The case study presented by Winch and Sinnott (2011) shows not only how difficult it is for clinicians and researchers to identify conflicts of interest (COI), but also how damaging it can be when there are unin- formed and uncoordinated policy responses by senior administrators.

Launched in 2007, the American Medical Students Association PharmFree Scorecard is an annual ranking of conflict of interest policies at American medical centres; it focuses on COIs that may occur when medical education seems likely to be influenced by university-industry relationships, especially those with the pharmaceutical and medical device industries. The PharmFree Scorecard has proven influential in stimulating changes in policy regarding the management of COI at American medical institutions, thus it provides a useful jumping off point for reflection on (...) how and why medical education institutions in other countries – and for our purposes, Canada – should pay more attention to the appropriate identification and management of COI. The PharmFree Scorecard methodology examines a diversity of factors and interests that could influence medical education; as such, it is an interesting approach to analysing the COI policies of medical schools. To test its utility or applicability outside the US, we decided to apply the PharmFree Scorecard to the COI policies of the 16 Canadian universities hosting medical schools. Overall, Canadian institutions rank very poorly, especially in ensuring that education and training tools are provided to staff, students and faculty members to enable the identification and management of COI. However, differences between the US and Canadian medical education contexts, e.g., with regards to the governance and funding of universities, limit to some extent the direct applicability of the AMSA ranking. Canadian medical schools – and their host universities – nonetheless have much to learn from insights provided by the AMSA PharmFree Scorecard ranking, although they can and should go further in developing their own COI policies and procedures. (shrink)

Research on research ethics—regarding both the governance and practice of the ethical review of human subjects research—has a tumultuous history in North America and Europe. Much of the academic literature focuses on issues to do with regulating the conduct and quality of ethics review of research protocols by ethics committees (research ethics boards (REBs) in Canada and institutional review boards (IRBs) in the United States). In addition, some of the literature attends to issues particular to the review of qualitative research, (...) and still other literature addresses the challenges posed by and the need for research on REBs/IRBs. It is this third group of literature within which our article is situated. (shrink)

Background Next Generation Sequencing (NGS) is expected to help find the elusive, causative genetic defects associated with Bipolar Disorder (BD). This article identifies the importance of NGS and further analyses the social and ethical implications of this approach when used in research projects studying BD, as well as other psychiatric ailments, with a view to ensuring the protection of research participants. Methods We performed a systematic review of studies through PubMed, followed by a manual search through the titles and abstracts (...) of original articles, including the reviews, commentaries and letters published in the last five years and dealing with the ethical and social issues raised by NGS technologies and genomics studies of mental disorders, especially BD. A total of 217 studies contributed to identify the themes discussed herein. Results The amount of information generated by NGS renders individuals suffering from BD particularly vulnerable, and increases the need for educational support throughout the consent process, and, subsequently, of genetic counselling, when communicating individual research results and incidental findings to them. Our results highlight the importance and difficulty of respecting participants’ autonomy while avoiding any therapeutic misconception. We also analysed the need for specific regulations on the use and communication of incidental findings, as well as the increasing influence of NGS in health care. Conclusions Shared efforts on the part of researchers and their institutions, Research Ethics Boards as well as participants’ representatives are needed to delineate a tailored consent process so as to better protect research participants. However, health care professionals involved in BD care and treatment need to first determine the scientific validity and clinical utility of NGS-generated findings, and thereafter their prevention and treatment significance. (shrink)

The culmination of three decades of studying and treating survivors of adult onset trauma, _Wounded by Reality_ is the first systematic attempt to differentiate adult onset trauma from childhood trauma, with which it is frequently confused. When catastrophic events overtake adult lives, they often scar the psyche in ways that psychodynamically oriented clinicians struggle to understand. For Ghislaine Boulanger, the enormous challenge of working with these patients is unsurprising. Survivors of major catastrophe, whether a natural disaster, a life-threatening assault, (...) a serious accident, or an act of terrorism, experience a near-fatal disruption of fundamental aspects of self experience. The sense of agency, of affectivity, of bodily integrity, the capacity for self-reflection, the sense of time, and the ability to relate to others - all are called into question. (shrink)

