Human–Human and Human–Robot Interaction are known to be influenced by a variety of modalities and parameters. Nevertheless, it remains a challenge to anticipate how a given mobile robot’s navigation and appearance will impact how it is perceived by humans. Drawing a parallel with vocal prosody, we introduce the notion of movement prosody, which encompasses spatio-temporal and appearance dimensions which are involved in a person’s perceptual experience of interacting with a mobile robot. We design a novel robot motion corpus, encompassing variables (...) related to the kinematics, gaze, and appearance of the robot, which we hypothesize are involved in movement prosody. Initial results of three perception experiments suggest that these variables have significant influences on participants’ perceptions of robot socio-affects and physical attributes. (shrink)

Breaking off the ordinary flow of experience, the passions create a state of exception. In their suddenness and intensity, they map a personal world, fix and qualify our attention, and impel our actions. Outraged anger drives us to write laws that will later be enforced by impersonal justice. Intense grief at the death of someone in our life discloses the contours of that life to us. Wonder spurs scientific inquiry. The strong current of Western thought that idealizes a dispassionate world (...) has ostracized the passions as quaint, even dangerous. Intense states have come to be seen as symptoms of pathology. A fondness for irony along with our civic ideal of tolerance lead us to prefer the diluted emotional life of feelings and moods. Demonstrating enormous intellectual originality and generosity, Philip Fisher meditates on whether this victory is permanent-and how it might diminish us. From Aristotle to Hume to contemporary biology, Fisher finds evidence that the passions have defined a core of human nature no less important than reason or desire. Traversing the Iliad, King Lear, Moby Dick, and other great works, he discerns the properties of the high-spirited states we call the passions. Are vehement states compatible with a culture that values private, selectively shared experiences? How do passions differ from emotions? Does anger have an opposite? Do the passions give scale, shape, and significance to our experience of time? Is a person incapable of anger more dangerous than someone who is irascible? In reintroducing us to our own vehemence, Fisher reminds us that it is only through our strongest passions that we feel the contours of injustice, mortality, loss, and knowledge. It is only through our personal worlds that we can know the world. (shrink)

Futurists have imagined the Internet as a separate “cyberspace” and as a force for an idealized marketplace. Business practice and economic theory, however, lead to a different picture. (1) “Always-on” connections bring new interface problems and social skills. (2) Reduced transaction costs and increased economies of scale bring outsourcing, concentration, and globalized economy of focused monopolies. (3) The economies of scope inherent in modular computing systems bring “shallow diversity”: processes and products generated by a common underlying framework. This new picture (...) omits many countervailing factors. Even so, the very existence of alternative scenarios should sharpen questions for research. (shrink)

W.V.O.Quine’s doctrine of referential inscrutability (RI) is the thesis that, first, linguistic reference must always be determined relative to an interpretation of the discourse and, second, that the empirical evidence always underdetermines our choice of interpretation--at least in principle. Although this thesis is a central result of Quine’s theory of language, it was long unclear just how much force RI actually carried. At best, Quine’s discussions provided localized examples of RI (e.g., ‘gavagai’), supplemented merely by arguments for the (in principle) (...) constructability of more general referentially divergent manuals. In defense of Quine, Gerald Massey provides a method for generating large-scale referentially divergent manuals for a complex language. I argue that, while Massey’s rival manuals do meet Quine’s translational criteria, they are demonstrably inferior to their commonsensical “homophonic” competitor. This result provides a clear indication of seminal deficiencies in Quine’s behaviorial approach to the theory of language. Next I argue that Quine’s acceptance of standard assumptions about the nature of perception strongly influences the shape of his semantical theory. Finally, I suggest how an alternative to the standard account of perception might provide grounds for a more adequate understanding of language. (shrink)

There is conflicting experimental evidence about whether the “stakes” or importance of being wrong affect judgments about whether a subject knows a proposition. To date, judgments about stakes effects on knowledge have been investigated using binary paradigms: responses to “low” stakes cases are compared with responses to “high stakes” cases. However, stakes or importance are not binary properties—they are scalar: whether a situation is “high” or “low” stakes is a matter of degree. So far, no experimental work has investigated the (...) scalar nature of stakes effects on knowledge: do stakes effects increase as the stakes get higher? Do stakes effects only appear once a certain threshold of stakes has been crossed? Does the effect plateau at a certain point? To address these questions, we conducted experiments that probe for the scalarity of stakes effects using several experimental approaches. We found evidence of scalar stakes effects using an “evidence seeking” experimental design, but no evidence of scalar effects using a traditional “evidence-fixed” experimental design. In addition, using the evidence-seeking design, we uncovered a large, but previously unnoticed framing effect on whether participants are skeptical about whether someone can know something, no matter how much evidence they have. The rate of skeptical responses and the rate at which participants were willing to attribute “lazy knowledge”—that someone can know something without having to check—were themselves subject to a stakes effect: participants were more skeptical when the stakes were higher, and more prone to attribute lazy knowledge when the stakes were lower. We argue that the novel skeptical stakes effect provides resources to respond to criticisms of the evidence-seeking approach that argue that it does not target knowledge. (shrink)

