Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease, primarily leading to the degeneration of motor neurons. The traditional focus on motor neuron‐centric mechanisms has recently shifted towards understanding the contribution of non‐neuronal cells, such as microglia, in ALS pathophysiology. Advances in induced pluripotent stem cell (iPSC) technology have enabled the generation of iPSC‐derived microglia monocultures and co‐cultures to investigate their role in ALS pathogenesis. Here, we briefly review the insights gained from these studies into the role of microglia in ALS. (...) While iPSC‐derived microglia monocultures have revealed intrinsic cellular dysfunction due to ALS‐associated mutations, microglia‐motor neuron co‐culture studies have demonstrated neurotoxic effects of mutant microglia on motor neurons. Based on these findings, we briefly discuss currently unresolved questions and how they could be addressed in future studies. iPSC models hold promise for uncovering disease‐relevant pathways in ALS and identifying potential therapeutic targets. (shrink)

Talbot Brewer offers a new approach to ethical theory, founded on a far-reaching reconsideration of the nature and sources of human agency.

One On addressing understanding People know what they do; they frequently know why they do what they do; but what they don't know is what what they do does. ...

Predictable polarization is everywhere: we can often predict how people’s opinions, including our own, will shift over time. Extant theories either neglect the fact that we can predict our own polarization, or explain it through irrational mechanisms. They needn’t. Empirical studies suggest that polarization is predictable when evidence is ambiguous, that is, when the rational response is not obvious. I show how Bayesians should model such ambiguity and then prove that—assuming rational updates are those which obey the value of evidence—ambiguity (...) is necessary and sufficient for the rationality of predictable polarization. The main theoretical result is that there can be a series of such updates, each of which is individually expected to make you more accurate, but which together will predictably polarize you. Polarization results from asymmetric increases in accuracy. This mechanism is not only theoretically possible, but empirically plausible. I argue that cognitive search—searching a cognitively accessible space for a particular item—often yields asymmetrically ambiguous evidence, I present an experiment supporting its polarizing effects, and I use simulations to show how it can explain two of the core causes of polarization: confirmation bias and the group polarization effect. (shrink)

An understanding of the ethical implications of their work is now essential for all scientists. This accessible textbook clearly explains bioethical theories and their philosophical foundations to science students, enabling them to confidently take part in the key ethical debates of biotechnology. Over 200 activities introduce topics for personal reflection and discussion points encourage students to think for themselves and build their own arguments. Highlighting the potential pitfalls for those new to bioethics, each chapter features boxes providing factual information and (...) outlining the philosophical background. Accompanying online podcasts by the author (two of whose podcasts on iTunesU have attracted over 3 million downloads) explain points that might be difficult for beginners. Detailed case studies provide an insight into real-life examples of bioethical problems. Within-chapter essay questions and quizzes, along with end-of-chapter review questions, allow students to check their understanding and encourage broader thinking about the topics discussed. (shrink)

A definition of emotion common to the affective sciences is an urgent desideratum. Lack of such a definition is a constant source of numerous misunderstandings and a series of mostly fruitless debates. There is little hope that there ever will be agreement on a common definition of emotion, given the sacred traditions of the disciplines involved and the egos of the scholars working in these disciplines. Our aim here is more modest. We propose a list of elements for a working (...) definition of emotion and discuss the justification for the inclusion of elements from our respective perspectives (philosophy and psychology). This working partial definition may at least serve as a litmus test to examine theories of emotion, old and new, across disciplinary boundaries. (shrink)

The potential for financial conflicts of interest (COIs) to damage the credibility of scientific research has become a significant social concern, especially in the wake of high-profile incidents involving the pharmaceutical, tobacco, fossil-fuel, and chemical industries. Scientists and policy makers have debated whether the presence of financial COIs should count as a reason for treating research with suspicion or whether research should instead be evaluated solely based on its scientific quality. This paper examines a recent proposal to develop criteria for (...) evaluating the credibility of research without considering its source of funding. It concludes that proposals of this sort are likely to be either ineffective or impractical in many cases. Nevertheless, this does not imply that all research funded by those with an interest in the outcome must be placed under a cloud of suspicion; there are conditions under which research is at much more serious risk of being corrupted than in other cases, and attention to these conditions can guide productive responses to financial COIs. (shrink)

This book explores the way in which, working within the investigative tradition associated with the Royal Society, the philosopher John Locke (1632-1704) used ...