I call anti-resemblism the thesis that independently of any contextual specification there is no determinate fact of the matter about the comparative overall similarity of things. Anti-resemblism plays crucial roles in the philosophy of David Lewis. For instance, Lewis has argued that his counterpart theory is anti-essentialist on the grounds that counterpart relations are relations of comparative overall similarity and that anti-resemblism is true. After Lewis committed himself to a form of realism about natural properties he maintained that anti-resemblism is (...) true about the relations of overall similarity that enter his counterpart theory and his analysis of counterfactuals. However, in this article I argue that Lewis’s account of degrees of naturalness for properties combined with his modal realism entails that anti-resemblism is false. The Lewisian must amend Lewis’s system if she aims to benefit from the alleged virtues of anti-resemblism. I consider two ways of amending it, neither of which is a free lunch. (shrink)

According to Clifford Geertz, the purpose of anthropology is not to explain culture but to explicate it. That should cause us to rethink our relationship with machine learning. It is, we contend, perfectly possible that machine learning algorithms, which are unable to explain, and could even be unexplainable themselves, can still be of critical use in a process of explication. Thus, we report on an experiment with anthropological AI. From a dataset of 175K Facebook comments, we trained a neural network (...) to predict the emoji reaction associated with a comment and asked a group of human players to compete against the machine. We show that a) the machine can reach the same accuracy as the players, b) it fails in roughly the same ways as the players, and c) easily predictable emoji reactions tend to reflect unambiguous situations where interpretation is easy. We therefore repurpose the failures of the neural network to point us to deeper and more ambiguous situations where interpretation is hard and explication becomes both necessary and interesting. We use this experiment as a point of departure for discussing how experiences from anthropology, and in particular the tension between formalist ethnoscience and interpretive thick description, might contribute to debates about explainable AI. (shrink)

Cet article s’intéresse au marché de l’édition scientifique et à son évolution dans le cadre de l’Internet et du développement du libre accès. Il s’attache à montrer la diversité de ce marché en fonction des champs scientifiques, notamment par le type d’éditeurs impliqués, les lectorats concernés, les économies associées. Il met en exergue le nécessaire discernement de ces marchés face aux critiques générales de dysfonctionnement soulignées. Il pointe certains effets contrastés du numérique conduisant à certaines reconfigurations paradoxales. Enfin, la vision (...) prospective sur le devenir de ce marché insiste sur la pluralité des modalités de progression vers le libre accès, le poids de la dimension politique et celui des processus d’évaluation de la recherche. La voie d’un partenariat public-privé est privilégiée au regard de certaines valeurs centrales : indépendance, qualité, accessibilité et pérennité des publications scientifiques.This article investigates the scientific publishing market and how it is being transformed by the Internet and the development of open-access services. We illustrate the diversity of the market in terms of scientific fields, and especially in the types of publishers and readerships concerned, and of the associated economics. In view of the sweeping criticisms of dysfunctional practices illustrated in the article, we alert readers as to the need for discernment among these markets. The article points to a number of contrasting effects of digital publishing that are leading to various paradoxical reconfigurations. Finally, this forward-looking study of the publishing market’s future emphasises the multiple forms of the onward march towards open access and the influence exerted by the political dimension and the research evaluation process. Public-private partnerships are the preferred option to cater for the central values of independence, quality, accessibility and the enduring nature of scientific publications. (shrink)

This article focuses on defective conditionals ? namely indicative conditionals whose antecedents are false and whose truth-values therefore cannot be determined. The problem is to decide which formal connective can adequately represent this usage. Classical logic renders defective conditionals true whereas traditional mathematics dismisses them as irrelevant. This difference in treatment entails that, at the propositional level, classical logic validates some sentences that are intuitively false in plane geometry. With two proofs, I show that the same flaw is shared by (...) a family of trivalent logics. I go on to examine the strict conditional and its derivatives. This family is the only one to avoid the faulty inference but it does so without addressing the status of the truth-value assigned to defective conditionals. (shrink)

A number of philosophers have recently found it congenial to talk in terms of grounding. Grounding discourse features grounding sentences that are answers to questions about what grounds what. The goal of this article is to explore and defend a counterpart-theoretic interpretation of grounding discourse. We are familiar with David Lewis's applications of the method of counterpart theory to de re modal discourse. Counterpart-theoretic interpretations of de re modal idioms and grounding sentences share similar motivations, mechanisms, and applications. I shall (...) explain my motivations and describe two applications of a counterpart theory for grounding discourse. But, in this article, my main focus is on counterpart-theoretic mechanisms. (shrink)