We interpret the probability rule of the CSL collapse theory to mean to mean that the scalar field which causes collapse is the gravitational curvature scalar with two sources, the expectation value of the mass density (smeared over the GRW scale a) and a white noise fluctuating source. We examine two models of the fluctuating source, monopole fluctuations and dipole fluctuations, and show that these correspond to two well-known CSL models. We relate the two GRW parameters of CSL to fundamental (...) constants, and we explain the energy increase of particles due to collapse as arising from the loss of vacuum gravitational energy. (shrink)

The 2006 outbreak of E. coli O157:H7, traced to bagged spinach from California, illustrates a number of contradictions. The solutions sought by many politicians and popular food analysts have been to create a centralized federal agency and a uniform set of production standards modeled after those of the animal industry. Such an approach would disproportionately harm smaller-scale producers, whose operations were not responsible for the epidemic, as well as reduce the agroecological diversity that is essential for maintaining healthy human beings (...) and ecosystems. Why should responses that only reinforce the problem be proffered? We use the framework of accumulation and legitimation to suggest corporate and government motives for concealing underlying problems and reinforcing powerful ideologies of individualism, scientism, and centralizing authority. Food safety (or the illusion of safety) is being positioned to secure capital rather than public welfare. We propose implementing the principle of subsidiarity as a more democratic and decentralized alternative. Because full implementation of this principle will be resisted by powerful interests, some promising intermediate steps include peer production or mass collaboration as currently applied to disease prevention and surveillance, as well as studying nascent movements resisting current food safety regulations. (shrink)

We discuss the circumstances under which gravity might be repulsive rather than attractive. In particular we show why our standard solar system distance scale gravitational intuition need not be a reliable guide to the behavior of gravitational phenomena on altogether larger distance scales such as cosmological, and argue that in fact gravity actually gets to act repulsively on such distance scales. With such repulsion a variety of current cosmological problems (the flatness, horizon, dark matter, universe age, cosmic acceleration (...) and cosmological constant problems) are then all naturally resolved. (shrink)

We discuss some outstanding open questions regarding the validity and uniqueness of the standard second-order Newton-Einstein classical gravitational theory. On the observational side we discuss the degree to which the realm of validity of Newton's law of gravity can actually be extended to distances much larger than the solar system distance scales on which the law was originally established. On the theoretical side we identify some commonly accepted (but actually still open to question) assumptions which go into the formulation (...) of the standard second-order Einstein theory in the first place. In particular, we show that while the familiar second-order Poisson gravitational equation (and accordingly its second-order covariant Einstein generalization) may be sufficient to yield Newton's law of gravity they are not in fact necessary. The standard theory thus still awaits the identification of some principle which would then make it necessary too. We show that current observational information does not exclusively mandate the standard theory, and that the conformal invariant fourth-order theory of gravity considered recently by Mannheim and Kazanas is also able to meet the constraints of data, and in fact to do so without the need for any so far unobserved nonluminous or dark matter. (shrink)

Abstract:The concept of social progress I hope to rehabilitate will be local, far from locally complete, and permit only modest extensions; it will be pragmatic rather than teleological. In this way, it will hope to avoid treating the multiplicity of goods as if there were always the possibility of comparing them on a single scale, to abandon the idea of a final state toward which history is tending or should tend, and to substitute piecemeal accomplishments for utopian ends. Its emphasis (...) on local comparisons will allow it to forgo sweeping historical comparisons, those juxtaposing the “enlightened” with “lesser breeds without the law,” or the “ancients” with the “moderns.” A restrained pragmatic concept of social progress honors the insights of critics of the notion of social progress, seeing them as questioning alleged presuppositions that can be given up. (shrink)

W.V.O.Quine’s doctrine of referential inscrutability (RI) is the thesis that, first, linguistic reference must always be determined relative to an interpretation of the discourse and, second, that the empirical evidence always underdetermines our choice of interpretation--at least in principle. Although this thesis is a central result of Quine’s theory of language, it was long unclear just how much force RI actually carried. At best, Quine’s discussions provided localized examples of RI (e.g., ‘gavagai’), supplemented merely by arguments for the (in principle) (...) constructability of more general referentially divergent manuals. In defense of Quine, Gerald Massey provides a method for generating large-scale referentially divergent manuals for a complex language. I argue that, while Massey’s rival manuals do meet Quine’s translational criteria, they are demonstrably inferior to their commonsensical “homophonic” competitor. This result provides a clear indication of seminal deficiencies in Quine’s behaviorial approach to the theory of language. Next I argue that Quine’s acceptance of standard assumptions about the nature of perception strongly influences the shape of his semantical theory. Finally, I suggest how an alternative to the standard account of perception might provide grounds for a more adequate understanding of language. (shrink)