We argue that explainable artificial intelligence (XAI), specifically reason-giving XAI, often constitutes the most suitable way of ensuring that someone can properly be held responsible for decisions that are based on the outputs of artificial intelligent (AI) systems. We first show that, to close moral responsibility gaps (Matthias 2004), often a human in the loop is needed who is directly responsible for particular AI-supported decisions. Second, we appeal to the epistemic condition on moral responsibility to argue that, in order to (...) be responsible for her decision, the human in the loop has to have an explanation available of the system’s recommendation. Reason explanations are especially well-suited to this end and we examine whether – and how – it might be possible to make such explanations fit with AI systems. We support our claims by focusing on a case of disagreement between human in the loop and AI system. (shrink)

Boyer & Petersen lay out a compelling theory for folk-economic beliefs, focusing on beliefs about markets. However, societies also allocate resources through mechanisms involving power and group decision-making, through the political economy. We encourage future work to keep folkpoliticaleconomic beliefs in mind, and sketch an example involving pollution and climate change mitigation policy.

De Dreu and Gross's distinction between attack and defense is complicated in real-world conflicts because competing leaders construe their position as one of defense, and power imbalances place status quo challengers in a defensive position. Their account of defense as vigilant avoidance is incomplete because it avoids a reference to anger which transforms anxious avoidance into collective and unified action.

Husserl seems to have devoted roughly equal amounts of energy and pages to the description of perception, judgement, and imagination. By “description,” he meant the analysis of the traits and components of mental states or acts and their objects. As his views changed over the years about the nature of intentionality and philosophy, the descriptive psychology of the Logical Investigations (1900/01) gave way to descriptive programmes in which the objects of perception and of judgement were conceived of in terms of (...) a new, analytic framework; in particular Husserl lost interest in describing the things and processes in the real world that are the objects of perception and judgement and so too in describing their relations to these acts. His new analytic framework, particularly as it applies to perception, has been thoroughly expounded and discussed in the literature. My aim here is to expound Husserl's first descriptions of perception within the framework of the Investigations and to incorporate as far as possible his later descriptive results to the extent that these are separable from his later turn to idealism. (shrink)

There are many things—call them ‘experts’—that you should defer to in forming your opinions. The trouble is, many experts are modest: they’re less than certain that they are worthy of deference. When this happens, the standard theories of deference break down: the most popular (“Reflection”-style) principles collapse to inconsistency, while their most popular (“New-Reflection”-style) variants allow you to defer to someone while regarding them as an anti-expert. We propose a middle way: deferring to someone involves preferring to make any decision (...) using their opinions instead of your own. In a slogan, deferring opinions is deferring decisions. Generalizing the proposal of Dorst (2020a), we first formulate a new principle that shows exactly how your opinions must relate to an expert’s for this to be so. We then build off the results of Levinstein (2019) and Campbell-Moore (2020) to show that this principle is also equivalent to the constraint that you must always expect the expert’s estimates to be more accurate than your own. Finally, we characterize the conditions an expert’s opinions must meet to be worthy of deference in this sense, showing how they sit naturally between the too-strong constraints of Reflection and the too-weak constraints of New Reflection. (shrink)

Phenomenal Conservatism (the view that an appearance that p gives one prima facie justification for believing that p) is a promising, and popular, internalist theory of epistemic justification. Despite its popularity, it faces numerous objections and challenges. For instance, epistemologists have argued that Phenomenal Conservatism is incompatible with Bayesianism, is afflicted by bootstrapping and cognitive penetration problems, does not guarantee that epistemic justification is a stable property, does not provide an account of defeat, and is not a complete theory of (...) epistemic justification. This book shows that Phenomenal Conservatism is actually immune to some of these problems, though not all of them. Accordingly, it explores the prospects of integrating Phenomenal Conservatism with Explanationism (the view that epistemic justification is a matter of explanatory relations between one’s evidence and propositions supported by that evidence). The resulting theory, Phenomenal Explanationism, has advantages over Phenomenal Conservatism and Explanationism taken on their own. Phenomenal Explanationism is a highly unified, comprehensive internalist theory of epistemic justification that delivers on the promises of Phenomenal Conservatism while avoiding its pitfalls. (shrink)

An important and engaging book on a key argument in contemporary debates about free will and moral responsibility.

