systematicity play during this period. Another way of rethinking early modern philosophy is by considering assumptions about the role of philosophy itself and how philosophy can effect change in those who form philosophical beliefs or engage in philosophical argumentation. A further way (...) of advancing early modern scholarship is by examining the tight links between early modern views on metaphysics and epistemology, on the one hand, and moral, social, and political philosophy, on the other hand. Moreover, there are ongoing debates whether and how the traditional distinction between rationalism and empiricism, which has been questioned for several reasons, should be replaced. It has been proposed to replace it with a distinction between experimental and speculative philosophy, but this distinction cannot easily accommodate early modern debates concerning moral, social, and political philosophy. In addition to highlighting several ways how early modern philosophy has and can be rethought, we summarize how the papers in this special issue contribute to these ongoing efforts. (shrink)

This paper critically examines several game theoretic interpretations of Hobbes' state of nature, including Prisoner's Dilemma and Assurance Game, and argues instead that the best matrix is that of a combination of the two, an Assurance Dilemma. This move is motivated by the fact that Hobbes explicitly notes two distinct personality types, with different preference structures, in the state of nature: dominators and moderates. The former play as if in a Prisoner's Dilemma, the latter play as if in an Assurance (...) Game. But when meeting one another, the Assurance Dilemma represents their differing strategies, and can explain various other features of Hobbes' state of nature, as well as a key informational role played the Sovereign. (shrink)

Understanding and managing trust is a critical competency for organisations that take their ethical values seriously. Organisations need to know how trust is won, developed and sustained, and also what to do when that trust is threatened or has broken down. This Report helps organisations understand what trust is and how it is established at the interpersonal and organisational level. It outlines strategies for building and sustaining a resilient reputation for organisational trustworthiness and, through the use of case studies, illustrates (...) good and poor practice in repairing internal trust after an organisational failure. (shrink)

The question—what is a political constitution?—might seem, at first blush, fairly innocuous. At one level, the idea of a political constitution seems fairly well settled, at least insofar as most political constitutionalists subscribe to a similar set of commitments, arguments and assumptions. At a second, more reflective level, however, there remains some doubt whether a political constitution purports to be a descriptive or normative account of a real world constitution, such as Britain’s. By exploring the idea of a political constitution (...) as differently articulated by J.A.G. Griffith, Adam Tomkins and Richard Bellamy, this essay explores why the normativity of a political constitution may be indistinct and ill-defined, and how compelling reasons for this indistinctness and ill-definition are to be found in the very idea of a political constitution itself. A political constitution is here conceived as a ‘model’ which supplies an explanatory framework within which to make sense of our constitutional self-understandings. The discipline of thinking in terms of a model opens up a critical space wherein there need not be some stark, all-encompassing choice between constitutional models, which, in turn, allows for more subtle understandings of Britain’s constitution as neither exclusively ‘political’ nor ‘legal’. (shrink)

This _Companion_ provides an authoritative survey of the whole range of Kant’s work, giving readers an idea of its immense scope, its extraordinary achievement, and its continuing ability to generate philosophical interest. Written by an international cast of scholars Covers all the major works of the critical philosophy, as well as the pre-critical works Subjects covered range from mathematics and philosophy of science, through epistemology and metaphysics, to moral and political philosophy.

Hylomorphism is the Aristotelian theory according to which substances are composites of matter and form. If my house is a substance, then its matter would be a collection of bricks and timbers and its form something like a structure that unites those bricks and timbers into a single substance. Contemporary hylomorphists are divided on how to understand forms best, but a prominent group of theorists argue that forms are emergent powers. According to such views, when material components are arranged appropriately, (...) a novel substance emerges with the power to impose unity on its components through time. I argue that these accounts of form fall prey to a bootstrapping problem, and so, suffer from issues of redundancy, given plausible assumptions about inherence. In their place, I suggest an ontologically minimalist conception of forms as collective manifestations of the powers of matter. (shrink)

This monograph reappraises the role of Bertrand Russell's philosophical works in establishing the analytical tradition in philosophy. It's main aims are to: * improve our understanding of the history of analytical philosophy * engage in the important disputes surrounding the interpretation of Russell's philosophy * make a contribution to central issues in current analytical philosophy. Drawing extensively from Russell's less well known and unpublished works, this book is a welcome addition to the literature and will undoubtedly find a place on (...) the bookshelves of philosophers around the world. (shrink)