Research on temporal comparison has shown that people dissociate themselves from their past to attain a positive self view. Social comparison research has demonstrated that the distinctness of contextually activated information determines whether a recalled self exerts assimilation or contrast effects on the current self. However, hardly any study addressed individual differences. Also, very little is known about whether the ease or difficulty to date past events and experiences influences current self-judgments. We present a new scale capturing the degree of (...) the current self time extension. Three studies support the notion that temporal self-extension determines how past selves are accessed and processed, regarding both the abstractness with which self-knowledge is retrieved and the experienced temporal distance to the past. These findings have important implications for temporal as well as social comparison processes. (shrink)

Peirce’s cosmogonic philosophy of Nature represents a radical rethinking of the idea of emergence, replacing the traditional metaphysics of mechanism that was dominant within the science of the day with the idea of a chance world as the base or grounding condition of the general order of Nature. The result is a novel and potentially revolutionary account of emergent evolution that sees both the conditions of mechanism and generalized conformity to law as emergent conditions that come into being through evolutionary (...) processes operating at a cosmological scale. By grounding evolutionary cosmogony in the idea of chance Peirce’s philosophy of Nature represents a radical and important departure from much of the emergentist tradition. Most importantly, it offers the groundwork for a general theory of emergence that would see emergent phenomena as generally predictable and explicable part of the general order of Nature as such. (shrink)

The magnificence of Augustan Rome is the indispensable setting for Ovid the urbane love poet, rusticitas is the one unforgivable sin. Yet in Ovid's perpetuum carmen cities are for the most part invisible, at best incidental backdrops; the countryside, present in many vividly drawn landscapes, constantly thrusts itself on our attention, a place where mysterious powers menace the individual's identity. This neglect of the city makes a striking, and deliberate, contrast with the Aeneid, a ktistic epic whose meaning is governed (...) by constant reference forward to the ‘altae moenia Romae’. Ovid, whose main epic time-scale does include the foundation of Rome, devotes five words to the making of those walls. The one major exception to this indifference to the central theme of Virgilian epic is the Theban episode in Metamorphoses 3.1–4.603. The story of Cadmus and his family forms a self-contained unit within the flux of Ovid's epic of transformation. It tells of a ktisis that goes wrong: Cadmus obeys Apollo's injunction to found a city , but in the end the exile who had founded a new home is driven into a second exile: ‘exit | conditor urbe sua’. (shrink)

We live in a complex world, made more complex for us by the difficulty of distinguishing between our cultural expectations for how things work and the physical systems we interact with. The environmental systems of nature and the economy are often hard to recognize and constantly change, having behaviors independent of what people think about them. So our rules for systems we come to trust can become highly misleading without notice. That seems to have happened to us, evident in how (...) people still project models of economic growth into the future, and already missing the turning point of timely response to erupting strains, fairly clearly around a century ago. That makes it valuable to know how the laws of physics provide some simple boundary conditions for responding to change in environmental systems, and knowing when you should.Learning to identify natural systems change and how to respond starts with learning to distinguish between physical systems, as one of our independent realities, and our worlds of information and belief as another. Once you can distinguish our information from its physical subjects you can compare the difference, and plan for change. Telling them apart can be a challenge, however, requiring attention to their distinctly different kinds of energy use, organization and natural limits. Environmental systems often change with their actively learning parts too, for another reason watching them change is more important than having theories of how they worked in the past.A useful way to find and track change in physical systems is found in how the conservation laws require energy flow and energy transfer processes to begin and end. They need a continuity that can be identified in recorded measures, made useful by raising key questions about irreversible changes precipitated by regular changes in scale. It builds a new bridge of methodology between theoretical and physical systems, introducing a new kind of empirical research. (shrink)

Portraying psychological process as extended over time in multiply overlapping scales is a conceptual advance that can be understood as analogous to our understanding of spatial relationships. There may be a residual contradiction, however, when Rachlin invokes in ways that seem to imply earlier conceptions. The roles of superimposed or conditionally related stimuli also remain to be addressed.

