The prospect of using cell-based interventions to treat neurological conditions raises several important ethical and policy questions. In this target article, we focus on issues related to the unique constellation of traits that characterize CBIs targeted at the central nervous system. In particular, there is at least a theoretical prospect that these cells will alter the recipients' cognition, mood, and behavior—brain functions that are central to our concept of the self. The potential for such changes, although perhaps remote, is cause (...) for concern and careful ethical analysis. Both to enable better informed consent in the future and as an end in itself, we argue that early human trials of CBIs for neurological conditions must monitor subjects for changes in cognition, mood, and behavior; further, we recommend concrete steps for that monitoring. Such steps will help better characterize the potential risks and benefits of CBIs as they are tested and potentially used for treatment. (shrink)

These new translations of two treatises dealing with the possibility and nature of knowledge in the face of skeptical challenges are the first to be rendered from the Latin critical edition, the first to be made specifically with a philosophical audience in mind, and the first to be translated by a scholar with expertise in both modern epistemology and philosophy of language.

A school of thought traceable to the political writings of Bodin and Hobbes believes that "order" is the cardinal principle which takes precedence over "justice" - which is reduced to conformity. The main concern of this book is to analyse this tradition through study of its progenitors.

Academic discussion of pornography is generally restricted to issues arising from the depiction of adults. I argue that child-pornography is a more complex matter, and that generally accepted moral judgements concerning pornography in general have to be revised when children are involved. I look at the question of harm to the children involved, the consumers, and society in general, at the question of blame, and at the possibility of a morally acceptable form of child-pornography. My approach involves an objectivist meta-ethics (...) and a utilitarian view of practical ethics, and I bring out the advantages of these theories to the consideration of moral issues such as this one. (shrink)

If stem cell-based therapies are developed, we will likely confront a difficult problem of justice: for biological reasons alone, the new therapies might benefit only a limited range of patients. In fact, they might benefit primarily white Americans, thereby exacerbating long-standing differences in health and health care.

In one corner Socrates; in the other, on the mat, his cat Felix. Socrates, of course, thinks (correctly) that Felix the Cat is on the mat. But there’s the rub. For Socrates to think that Felix is on the mat, he has to be able to think about Felix, that is, he has to have some sort of cognitive grasp of an individual — and not just any individual, but Felix himself. How is that possible? What is going on when (...) we think about things? (shrink)

Mediaeval psychological theory was a “faculty psychology”: a confederation of semiautonomous sub-personal agents, the interaction of which constitutes our psychological experience. One such faculty was intellective appetite, that is, the will. On what grounds was the will taken to be a distinct faculty? After a brief survey of Aristotle's criteria for identifying and distinguishing mental faculties, I look in some detail at the mainstream mediaeval view, given clear expression by Thomas Aquinas, and then at the dissenting views of John Duns (...) Scotus and William of Ockham. I conclude with some reflections on why the mainstream mediaeval view was discarded by Descartes. (shrink)

Philosophical work on testimony has flourished in recent years. Testimony roughly involves a source affirming or stating something in an attempt to transfer information to one or more persons. It is often said that the topic of testimony has been neglected throughout most of the history of philosophy, aside from contributions by David Hume (1711–1776) and Thomas Reid (1710–1796).1 True as this may be, Hume and Reid aren’t the only ones who deserve a tip of the hat for recognizing the (...) importance of testimony: St. Augustine of Hippo (354–430) affirms the place of testimony in human cognition, at least in his later writings. (shrink)

The information‐transference account of teaching takes it to be a process in which information is transferred from one person's mind to another's. Augustine argues that this is impossible, since in order to understand something the person who understands must come to see why it is so, and that is an internal episode of awareness that isn't caused by an outside source. Augustine's insight here is contrasted with the contemporary view, following Wittgenstein, that learning is a matter of conformity to rules (...) (public norms). The case is made that teaching and learning pose philosophical problems that contemporary theories don't address, and a brief examination of Searle's Chinese Room example suggests that its plausibility derives from Augustine's insight that mere rule‐following behavior isn't enough to explain the phenomenon of understanding at the heart of knowledge. A reconstruction of Augustine's epistemological claims, divorced from his discredited views in the philosophy of language, is also provided. (shrink)