There is now an awakening to and recognition of the emotionally complex lives of some non-human animals. While their forms of consciousness may vary, some are indeed conscious and deserve political consideration. What that political consideration ought to be is the central topic of this article. First, I argue that interspecies justice must be understood in terms of the relationships that foster individual flourishing of all concerned. The obstacles to such flourishing are the five faces of oppression famously identified by (...) Iris Marion Young: exploitation, marginalization, powerlessness, cultural imperialism, and violence. By extending Young’s concept of the social group to intra- and interspecies groups, we become more attuned to differences between and among species. Theorizing the existence of interspecies groups brings forward new avenues to explore oppression and simultaneously theorize its opposite – interspecies justice. Second, I argue that a positive theory of interspecies flourishing can be developed on the basis of Marx’s materialist philosophy and reclamation of species-being. Though Marx uses humanist language throughout the Economic and Philosophic Manuscripts of 1844, attention to his methodological commitments reveals that some non-human animals can no longer be excluded from the capability of flourishing and species-being. Some non-human animals are conscious, act purposefully, and labor creatively and must be included in our circle of moral and political concern. (shrink)

This article has two goals: a historical and a speculative one. The historical goal is to offer a coherent account of Spinoza’s view on mereological composition. The speculative goal is to show that Spinoza’s substance monism is distinct from versions of monism that are currently defended in metaphysics and that it deserves the attention of contemporary metaphysicians. Regarding the second goal, two versions of monism are currently defended and discussed in contemporary metaphysics: existence monism according to which there actually exists (...) exactly one concrete entity; and priority monism that is famously defended by Jonathan Schaffer and according to which there exists exactly one fundamental concrete being, the cosmos, and several derivative concrete beings that are the parts of the cosmos. In this article, I argue that substance monism is neither an existence nor a priority monism because, while Spinoza’s monist is committed to the existence of a unique fundamental individual—the substance—and to the existence of several derivative individuals—the bodies or modes of extension—, Spinoza denies that the substance is mereologically complex. Regarding the first goal, the paper solves several interpretative puzzles by arguing that Spinoza distinguishes between three kinds of composition and that his talk of composition between the substance and its modes is by his own light not to be interpreted as literally true. (shrink)

Bringing Pierre Bourdieu to Science and Technology Studies Content Type Journal Article Pages 263-273 DOI 10.1007/s11024-011-9174-2 Authors Mathieu Albert, Wilson Centre and Department of Psychiatry, Faculty of Medicine, University of Toronto, 200 Elizabeth Street , Eaton-South 1-581, Toronto, ON M5G 2C4, Canada Daniel Lee Kleinman, Department of Community and Environmental Sociology, University of Wisconsin-Madison, 348 Agricultural Hall 1450 Linden Drive, Madison, WI 53706, USA Journal Minerva Online ISSN 1573-1871 Print ISSN 0026-4695 Journal Volume Volume 49 Journal Issue Volume 49, (...) Number 3. (shrink)

This chapter explores an objection to explanatory universalism, the doctrine that the principle of sufficient reason is true or everything has an explanation. This objection is a direct argument to the conclusion that the PSR yields the existence of an omni-explainer, i.e. something that explains everything. The objection crucially relies on the assumption that explanation is dissective in its explanandum place, and its conclusion conflicts with the irreflexivity of explanation. So the chapter considers two responses to the mentioned objection. The (...) first response consisting in restricting the irreflexivity of explanation is criticised in connection with topics in the metaphysics of grounding. The second response consisting in denying that explanation is dissective is vindicated. Finally, the chapter argues that a plausible revised version of the principle that explanation is dissective, the PSR, and the irreflexivity of explanation together yield a striking picture of our universe. (shrink)

This article maps a controversy in network science over the last 15 years, dividing the field about the epistemic status of a central notion, scale-freeness. The article accounts for the two main disputes, in 2005 and in 2018, as they unfolded in academic publications and on social media. This article analyzes the conflict, and the reasons why it reignited in 2018, to the surprise of many. It is argued that the concept of complex networks is shared by the distinct subcultures (...) of theorists and experimentalists; and that these subcultures have incompatible approaches to knowledge: nomothetic and idiographic. Following Galison, this article contends that network science is a trading zone where theorists and experimentalists can trade knowledge across the epistemic divide. (shrink)