Many recent writers on democracy have lamented its decay and warned of its imminent death. We argue that the concerns are focused at three different levels of democracy. The most fundamental of these, celebrated by Tocqueville and by Dewey, recognizes the interactions and joint deliberations among citizens who seek sympathetic mutual engagement. Such engagement is increasingly rare in large-scale political life. In diagnosing and treating the problems, we recommend returning to the debate between Lippmann and Dewey, in which many of (...) the concerns now prominent were already voiced. This inspires the main work of the paper – the reconstruction of Dewey’s conception of democracy as a ‘mode of associated living’. We focus on the thesis that democracy is educative and explicate Dewey’s notion of growth, showing how democratic education contributes to three important functions: the capacity for sustaining oneself, the enrichment of individual experience, and the ability to enter into cooperative discussions with fellow citizens. Dewey’s conception of democratic education is directed at fostering particular virtues and, if citizens come to possess them, the need for Lippmann’s ‘omnicompetent individual’ vanishes. We conclude by suggesting that Dewey’s project of educating democratic character is pertinent for addressing the disaffection of our times. (shrink)

Behavioral immune system describes psychological mechanisms that detect cues to infectious pathogens in the immediate environment, trigger disease-relevant responses and facilitate behavioral avoidance/escape. BIS activation elicits a perceived vulnerability to disease which can result in conformity with social norms. However, a response to superficial cues can result in aversive responses to people that pose no actual threat, leading to an aversion to unfamiliar others, and likelihood of prejudice. Pathogen-neutralizing behaviors, therefore, have implications for social interaction as well as illness behaviors (...) and responses to health communications. In this study, we investigate how PVD influences conformity, attitudes to other people and to lockdown regulations through the lens of the Reinforcement Sensitivity Theory. RST describes personality in terms of biologically-driven approach and avoidance motivations which support personal goals. Participants from the United Kingdom public completed an RST personality questionnaire and then read either coronavirus morbidity-mortality statistics and current United Kingdom government lifestyle regulations, just the regulations, or no information at all. They all completed the Perceived Vulnerability to Disease scale to assess BIS-relevant Germ Aversion and Perceived Infectability, followed by questions measuring social conformity, warmth toward others and attitudes toward lockdown measures. Significantly lower PVD scores were observed in the no-information condition, with the other conditions showing no difference. In terms of RST, approach behaviors related to goal-drive persistence work alongside fear in explaining conformity to social norms. Reward related approach behaviors partially explained warmth toward others, indicating that social rewards gained through interaction continue to be strong drivers of behavior. We found no role for RST traits in attitudes toward lockdown. Overall, coronavirus-related behavior is not driven purely by fear, but also by social and/or protection goals regulated by approach motivation. This study presents new insights into public perceptions of coronavirus and government regulated lifestyle restrictions, helping to explain social behaviors in terms of biologically driven mechanisms. Such understanding is vital if we are to successfully motivate public behavior to constrain spread of the virus. (shrink)

This chapter contains sections titled: The Decision ‐ Theoretic Picture The Decision ‐ plus ‐ Deliberation Picture A Common Mistake References.

This article argues that universities have duties to negotiate contracts with the pharmaceutical industry that are favourable to the world’s poor, and to do more research into diseases which disproportionately strike the global poor. It is argued that these duties are related to human rights (in particular to a human right to health) and that they are therefore very weighty. Furthermore, these duties are in line with some of the most important things that Universities Allied for Essential Medicines (UAEM), a (...) worldwide group of students and academics, wants universities to do. A number of objections are discussed, among other things to do with safeguarding pharmaceutical innovation, and it is argued that the aforementioned duties should, as UAEM also advocates, often be combined with efforts on the part of universities to work towards more long-term, large-scale institutional arrangements to ensure access to and availability of essential medicines for the global poor. -/- . (shrink)

Around the world, agricultural landscapes are increasingly seen as “multi-functional” spaces, expected to deliver food supplies while improving rural livelihoods and protecting and restoring healthy ecosystems. To support this array of functions and benefits, governments and civil society in many regions are now promoting integrated farm- and landscape-scale management strategies, in lieu of fragmented management strategies. While rural producers are fundamental to achieving multi-functional landscapes, they are frequently viewed as targets of, or barriers to, landscape-oriented initiatives, rather than as leading (...) agents of change. In reality, however, rural producers in many areas have embraced elements of multi-functional land management. In this paper, we explore the role and recent evolution of producer movements in influencing multi-functional farm and landscape management. We explore these roles through six case studies, including a land reform movement in Brazil, indigenous territorial development in Bolivia, conservation agriculture associations in Canada, environmental cooperatives in the Netherlands, indigenous and biocultural heritage associations in Peru, and Landcare groups in the Philippines. These experiences suggest that producer movements are playing pivotal roles in supporting landscape multi-functionality, not only through agroecological farming practices but also through off-farm efforts to conserve ecosystems and support multi-stakeholder landscape planning. On the other hand, interests of producer movements are not always fully aligned with multi-functional landscape management approaches. The contribution of producer movements to multi-functional landscapes depends on these movements including farm and landscape stewardship in their values and goals, and having the political support and capacity to engage meaningfully in multi-stakeholder processes. (shrink)