In 2022, students at North American universities with third-dose COVID-19 vaccine mandates risk disenrolment if unvaccinated. To assess the appropriateness of booster mandates in this age group, we combine empirical risk-benefit assessment and ethical analysis. To prevent one COVID-19 hospitalisation over a 6-month period, we estimate that 31 207–42 836 young adults aged 18–29 years must receive a third mRNA vaccine. Booster mandates in young adults are expected to cause a net harm: per COVID-19 hospitalisation prevented, we anticipate at least (...) 18.5 serious adverse events from mRNA vaccines, including 1.5–4.6 booster-associated myopericarditis cases in males (typically requiring hospitalisation). We also anticipate 1430–4626 cases of grade ≥3 reactogenicity interfering with daily activities (although typically not requiring hospitalisation). University booster mandates are unethical because they: (1) are not based on an updated (Omicron era) stratified risk-benefit assessment for this age group; (2) may result in a net harm to healthy young adults; (3) are not proportionate: expected harms are not outweighed by public health benefits given modest and transient effectiveness of vaccines against transmission; (4) violate the reciprocity principle because serious vaccine-related harms are not reliably compensated due to gaps in vaccine injury schemes; and (5) may result in wider social harms. We consider counterarguments including efforts to increase safety on campus but find these are fraught with limitations and little scientific support. Finally, we discuss the policy relevance of our analysis for primary series COVID-19 vaccine mandates. (shrink)

Introduction -- Organization, society and politics -- An Aristotelian perspective -- The politics -- The public good -- The rhetoric -- Talk and texts -- The Nichomachean ethics -- Decision making and ethics -- The Poetics -- Bolshevism to ballet in three steps -- What is "public interest"?: a case study -- Where do we go from here?

Perhaps the most fundamental and distinctive idea of Kantian moral psychology is that no behavior can count as action unless it is performed on a subjective practical principle, or a maxim of action. The maxim is supposed to provide the target of moral assessment of all actions, whether this assessment is prospective or retrospective. The presence of a maxim is also supposed to illuminate how it is that agents are active in, hence responsible for, the peculiar species of events we (...) call actions. To put the point roughly, agents are the sources of their actions in that they have in some sense affirmed or endorsed the maxims of these actions. (shrink)

It is not clear whether to assess Robert Audi’s Moral Knowledge and Ethical Character as a collection of essays or a unified piece of theorizing. Seven of the book’s twelve essays have been published before, and at first blush they appear connected by little more than a common focus on ethics. These essays are framed, however, by an introduction and conclusion characterizing the book as the elaboration of a single, large-scale ethical theory. Perhaps a comprehensive theory can be disentangled from (...) these essays, but its contours and merits would be far clearer if Audi had presented it systematically, drawing selectively from previous essays rather than reproducing them wholesale. (shrink)

This paper presents the results of two corpus studies investigating the discourse surrounding conspiracy theories and genuine theories. The results of these studies show that conspiracy theories lack the epistemic and scientific standing characteristic of theories more generally. Instead, our findings indicate that conspiracy theories are spread in a manner that resembles the dissemination of rumors and falsehoods. Based on these empirical results, we argue that it is time for both re-engineering conspiracy theory and for relabeling "conspiracy theory". We propose (...) relabelling conspiracy theories as either "conspiracy stories" or "conspiracy narratives" to more accurately convey their true nature. (shrink)

ABSTRACTAndrew Bacon, Matti Eklund, and Patrick Greenough have individually proposed objections to the project in my book, Replacing Truth. Briefly, the book outlines a conceptual engineering project – our defective concept of truth is replaced for certain purposes with a team of concepts that can do some of the jobs we thought truth could do. Here, I respond to their objections and develop the views expressed in Replacing Truth in various ways.

Quantum mechanics describes a universe with physical properties that run completely contrary to everyday experience and intuition. These strange properties cause some people to seek equally strange philosophical theories to explain them. Talbot attempts to link the physical theories with some non-physical experimental results. The latter are, if true, disturbing and fascinating. Among the subjects explored are poltergeists, the possibility of instantaneous communication across great distances, and the nature of the mind and consciousness. This is an interesting combination of (...) physics, metaphysics, and parapsychology. Harold D. Shane, Mathematics Dept., Baruch Coll., CUNY. (shrink)