This article defends the principle of sufficient reason (PSR) from a simple and direct valid argument according to which PSR implies that there is a truth that explains every truth, namely an omni-explainer. Many proponents of PSR may be willing to bite the bullet and maintain that, if PSR is true, then there is an omni-explainer. I object to this strategy by defending the principle that explanation is irreflexive. Then I argue that proponents of PSR can resist the conclusion that (...) there is an omni-explainer by denying that explanation distributes over conjunction. In the final section, I consider a plausible revision of this assumption. I argue there that, given the revised assumption, PSR seems to yield a striking picture of the explanatory structure of the universe. I explain why the resulting model does not appear utterly implausible to me. (shrink)

A Polish space is not always homeomorphic to a computably presented Polish space. In this article, we examine degrees of non-computability of presenting homeomorphic copies of compact Polish spaces. We show that there exists a $\mathbf {0}'$ -computable low $_3$ compact Polish space which is not homeomorphic to a computable one, and that, for any natural number $n\geq 2$, there exists a Polish space $X_n$ such that exactly the high $_{n}$ -degrees are required to present the homeomorphism type of $X_n$. (...) Along the way we investigate the computable aspects of Čech homology groups. We also show that no compact Polish space has a least presentation with respect to Turing reducibility. (shrink)

Résumé La collaboration avec une chorégraphe engage une réévaluation du travail de sculpture. Cette interprétation débouche sur des formes nouvelles par l’intermédiaire de sculptures animées qui s’apparentent à des formes de marionnettes.

This chapter is concerned with the coextension difficulty for nominalist theories of properties that reject tropes alongside universals. After carefully explaining the coextension difficulty and describing the theories it targets, the chapter describes different solutions to the difficulty. These solutions differ with respect to how much involved they are into a dualist approach to coextension. A dualist approach to a case of coextension consists in agreeing with the realist that the relevant ascriptions of properties are numerically distinct. A monist approach (...) to a case of coextension consists in contending that the relevant ascriptions of properties are identical. In this chapter, I defend a monist approach to cases of coextension that appeals to a counterpart theory for propositions. (shrink)

Church and Fitch have argued that from the verificationationist thesis “for every proposition, if this proposition is true, then it is possible to know it” we can derive that for every truth there is someone who knows that truth. Moreover, Humberstone has shown that from the latter proposition we can derive that someone knows every truth, hence that there is an omniscient being. In his article “Omnificence”, John Bigelow adapted these arguments in order to argue that from the assumption "every (...) contingent proposition is such that if it is true something brought it about that it is true" we can derive that there is an omnificent being: a being that brings it about that every true contingent proposition is true. In my reply to his article, I show that Bigelow’s argument is flawed because there is some formal property that the knowledge operator has but that the bringing about operator lacks. This is the property of distributing over conjunctions. I explain why what brings it about that some conjunctive proposition is true need not bring it about that its conjuncts are true. (shrink)

This paper argues that most contemporary accounts of weakness of will either implicitly or explicitly assume that regret is a typical or even necessary element of standard cases of weakness of will and that this assumption is mistaken. I draw on empirical and philosophical work on self-assessment to show that regret need not accompany typical weak-willed behavior, and that we should therefore revise the dominant account of the difference between weakness of will and changes of mind.

Research has shown that context influences how sincere a smile appears to observers. That said, most studies on this topic have focused exclusively on situational cues (e.g. smiling while at a party versus smiling during a job interview) and few have examined other elements of context. One important element concerns any knowledge an observer might have about the smiler as an individual (e.g. their habitual behaviours, traits or attitudes). In this manuscript, we present three experiments that explored the influence of (...) such knowledge on ratings of smile sincerity. In Experiments 1 and 2, participants rated the sincerity of Duchenne and non-Duchenne smiles after having been exposed to cues about the smiler’s tendency to reciprocate (this person always, never or occasionally returns favours). In Experiment 3 they performed the same task but with cues about the smiler’s love of learning (this person always, never or occasionally enjoys learning new tasks). The results show that cues about the smiler’s reciprocity tendency influenced participants’ ratings of smile sincerity and did so in a stronger manner than cues about the smiler’s love of learning. Overall, these results both strengthen and broaden the literature on the role of context on judgements of smile sincerity. (shrink)

Thesis (Ph.D, Philosophy) -- Queen's University, 2009-08-31 12:18:30.156.