Tremendous agricultural potential in Colombia has gone untapped for decades due to: i) civil strife and the criminal drug trade; ii) uncertain property rights; iii) inadequate infrastructure; iv) lack of innovation and technological development; v) lack of funding, vi) lack of investment; and vii) misallocation of resources within the sector. Proof of this is the relatively lower growth of the value of Colombia’s agriculture versus other countries in the region during the agricultural prices booms (FAO, 2015). This paper analyzes whether (...) Colombia’s weak agricultural performance was due to low productivity growth rather than input accumulation. Using econometric specifications, this paper finds that Colombia’s agricultural productivity grew on average between 0.8% and 1.3% annually from 1975 and 2013. This growth was mainly driven by livestock and poultry productivity, which grew between 1.6% and 2.2%, while crop productivity grew between 0% and 0.8%. Likewise, this paper finds biased technical and scale effects whenever the models are able to test their presence. In addition, it finds evidence that Colombia’s agricultural productivity growth was affected by changing economic circumstances. These results are significant for post-conflict rural investment because they provide information about the returns on future government investment options in the rural sector of Colombia. (shrink)

Measuring and assessing the different aspects of gambling behavior and its consequences is crucial for planning prevention, treatment, and understanding the development of at-risk and problem gambling. Studies indicate that instruments measuring problem gambling produce different results based on the characteristics of the population assessed. To accurately measure at-risk and problem gambling behavior, especially in a low-risk population, measures must cover a wider set of dimensions than the negative consequences already manifest. The Jonsson-Abbott Scale includes items that cover overconsumption, actions (...) that reinforce gambling behavior, and belief in gambling fallacies, based on a three-factor structure and has previously demonstrated good psychometric properties. However, there is a need to investigate how the instrument also functions in low-risk populations. This study aims to do so using both confirmatory factor and Rasch analysis; this research included 1,413 Swedish participants who endorsed at least one JAS item. The results replicated the previous three-factor solution and indicated that the instrument had good reliability. In addition, the results demonstrated that the three factors are independent, and the overall score per factor needs to be analyzed. In summary, the JAS appears suitable for use in low-risk populations to measure various aspects of gambling behavior. (shrink)

This article provides current Schwartz Values Survey (SVS) data from samples of business managers and professionals across 50 societies that are culturally and socioeconomically diverse. We report the society scores for SVS values dimensions for both individual- and societal-level analyses. At the individual-level, we report on the ten circumplex values sub-dimensions and two sets of values dimensions (collectivism and individualism; openness to change, conservation, self-enhancement, and self-transcendence). At the societal-level, we report on the values dimensions of embeddedness, hierarchy, mastery, affective (...) autonomy, intellectual autonomy, egalitarianism, and harmony. For each society, we report the Cronbach’s α statistics for each values dimension scale to assess their internal consistency (reliability) as well as report interrater agreement (IRA) analyses to assess the acceptability of using aggregated individual level values scores to represent country values. We also examined whether societal development level is related to systematic variation in the measurement and importance of values. Thus, the contributions of our evaluation of the SVS values dimensions are two-fold. First, we identify the SVS dimensions that have cross-culturally internally reliable structures and within-society agreement for business professionals. Second, we report the society cultural values scores developed from the twenty-first century data that can be used as macro-level predictors in multilevel and single-level international business research. (shrink)

Physical activity, and likely the motivation for it, varies throughout the day. The aim of this investigation was to create a short assessment (CRAVE: Cravings for Rest and Volitional Energy Expenditure) to measure motivation states (wants, desires, urges) for physical activity and sedentary behaviors. Five studies were conducted to develop and evaluate the construct validity and reliability of the scale, with 1,035 participants completing the scale a total of 1,697 times. In Study 1, 402 university students completed a questionnaire inquiring (...) about the want or desire to perform behaviors “at the present moment (right now).” Items related to physical activity (e.g., “move my body”) and sedentary behaviors (e.g., “do nothing active”). An exploratory structural equation model (ESEM) revealed that 10 items should be retained, loading onto two factors (5 each for Move and Rest). In Study 2, an independent sample (n= 444) confirmed these results and found that Move and Rest desires were associated with stage-of-change for exercise behavior. In Study 3, 127 community-residing participants completed the CRAVE at 6-month intervals over two years- two times each session. Across-session interclass correlations (ICC) for Move (ICC = 0.72–0.95) and Rest (ICC = 0.69–0.88) were higher than when they were measured across 24-months (Move: ICC = 0.53; Rest: ICC = 0.49), indicating wants/desires have state-like qualities. In Study 4, a maximal treadmill test was completed by 21 university students. The CRAVE was completed immediately pre and post. Move desires decreased 26% and Rest increased 74%. Changes in Move and Rest desires were moderately associated with changes in perceived physical fatigue and energy. In Study 5, 41 university students sat quietly during a 50-min lecture. They completed the CRAVE at 3 time points. Move increased 19.6% and Rest decreased 16.7%. Small correlations were detected between move and both perceived energy and tiredness, but not calmness or tension. In conclusion, the CRAVE scale has good psychometric properties. These data also support tenets of the WANT model of motivation states for movement and rest (Stults-Kolehmainen et al., 2020a). Future studies need to explore how desires to move/rest relate to dynamic changes in physical activity and sedentarism. (shrink)