Assertions are the centre of gravity in social epistemology. They are the vehicles we use to exchange information within scientific groups and society as a whole. It is therefore essential to determine under which conditions we are permitted to make an assertion. In this paper we argue and provide empirical evidence for the view that the norm of assertion is justified belief: truth or even knowledge are not required. Our results challenge the knowledge account advocated by, e.g. Williamson (1996), in (...) general, and more specifically, put into question several studies conducted by Turri (2013, 2016) that support a knowledge norm of assertion. Instead, the justified belief account championed by, e.g. Douven (2006), seems to prevail. (shrink)

Perhaps the most fundamental and distinctive idea of Kantian moral psychology is that no behavior can count as action unless it is performed on a subjective practical principle, or a maxim of action. The maxim is supposed to provide the target of moral assessment of all actions, whether this assessment is prospective or retrospective. The presence of a maxim is also supposed to illuminate how it is that agents are active in, hence responsible for, the peculiar species of events we (...) call actions. To put the point roughly, agents are the sources of their actions in that they have in some sense affirmed or endorsed the maxims of these actions. (shrink)

Do people tend to be overconfident? Many think so. They’ve run studies on whether people are calibrated: whether their average confidence in their opinions matches the proportion of those opinions that are true. Under certain conditions, people are systematically ‘over-calibrated’—for example, of the opinions they’re 80% confident in, only 60% are true. From this empirical over-calibration, it’s inferred that people are irrationally overconfident. My question: When and why is this inference warranted? Answering it requires articulating a general connection between being (...) rational and being right—something extant studies have not done. I show how to do so using the notion of deference. This provides a theoretical foundation for calibration research, but also reveals a flaw: the connection between being rational and being right is much weaker than is standardly assumed, since rational people can often be expected to be miscalibrated. Thus we can’t test whether people are overconfident by simply testing whether they are over-calibrated; instead, we must try to predict the rational deviations from calibration, and then compare those predictions to people’s performance. I show how this can be done—and that doing so complicates the interpretation of robust empirical effects. (shrink)

Like literature and art, music has "works". But not every piece of music is called a work, and not every musical performance is made up of works. The complexities of this situation are explored in these essays, which examine a broad swathe of western music. From plainsong to the symphony, from Duke Ellington to the Beatles, this is at root an investigation into how our minds parcel up the music that we create and hear.

The standard interpretation of quantum mechanics and a standard interpretation of the awareness of pain have a common feature: Both postulate the existence of an irresolvable duality. Whereas many physicists claim that all particles exhibit particle and wave properties, many philosophers working on pain argue that our awareness of pain is paradoxical, exhibiting both perceptual and introspective characteristics. In this chapter, we offer a pessimistic take on the putative paradox of pain. Specifically, we attempt to resolve the supposed paradox by (...) undermining the reasons offered for accepting the introspective side of the dualism. (shrink)

It is widely affirmed that human beings have irreplaceable valuable, and that we owe it to them to treat them accordingly. Many theorists have been drawn to Kantianism because they think that it alone can capture this intuition. One aim of this paper is to show that this is a mistake, and that Kantianism cannot provide an independent rational vindication, nor even a fully illuminating articulation, of irreplaceability. A further aim is to outline a broadly Aristotelian view that provides a (...) more fitting theoretical framework for this appealing conception of human value. This critique of Kantianism extends to contemporary theorists with a broadly Kantian orientation, including Christine Korsgaard, Stephen Darwall and John Rawls. The problem with these views, at heart, is that they attempt to ground morality in respect alone. Yet it is love, not respect, that brings irreplaceability into view. The paper closes with a sketch of a virtue-theoretic theory that follows Aquinas in taking love to be a master virtue that refines the other virtues so as to ensure a continuous and practically efficacious sensitivity to the irreplaceable value of fellow human beings. (shrink)

What is essential to language? Two thinkers active in Vienna in the 1930's, Karl Bühler and Ludwig Wittgenstein, gave apparently incompatible answers to this question. I compare what Wittgenstein says about language and reference at the beginning of his Philosophical Investigations with some aspects of the descriptive analysis of language worked out by Bühler between 1907 and 1934, a systematic development of the philosophies of mind and language of such heirs of Brentano as Martinak, Marty, Meinong, Landgrebe and Husserl. Y (...) a-Uil quelque chose qui est essentiel au langage? Deux penseurs actifs à Vienne dans les années trente, Karl Bühler et Ludwig Wittgenstein, donnent à cette question des réponses qui sont apparemment incompatibles. Je compare ce que Wittgenstein dit du langage et de la référence au début de ses Investigations Philosophiques avec quelques aspects de l'analyse descriptive élaborée par Bühler entre 1907 et 1934, un développement systématique des philosophies de l'esprit et du langage des héritiers de Brentano tels que Martinak, Marty, Meinong, Landgrebe et Husserl. (shrink)

This interview took place through email during October-November, 2019. Michael: It’s a real pleasure to engage you in conversation. You were a foundation member of PESA and someone who in the pre-I...