[1] In twelve quite demanding chapters, outstanding scholars provide an overall view of the key issues of Scotus’s philosophical thought. To this a very concise introduction is added, concerning the life and works of John Duns (very good, especially the survey of works and the information on critical editions etc.). Throughout the book, I find the information clear and the difficult topics well explained. Moreover, the volume gives a quick entrance to the vast literature. Among the topics discussed are: ‘Metaphysics’ (...) (Peter King), ‘Universals and Individuation’ (Timothy Noone), ‘Modal Theory’ (Calvin Normore), ‘Natural Theology’ (James Ross & Todd Bates), ‘Philosophy of Mind’ (Richard Cross), ‘Cognition’ (Robert Pasnau), ‘Moral Dispositions’ (Bonnie Kent). What strikes the eye is the absence of important theological subjects: Trinity, Christology, sin and grace, to name a few. Since the cover text promises that ‘the essays in this volume systematically survey the full range of Scotus’ thought’, this omission is remarkable. It stems, I guess, from the strict philosophical scope of the series of the Cambridge Companions, but such a limitation should have been recognised explicitly: this companion provides, in fact, an introduction to John Duns’s philosophy—i.e., philosophy in our modern sense. Of course, this separation of philosophical from theological thought is not from Scotus. Most of his innovative ‘philosophical’ ideas are developed in a profoundly theological context! (shrink)

Wilfrid Sellars charged that mediaeval philosophers confused the genuine intentionality of thinking with what he called the “pseudo-intentionality” of sensing. I argue that Sellars’s charge rests on importing a form of mind/body dualism that was foreign to the Middle Ages, but that he does touch on a genuine difficulty for mediaeval theories, namely whether they have the conceptual resources to distinguish between intentionality as a feature of consciousness and mere discriminative responses to the environment. In the end, it seems, intentionality (...) cannot be “the mark of the mental” as contemporary philosophy usually takes it. (shrink)

Peter Abelard (1079 – 21 April 1142) [‘Abailard’ or ‘Abaelard’ or ‘Habalaarz’ and so on] was the pre-eminent philosopher and theologian of the twelfth century. The teacher of his generation, he was also famous as a poet and a musician. Prior to the recovery of Aristotle, he brought the native Latin tradition in philosophy to its highest pitch. His genius was evident in all he did. He is, arguably, the greatest logician of the Middle Ages and is equally famous as (...) the first great nominalist philosopher. He championed the use of reason in matters of faith (he was the first to use ‘theology’ in its modern sense), and his systematic treatment of religious doctrines are as remarkable for their philosophical penetration and subtlety as they are for their audacity. Abelard seemed larger than life to his contemporaries: his quick wit, sharp tongue, perfect memory, and boundless arrogance made him unbeatable in debate — he was said by supporter and detractor alike never to have lost an argument — and the force of his personality impressed itself vividly on all with whom he came into contact. His luckless affair with Héloïse made him a tragic figure of romance, and his conflict with Bernard of Clairvaux over reason and religion made him the hero of the Enlightenment. For all his colourful life, though, his philosophical achievements are the cornerstone of his fame. (shrink)

Professor King's concept of the philosophy of history leads him to offer this demonstration of the incoherence, even absurdity, of the notion that the past can have nothing to teach us - whether posed by those who argue that history is "unique" or that it is merely "contextual".

In his commentary on Aristotle’s Peri hermeneias,1 Abelard distinguishes the form of an expression2 (oratio) from what it says, that is, its content. The content of an expression is its understanding (intellectus). This distinction is surely the most well-known and central idea in Abelard’s commentary. It provides him with the opportunity to distinguish statements (enuntiationes) from other kinds of expressions without implying a diference in their content, since the ability of a statement to signify something true or false (verum vel (...) falsum)3 cannot be found in its content. More precisely, Abelard distinguishes statements both from complete expressions (orationes perfectae) that are not statements but rather questions, requests, commands, etc. and from incomplete expressions, that is, mere word strings (orationes imperfectae), such as homo albus. These kinds of expressions, according to Abelard, do not differ in the understanding they present but in the way they present it. (shrink)

One answer: Because medieval philosophy is just the continuation of ancient philosophy by other means—the Latin language and the Catholic Church— and, as Wallace Matson pointed out some time ago, the mind-body problem isn’t ancient.

Children therefore, whether they be brought up and preserved by the father, or by the mother, or by whomsoever, are in most absolute subjection to him or her, that so bringeth them up, or preserveth them. And they may alienate them, that is, assign his or her dominion, by selling, or giving them, in adoption or servitude to others; or may pawn them for hostages, kill them for rebellion, or sacrifice them for peace, by the law of nature, when he (...) or she, in his or her conscience, think it to be necessary. —The Elements of Law 23.8.. (shrink)