We present the inconsistency-adaptive deontic logic DP r , a nonmonotonic logic for dealing with conflicts between normative statements. On the one hand, this logic does not lead to explosion in view of normative conflicts such as O A ∧ O ∼A, O A ∧ P ∼A or even O A ∧ ∼O A. On the other hand, DP r still verifies all intuitively reliable inferences valid in Standard Deontic Logic (SDL). DP r interprets a given premise set ‘as normally (...) as possible’ with respect to SDL. Whereas some SDL-rules are verified unconditionally by DP r , others are verified conditionally. The latter are applicable unless they rely on formulas that turn out to behave inconsistently in view of the premises. This dynamic process is mirrored by the proof theory of DP r. (shrink)

It is widely agreed that properties play causal roles: they capture the causal powers of things. But do properties have their causal roles essentially? David Lewis did not think so. He adhered to the doctrine of quidditism, namely the doctrine that the identity of properties is primitive and that they can trade their causal roles. Quidditism is controversial. But Lewis did not see why he should want to reject it. He knew that he could avoid quidditism on the cheap by (...) treating individuals and properties alike in rejecting transworld multilocation of properties and endorsing a counterpart theory for properties. But he did not see why he should want to do so. In this article, I argue that Lewis should have wanted to endorse a counterpart theory for properties in order to reject quidditism. My argument concerns resemblance relations among properties. Another constitutive role of properties is that they capture objective resemblances between their instances. The premises of my argument are intuitive claims about resemblances among some properties that Lewis held on Humean grounds. (shrink)

This book offers a comparative study of the management of legal pluralism. The authors describe and analyse the way state and non-state legal systems acknowledge legal pluralism - defined as the coexistence of a state and non-state legal systems in the same space in respect of the same subject matter for the same population - and determine its consequences for their own purposes. The book sheds light on the management processes deployed by legal systems in Africa, Canada, Central Europe and (...) the South Pacific, the multitudinous factors circumscribing the action of systems and individuals with respect to legal pluralism, and the effects of management strategies and processes on systems as well as on individuals. The book offers fresh practical and analytical insight on applied legal pluralism, a fast-growing field of scholarship and professional practice. Drawing from a wealth of original empirical data collected in several countries by a multilingual and multidisciplinary team, it provides a thorough account of the intricate patterns of state and non-state practices with respect to legal pluralism. As the book's non-prescriptive approach helps to uncover and evaluate several biases or assumptions on the part of policy makers, scholars and development agencies regarding the nature and the consequences of legal pluralism, it will appeal to a wide range of scholars and practitioners in law, development studies, political science and social sciences. (shrink)

We present two defeasible logics of norm-propositions (statements about norms) that (i) consistently allow for the possibility of normative gaps and normative conflicts, and (ii) map each premise set to a sufficiently rich consequence set. In order to meet (i), we define the logic LNP, a conflict- and gap-tolerant logic of norm-propositions capable of formalizing both normative conflicts and normative gaps within the object language. Next, we strengthen LNP within the adaptive logic framework for non-monotonic reasoning in order to meet (...) (ii). This results in the adaptive logics LNPr and LNPm, which interpret a given set of premises in such a way that normative conflicts and normative gaps are avoided ‘whenever possible’. LNPr and LNPm are equipped with a preferential semantics and a dynamic proof theory. (shrink)

This paper is going to discuss, what will be called, ‘The Internet of Bodies’. Our physical and virtual worlds are blending and shifting our understanding of three key areas: (1) our identities are diversifying, as they become hyper-enhanced and multi-sensory; (2) our collaborations are co-created, immersive and connected; (3) our innovations are diverse and inclusive. It is proposed that our bodies have finally become the interface.

This paper presents the first possible world semantics for concessive conditionals (i.e., even if A, C conditionals) constructed in a compositional way. First, the meaning of if is formalized through a semantics that builds on the proposal given by Stalnaker (1968). A major difference from Stalnaker’s approach is that irrelevant conditionals (i.e., conditionals where the antecedent and the consequent have no connection) are false in this new setting. Second, the meaning of even is analyzed through a formal semantics based on (...) the notion of scale. This analysis overcomes the problems arising in standard approaches, in which even is analyzed with the help of pragmatic presuppositions. Finally, the two particles are combined in order to provide a formal analysis of even if. This theory predicts the major phenomena concerning the behavior of concessive conditionals and without any call to pragmatic explanations. More generally, this approach creates the possibility of a compositional analysis of other conditionals such as if then or only if forms. (shrink)