Suppose that realism about values is true, that there are objects and states of affairs which are intrinsically valuable, that some objects and states of affairs are intrinsically more valuable than others and that some objects and states of affairs are intrinsically valuable for Sam, and others for Maria.

This book aims to develop certain aspects of Gottlob Frege’s theory of meaning, especially those relevant to intensional logic. It offers a new interpretation of the nature of senses, and attempts to devise a logical calculus for the theory of sense and reference that captures as closely as possible the views of the historical Frege. (The approach is contrasted with the less historically-minded Logic of Sense and Denotation of Alonzo Church.) Comparisons of Frege’s theory with those of Russell and others (...) are given. It is in the end shown that developing Frege’s theory in these ways reveals serious problems hitherto largely unnoticed, including those possibly rendering a Fregean intensional logic inconsistent even if his naïve class theory is excluded. (shrink)

Kant maintained that dutiful action can have the fullest measure of moral worth even if chosen in the face of powerful inclinations to act immorally, and indeed that opposing inclinations only highlight the worth of the action. I argue that this conclusion rests on an implausibly mechanistic account of desires, and that many desires are constituted by tendencies to see certain features of one’s circumstances as reasons to perform one or another action. I try to show that inclinations to violate (...) moral requirements sometimes manifest a morally objectionable half-heartedness in one’s commitment to those very requirements, and – by extension – to the values that undergird these requirements. (shrink)

ABSTRACT In a series of papers read to the Cambridge Philosophical Society through the 1820s, the Cambridge mathematician George Peacock laid the foundation for a natural history of arithmetic that would tell a story of human progress from counting to modern arithmetic. The trajectory of that history, Peacock argued, established algebraic analysis as a form of universal reasoning that used empirically warranted operations of mind to think with symbols on paper. The science of counting would suggest arithmetic, arithmetic would suggest (...) arithmetical algebra, and, finally, arithmetical algebra would suggest symbolic algebra. This philosophy of suggestion provided the foundation for Peacock's “principle of equivalent forms,” which justified the practice of nineteenth-century English symbolic algebra. Peacock's philosophy of suggestion owed a considerable debt to the early Cambridge Philosophical Society culture of natural history. The aim of this essay is to show how that culture of natural history was constitutively significant to the practice of nineteenth-century English algebra. (shrink)