I argue that Abelard was the author of the first theory of mental language in the Middle Ages, devising a “language of thought” to provide the semantics for ordinary languages, based on the idea that thoughts have linguistic character. I examine Abelard’s semantic framework with special attention to his principle of compositionality (the meaning of a whole is a function of the meanings of the parts); the results are then applied to Abelard’s distinction between complete and incomplete expressions, as well (...) as the distinction between sentences and the statements which the sentences are used to make. Abelard’s theory of mental language is shown to be subtle and sophisticated, the forerunner of the great theories of the fourteenth century. (shrink)

ABELARD'S ethical theory, presented above all in his Ethics, is a version of what I'll call intentionalism': the view that the agent's intention determines the moral worth of an action. Now even in Abelard's day, the common understanding of morality seemed to endorse the following principle: (P) An agent should intend to Φ only if bringing about Φ would be good -/- But Abelard replaces (P) with its obverse, a principle he identifies as the rational core imbedded in traditional Christian (...) moral teaching: (P*) An agent should bring about Φ only if intending to Φ would be good Abelard's arguments against (P) and in support of (P*) are remarkably similar to those given by the most famous exponent of intentionalism, Kant. For Kant's ethical theory, especially as he presents in the first section of the Groundwork of the Metaphysics of Morals, identifies (P*) as the philosophical conception corresponding to the "common rational knowledge of morals." Abelard and Kant locate moral worth in features of the way the agent conceptualizes her performances, and each thinks that goodness is characterizable in terms of the form such conceptualization takes. Both are deeply indebted to Stoic ethics, familiar to each largely through Seneca's letters, and they share a common project: 'christianizing' Stoic metaethics so that the classical equation of virtue with happiness is revised to leave room for God and the Afterlife. -/- I'l l proceed as follows. In §1, Abelard's arguments against (P) will be canvassed. In §2, I'l l look at his arguments in favor of (P*) and a 'mediaeval categorical imperative'. In §3, a comparison with Kant's intentionalism should make the virtues of Abelard's theory apparent. In §4, I'l l discuss Abelard's failed attempt to baptize Stoicism. Finally, by way of conclusion, I'll offer a suggestion about why intentionalism, in any of its versions, is an ethical theory to take seriously. (shrink)

The works translated here deal with two major themes in the thinking of St Augustine : free will and divine grace. On the one hand, free will enables human beings to make their own choices; on the other hand, God's grace is required for these choices to be efficacious. 'On the Free Choice of the Will', 'On Grace and Free Choice', 'On Reprimand and Grace' and 'On the Gift of Perseverance' set out Augustine's theory of human responsibility, and sketch a (...) subtle reconciliation of will and grace. This volume is the first to bring together Augustine's early and later writings on these two themes, in a new translation by Peter King, enabling the reader to see what Augustine regarded as the crowning achievement of his work. The volume also includes a clear and accessible introduction that analyzes Augustine's key philosophical lines of thought. (shrink)

State Medical Boards (SMBs) can take severe disciplinary actions (e.g., license revocation or suspension) against physicians who commit egregious wrongdoing in order to protect the public. However, there is noteworthy variability in the extent to which SMBs impose severe disciplinary action. In this manuscript, we present and synthesize a subset of 11 recommendations based on findings from our team’s larger consensus-building project that identified a list of 56 policies and legal provisions SMBs can use to better protect patients from egregious (...) wrongdoing by physicians. (shrink)

stance, Scotus adopts Anselm’s notion of a ‘(pure) perfection’ and elevates it to a fundamental principle of his metaphysics. Again, he distills Anselm’s Ontological Argument into something like its original Monologion components, and then treats each component part of the argument with a rigor and attention to detail far beyond anything Anselm suggested. In the case of Anselm’s so-called ‘two-wills’ theory, however, Scotus’s revisions are so extensive that they amount to a rejection of Anselm’s account, even though Scotus retains some (...) of Anselm’s terminology. I’ll begin by looking at Anselm’s initial presentation of the two-wills theory in his De casu diaboli (§1), and his later refinements of that account in his De concordia (§2). I’ll then look at Scotus’s deployment, revision, and rejection of Anselm’s theory in his three discussions of angelic sin: Lect. 2 d. 6 q. 2 (§3), Ord. 2 d. 6 q. 2 (§4), and Rep. 2 d. 6 q. 2 (§5). This will be followed by a brief look at whether Scotus’s theory of the self-regulating will is an adequate replacement for Anselm’s account (§6). (shrink)