The resurgence of tuberculosis in the United States is due, in part, to the dismantling of large-scale treatment systems that were a critical part of the disease control effort for the better part of the twentieth century. As the number of cases grows, clinicians, politicians, public health officials and community advocates have grappled with the difficult problem of building systems to care for infected people that are consonant with current knowledge and beliefs about quality care. As an example, the United (...) Hospital Fund’s 1992 report, The Tuberculosis Revival: Individual and Societal Obligations in a Time of AIDS, discussed policies to guarantee adequate treatment that protects patients’ civil rights, needs for special facilities for care of TB patients, and the special problems faced by infected prisoners. This thoughtful report highlighted many areas of social policy that require further examination. (shrink)

The resurgence of tuberculosis in the United States is due, in part, to the dismantling of large-scale treatment systems that were a critical part of the disease control effort for the better part of the twentieth century. As the number of cases grows, clinicians, politicians, public health officials and community advocates have grappled with the difficult problem of building systems to care for infected people that are consonant with current knowledge and beliefs about quality care. As an example, the United (...) Hospital Fund’s 1992 report, The Tuberculosis Revival: Individual and Societal Obligations in a Time of AIDS, discussed policies to guarantee adequate treatment that protects patients’ civil rights, needs for special facilities for care of TB patients, and the special problems faced by infected prisoners. This thoughtful report highlighted many areas of social policy that require further examination. (shrink)

Cancer is a complex disease, necessitating research on many different levels; at the subcellular level to identify genes, proteins and signaling pathways associated with the disease; at the cellular level to identify, for example, cell-cell adhesion and communication mechanisms; at the tissue level to investigate disruption of homeostasis and interaction with the tissue of origin or settlement of metastasis; and finally at the systems level to explore its global impact, e.g. through the mechanism of cachexia. Mathematical models have been proposed (...) to identify key mechanisms that underlie dynamics and events at every scale of interest, and increasing effort is now being paid to multi-scale models that bridge the different scales. With more biological data becoming available and with increased interdisciplinary efforts, theoretical models are rendering suitable tools to predict the origin and course of the disease. The ultimate aims of cancer models, however, are to enlighten our concept of the carcinogenesis process and to assist in the designing of treatment protocols that can reduce mortality and improve patient quality of life. Conventional treatment of cancer is surgery combined with radiotherapy or chemotherapy for localized tumors or systemic treatment of advanced cancers, respectively. Although radiation is widely used as treatment, most scheduling is based on empirical knowledge and less on the predictions of sophisticated growth dynamical models of treatment response. Part of the failure to translate modeling research to the clinic may stem from language barriers, exacerbated by often esoteric model renderings with inaccessible parameterization. Here we discuss some ideas for combining tractable dynamical tumor growth models with radiation response models using biologically accessible parameters to provide a more intuitive and exploitable framework for understanding the complexity of radiotherapy treatment and failure. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Scale Theory: A Nondisciplinary Inquiry by Joshua DiCaglioS. Scott GrahamScale Theory: A Nondisciplinary Inquiry. By Joshua DiCaglio. Minneapolis: University of Minnesota Press, 2021. 349 pp. Paperback: $30.00. ISBN: 978-1-5179-1207-9.Scale Theory embodies its title in every possible way. It offers both a deep dive into and a 10,000-foot view of scale, scalar thinking, and the role of scale in scientific inquiry. The subtitle, A Nondisciplinary Inquiry, is no less (...) apt. Author Joshua DiCaglio blends insights from rhetoric, philosophy, literary studies, and mysticism to create a novel account of scalar thinking. In so doing, he weaves together detailed thought experiments, the work of Gregory Bateson, and Philip K. Dick's account of an extraterrestrial communication he received while under the influence of anesthesia. Provocatively, Scale Theory treats these diverse intellectual resources as coequal contributors to an emerging theory of scale and scalar thinking. Within this nondisciplinary framework, the book is devoted to advancing two primary theses: (1) Notions of scale are undertheorized in science studies and related strands of new materialisms; and (2) Proper attention to questions of scale within these theoretical traditions should prompt a more thoughtful reconsideration of the merits of mystic holism. Ultimately, Scale Theory makes a compelling case for the first thesis and advances inquiry usefully in this area. With respect to the second thesis, DiCaglio refers to a certain academic "allergy" to holism (99), and I must confess I share this allergy. That said, I assume readers already predisposed favorably toward mystic holism are likely to find Scale Theory's attention to the second thesis thoughtful and engaging.Scale Theory is organized into three distinct parts. Part 1, "Algorithms for a Theory of Scale," presents three interrelated thought experiments that call upon readers to imagine themselves at various distances and vantage points with respect to several objects of interest. Part 1 is stylistically [End Page 388] Wittgensteinian. Like the Tractatus-Logico Philosophicus (Wittgenstein 2013) or Latour's "Irreductions," (1993), the thought experiments unfold as a series of numbered and nested propositions, each postulating or interrogating an emerging concept in DiCaglio's theory of scale. Part 2, "Configurations for a Theory of Scale," returns the reader to more familiar styles of prose, providing a sort of review of the relevant literature and its relationship to the insights of the thought experiments. Finally, part 3, "Rhetorical Technologies for a Theory of Scale," reflects on the twin marginalizations of rhetoric and mysticism in mainstream Western academia and argues for a new embrace of disembodied inquiry.The aforementioned thought experiments of part 1 outline DiCaglio's theories of scale, scalar thinking, and scalar analysis. The discussion makes extensive use of visual and cinematic metaphors to aid the reader's consideration of scalar questions. Ultimately, DiCaglio posits that scale is a function of the relationship between the "'being' of phenomena" and "the one who is measuring" (8). He argues, therefore, that "scale functions at a level above ontology and epistemology: scale is a means of orienting yourself both to experience and the being of things" (8). In making this argument, Scale Theory reflects on a range of scientific practices that require gradients of scale. Microscopy, telescopy, and simulations all provide scientists with tools to escape the mundane scales of embodied human experience. DiCaglio argues that "science must always find itself grouping things together, speaking of species, types, systems, and so on which exist on a different logical type than the individual encounters that make up these groups" (41). The taxonomic activities of scientific practice require shifts in scale to account for kingdoms, phyla, orders, genera, species, and all manner of nonbiological analogs.Within this framework, scale functions as a sort of meta-ontology that allows objects to be provisionally identified and delineated. Echoing Bateson, DiCaglio argues thatIn order for any thing to be said to exist whatsoever, a differential must exist out of which a difference can be discerned. Every differential occurs on some scale at which a fluctuation or movement is able to make a difference. If one goes to a smaller scale, any given differential is no longer able to be used to register a difference.(51... (shrink)