One reason that many of the philosophical debates about free will might seem intractable is that di erent participants in those debates use various terms in ways that not only don't line up, but might even contradict each other. For instance, it is widely accepted to understand libertarianism as\the conjunction of incompatibilism [the thesis that free will is incompatible with the truth of determinism] and the thesis that we have free will" (van Inwagen (1983), 13f; see also Kane (2001), 17; (...) Pereboom (2006), xiv). However, for van Inwagen's later reservations about the use of the term `libertarianism', see van Inwagen (2008), relevant pages). This makes perplexing a number of views that have the name `libertarian compatibilism' (see Vihvelin (2000) and Arvan (2013)) as on the standard use of the terms involved, the name appears to involve a contradiction. Even the meaning and usage of the term `free will' is itself contested. Manuel Vargas writes that \`free will' is a term of both ordinary and technical discourse" (Vargas (2013), 325). However, it is not clear if the ordinary use of the term always tracks the technical use. But in an in uential paper on \How to Think about About the Problem of Free Will," Peter van Inwagen claims that \the phrase `free will' . . . hardly exists except as a philosophical term of art. Its non- philosophical uses are pretty much con ned to the phrase `of his/her own free will' which means `uncoerced"' (van Inwagen (2008), 320 footnote 1). To many of us, a look at the philosophical and literatures of the past millennium suggest a use that need not be a technical notion, even if it is often used in a technical way. No matter how this debate about the `ordinary use' of the phrase turns out, recognizing that `free will' gets used in di erent ways and being careful in such usage is important in order to avoid what Chalmers has called `merely verbal disputes' (Chalmers (2011)). For this reason, we want to be very clear in how we understand and de ne free will. There seem to be at least two di erent fundamental notions of what free will is in the contemporary literature. The rst of these, which seems to have garnered the most attention in the last century, works under the assumption that for a person to rightly be said to have free will, she must have the ability 1 to do otherwise than what she does, in fact, do. Under this view I could be said to have freely chosen to drive to work only if I also could have freely chosen, for example, to bike to work or to skip work altogether. This approach to free will is referred to as a `leeway-based approach' (cite my book) or an `alternative- possiblities approach' (see Sartorio (2016).) In contrast, a smaller percentage of the extant literature focuses primarily on the issues of `source,' `ultimacy,' and `origination'. This second approach doesn't focus immediately on the presence or absence of alternative possibilities. On this approach, I freely choose to drive to work only if I am the source of my choice and there is nothing outside of me from which the choice is ultimately derived. In what follows, we refer to the rst of these conceptions|the conception that free will is primarily a matter of having alternative possibilities|as the `leeway- based' conception. Similarly, we will refer to the second of these conceptions| that free will is primarily a matter of our being the source of our choices in a particular way|as the `sourcehood' conception. (John Fischer and Carolina Sartorio refers to sourcehood views as `actual sequence' views; see Fischer (2006) and Sartorio (2016)). Both of these notions can be seen in the following passage taken from Robert Kane: We believe we have free will when we view ourselves as agents ca- pable of in uencing the world in various ways. Open alternatives, or alternative possibilities, seem to lie before us. We reason and deliberate among them and choose. We feel (1) it is `up to us' what we choose and how we act; and this means we could have chosen or acted otherwise. As Aristotle noted: when acting is `up to us,' so is not acting. This `up-to-us-ness' also suggests (2) the ultimate control of our actions lies in us and not outside us in factors beyond our control (Kane (2005), 6). In the next two sections, I look in greater detail at each of these two approaches to the nature of free will, and how they each seek to approach what it means for an action to be `up to us'. I also show how the di erences between these two conceptions cut across the debate about what Kane refers to as the Com- patibility Question: \Is free will compatible with determinism?" (Kane (1996), 13). Along the way, I also brie y point out a number of ways how which of these conceptions is at work shapes how one engages various arguments and other issues regarding. (shrink)

‘What is characteristic of every mental activity’, according to Brentano, is ‘the reference to something as an object. In this respect every mental activity seems to be something relational.’ But what sort of a relation, if any, is our cognitive access to the world? This question – which we shall call Brentano’s question – throws a new light on many of the traditional problems of epistemology. The paper defends a view of perceptual acts as real relations of a subject to (...) an object. To make this view coherent, a theory of different types of relations is developed, resting on ideas on formal ontology put forward by Husserl in his Logical Investigations and on the theory of relations sketched in Smith's "Acta cum fundamentis in re". The theory is applied to the notion of a Cambridge change, which proves to have an unforeseen relevance to our understanding of perception. (shrink)

Niche construction is the process whereby organisms, through their activities and choices, modify their own and each other’s niches. By transforming natural-selection pressures, niche construction generates feedback in evolution at various different levels. Niche-constructing species play important ecological roles by creating habitats and resources used by other species and thereby affecting the flow of energy and matter through ecosystems—a process often referred to as “ecosystem engineering.” An important emphasis of niche construction theory (NCT) is that acquired characters play an evolutionary (...) role through transforming selective environments. This is particularly relevant to human evolution, where our species has engaged in extensive environmental modification through cultural practices. Humans can construct developmental environments that feed back to affect how individuals learn and develop and the diseases to which they are exposed. Here we provide an introduction to NCT and illustrate some of its more important implications for the human sciences. (shrink)

Generic statements (‘Tigers have stripes’) are pervasive and early-emerging modes of generalization with a distinctive linguistic profile. Previous experimental work found that generics display a unique asymmetry between their acceptance conditions and the implications that are typically drawn from them. This paper presents evidence against the hypothesis that only generics display an asymmetry. Correcting for limitations of previous designs, we found a generalized asymmetry effect across generics, various kinds of explicitly quantified statements (‘most’, ‘some’, ‘typically’, ‘usually’), and variations in types (...) of predicated properties (striking vs. neutral). We discuss implications of these results for our understanding of the source of asymmetry effects and whether and in which ways these effects might introduce biased beliefs into social networks. (shrink)