Type 2 diabetes mellitus is associated with cognitive impairment in many domains. There are several pieces of evidence that changes in neuronal neuropathies and metabolism have been observed in T2DM. Structural and functional MRI shows that abnormal connections and synchronization occur in T2DM brain circuits and related networks. Neuroplasticity and energy metabolism appear to be principal effector systems, which may be related to amyloid beta deposition, although there is no unified explanation that includes the complex etiology of T2DM with cognitive (...) impairment. Herein, we assume that cognitive impairment in diabetes may lead to abnormalities in neuroplasticity and energy metabolism in the brain, and those reflected to MRI structural connectivity and functional connectivity, respectively. (shrink)

We observe that Putnam’s model-theoretic argument against determinacy of the concept of second-order quantification or that of the set is harmless to the nominalist. It serves as a good motivation for the nominalist philosophy of mathematics. But in the end it can lead to a serious challenge to the nominalist account of mathematical objectivity if some minimal assumptions about the relation between mathematical objectivity and logical objectivity are made. We consider three strategies the nominalist might take to meet this challenge, (...) and we argue that all these strategies are untenable. (shrink)

v. 1. Li ze xue -- v. 2. Yu zhou lun xin li xue -- v. 3 Xing shang xue.