We report on the deliberations of an interdisciplinary group of experts in science, law, and philosophy who convened to discuss novel ethical and policy challenges in stem cell research. In this report we discuss the ethical and policy implications of safety concerns in the transition from basic laboratory research to clinical applications of cell-based therapies derived from stem cells. Although many features of this transition from lab to clinic are common to other therapies, three aspects of stem cell biology pose (...) unique challenges. First, tension regarding the use of human embryos may complicate the scientific development of safe and effective cell lines. Second, because human stem cells were not developed in the laboratory until 1998, few safety questions relating to human applications have been addressed in animal research. Third, preclinical and clinical testing of biologic agents, particularly those as inherently complex as mammalian cells, present formidable challenges, such as the need to develop suitable standardized assays and the difficulty of selecting appropriate patient populations for early phase trials. We recommend that scientists, policy makers, and the public discuss these issues responsibly, and further, that a national advisory committee to oversee human trials of cell therapies be established. **NB we did not reccommend a NAC, we think it might be appropriate**. (shrink)

Since the beginning of the AIDS epidemic, the proportion of AIDS cases among women has continued to rise. Women constituted 23 percent of the AIDS cases reported to the Centers for Disease Control and Prevention in 1995, and 81 percent of these women were of childbearing age. It was not until 1991, however, that epidemiological studies of women were initiated. By comparison, the representation of HIV-infected women in clinical trials gradually has grown. Undoubtedly, a consequence of the increased numbers of (...) women in clinical and epidemiological research is the earlier identification of and more appropriate treatments for HIV-related syndromes when women present in the clinical setting. Despite this expanded focus on women, however, clear information to guide the treatment of HIV-infected women who are pregnant is still lagging behind. (shrink)

Since the beginning of the AIDS epidemic, the proportion of AIDS cases among women has continued to rise. Women constituted 23 percent of the AIDS cases reported to the Centers for Disease Control and Prevention in 1995, and 81 percent of these women were of childbearing age. It was not until 1991, however, that epidemiological studies of women were initiated. By comparison, the representation of HIV-infected women in clinical trials gradually has grown. Undoubtedly, a consequence of the increased numbers of (...) women in clinical and epidemiological research is the earlier identification of and more appropriate treatments for HIV-related syndromes when women present in the clinical setting. Despite this expanded focus on women, however, clear information to guide the treatment of HIV-infected women who are pregnant is still lagging behind. (shrink)

introduced the concept of effective demand in the nascent science of economics; his discussions of astronomy were acute enough to raise Duhem’s interest. Neither are Buridan’s credentials as a nominalist in doubt, although investigation into his precise relation to William of Ockham continues: he rejected all abstract entities, whether universals, common natures, the complexe significabile, or types above and beyond tokens; for Buridan, every thing which exists is a concrete individual. His anti-realism included an epistemological component as well, for Buridan (...) maintained that the source of all knowledge is experience. (shrink)

Thomas Hobbes is arguably the greatest of all English philosophers. In the second half of the twentieth century, he has been the subject of sustained critical attention. Hobbes was capable of powerful argument on virtually any level, whether logical, scriptural or historical. And he has attracted attention in all these areas and more questions of historical method, language and linguistics, metaphysics, ethics, law, politics, science and religion. Hobbes has been examined from a great variety of perspectives as an ethical positivist (...) and a deontologist, as a bourgeois advocate and a supporter of the aristocracy, as an absolutist and a proponent of parliamentary government, as a "conservative" and a "modern," as an atheist and a believer. The periodical literature on Hobbes is accordingly very rich, but it is also difficult to access. The four volumes of these critical assessments assemble an important array of material which will be invaluable to all students of Hobbes. (shrink)

Philosophiques 32 (2005), 435-447. [An English version is available here.].

Complete moral consensus on the status of the human embryo is neither feasible nor necessary for the formulation of ethically acceptable public policy for human embryo research. Significant consensus on permissible human embryo research can rest upon diverse but overlapping moral traditions. Thus, human embryo research policy should do more than reflect mere abstract assertions about the moral status of human embryos. Rather, the moral underpinnings of human embryo research should be derived from a range of values, including the facilitation (...) of human procreation, the advancement of applied scientific knowledge, the reduction of human suffering, and the protection of vulnerable persons from coercion and exploitation. (shrink)

Martin Luther King’s primary emphasis was upon ‘beloved community,’ a phrase he borrowed from Royce, but an idea that he shared with St. Augustine. Theories of the state tend to focus upon division, in which one stratum dominates another or others. King’s context is the US in the segregated South—a region whose internal divisions sharply instantiate the idea of the state as an unequal hierarchy of dominance. King’s appeal was less to end black subjugation than to end subjugation as such. (...) Hence King was called by some a ‘dreamer,’ given his background commitment to equality and community, ideals taking marginal precedence over his foreground commitment to liberty and autonomy. This article explores the notion of ‘beloved community’ broadly and then specifically in Martin Luther King along with related notions in Howard Thurman and in Josiah Royce. (shrink)