Introductory Chapter to the _Cambridge Handbook of Situated Cognition_ (CUP, 2009).

In the monograph under review, a revised version of a dissertation submitted at the University of Konstanz in 2019, Polcar sets out to provide a full-scale commentary on a single letter of Jerome’s correspondence such as will be familiar to those who have read the work of Scourfield, Adkin, and Cain. The letter under investigation, epistula 79, is addressed to the newly widowed Salvina, containing both consolation for the loss of her husband, Nebridius, and exhortation to chaste widowhood. After a (...) brief introduction to Jerome and the letter’s place in the ancient epistolographic tradition (pp. 11–19) and a survey of the edition and the manuscripts consulted (21–24), there follows a Latin text with a facing translation (pp. 24–45). (shrink)

This article rewrites the history of the tomb of Philip the Bold made for the Chartreuse de Champmol in Dijon, through a close reading and re-transcription of the entire archival record, including some previously unknown documents, paying careful attention to what their terminology and chronology reveal about time, cost, materials and process; it analyses the scale of the project, and in particular the acquisition and working of materials: limestone from Tonnerre, ‘alabaster’ as spolia from Autun, black marble from Dinant, (...) white marble, presumably from Italy, via Paris, alabaster from Grenoble and a pinkish limestone from Resne, near Dijon. By reconsidering this record, along with the physical and visual evidence of the existing monument, it argues that there was not one but two tombs made for Philip the Bold: the first was completed by Jean de Marville and then rejected by Philip, and perhaps also by the Carthusians; the second, that we have today, was started again from scratch in the early 1390s by Claus Sluter, in collaboration, possibly, with Jacques de Baerze. The story of how these two tombs were planned, worked on, adapted or restarted, along with what Marville’s abandoned project may have looked like, and what may have become of its constituent parts, is woven into the narrative of Philip’s political and religious ambitions, the role of his wife Margaret of Flanders, and of the construction and decoration of the Chartreuse de Champmol itself. (shrink)

In Working Virtue: Virtue Ethics and Contemporary Moral Problems, leading figures in the fields of virtue ethics and ethics come together to present the first ...

Husserlian phenomenology, as the study of conscious experience, has often been accused of solipsism. Husserl’s method, it is argued, does not have the resources to provide an account of consciousness of other minds. This chapter will address this issue by providing a brief overview of the multiple angles from which Husserl approached the theme of intersubjectivity, with specific focus on the details of his account of the concrete interpersonal encounter – “empathy.” Husserl understood empathy as a direct, quasi-perceptual form of (...) intentionality through which the sense of the Other is constituted. Furthermore, his account of empathy is holistically integrated with his overall theory of intersubjectivity, including his discussions of the objectivity of nature, and the social, historical, and communal aspects of subjectivity. Husserl’s theory of empathy continues to cast a long shadow, influencing both the analytic and continental approaches to the problem of other minds, as well as contemporary account of social cognition in the cognitive sciences. (shrink)

_Time_ offers a comprehensive history of the philosophy of time in western philosophy from the Greeks through to the twentieth century. In the first half of the book, Philip Turetzky explores theories in ancient and modern philosophy chronologically: from Aristotle to Nietzsche. In the latter half, Turetzky describes the philosophy of time in three twentieth-century philosophical traditions: * analytic philosophy including philosophers such as McTaggart and Mellor * phenomenology Husserl and Heidegger * a distaff tradition which Turetzky identifies as (...) including Bergson and Deleuze. (shrink)

This article draws on the antebellum political thought of Black abolitionists Frederick Douglass and Martin Delany in critically assessing the efficacy of reasonableness in advancing the aims of emancipatory politics in political discourse. I argue, through a reading of Douglass and Delany, that comporting oneself reasonably in the face of oppressive ideology can be counterproductive, if one’s aim is to undermine such ideology and the institutions it supports. Douglass and Delany, I argue, also provide us with a framework for evaluating (...) alternative discursive strategies we might wish to employ in light of the limited value of reasonableness for emancipatory politics. (shrink)

Four of the commentaries criticised my claim that assisted suicide for the terminally ill is discriminatory. 1 They were united in this judgement roughly because they insisted that assisted suicide is in fact a benefit and not a harm. I concede that if it is a benefit, then there is no way in which the terminally ill can be disadvantaged by it and hence no way it can be an instance of discrimination. I pointed out in the article that this (...) issue is controversial and could not be settled in my article, nor can it be settled in this brief response. Assisted suicide harms the terminally ill in several ways. First, it harms the people who do not adopt it by forcing them to defend their continued existence. Second, it harms many of the people who adopt it in so far as they are deprived of a life... (shrink)

We provide empirical examples to conceptually clarify some items on Firestone & Scholl’s (F&S’s) checklist, and to explain perceptual effects from an attentional and memory perspective. We also note that action and embodied cognition studies seem to be most susceptible to misattributing attentional and memory effects as perceptual, and identify four characteristics unique to action studies and possibly responsible for misattributions.

Political ecology has developed as an academic discipline in reaction to the increased concern of nations and individuals about humanity's adverse impact on the environment and the ways international bodies have moved to counter this impact. This new text draws together international experts at the cutting edge of this new field to focus on real world examples of problems and the tension between developed and developing states.

This paper addresses the problem of the strategies and theories of democratic participation in Nigeria that breed institutional marginality and bad governance due to shortfalls in pursuing the values of justice and empowerment as core democratic characteristics. The same democratic principles such as voting, parliament, constitution, judiciary, that are suggestive of gains such as responsible use, and peaceful transfer of power may not have translated fully into sociopolitical empowerment for responsibility and representation in evolving democratic practice in Nigeria due to (...) problems of agency and political ideology. Democratic theorizing and participation in Nigeria has defied orthodox presuppositions seen in the disrespect for basic rights and the disregard for the rule of law in democracy that allow for fair play within and among the elites and political grassroots. Thus this study investigates the Nigerian predicament as a model or case study, raising questions about the reasons for the systematic disempowerment of groups. (shrink)

The questions -- The purpose of morality and law -- The past and the future -- What is religion? -- What is the rule of law? -- The families of religion : western religions -- The families of religion : eastern religions -- The families of law -- A brief tour of secular law -- Money, banks and corporations -- Secularisation and religious decline -- Reasons for the decline of religiosity -- Secularisation of government -- The rise of the lawyers (...) -- Who rules the world : lawyers or economists? -- What is wrong with the law? -- Scientific progress and the law -- A way of living -- A billion years from now. (shrink)

The _Platform Sutra_ records the teachings of Hui-neng, the Sixth Patriarch, who is revered as one of the two great figures in the founding of Ch'an (Zen) Buddhism. This translation is the definitive English version of the eighth-century Ch'an classic. Phillip B. Yampolsky has based his translation on the Tun-huang manuscript, the earliest extant version of the work. A critical edition of the Chinese text is given at the end of the volume. Dr. Yampolsky also furnishes a lengthy and detailed (...) historical introduction which contains much information hitherto unavailable even to scholars, and provides the context essential to an understanding of Hui-neng's work. He gives an account of the history and legends of Ch'an Buddhism, with particular attention to the traditions associated with Hui-neng, quoting or summarizing the most important narratives. He then discusses the various texts of the _Platform Sutra_, and analyzes its contents. (shrink)

The actualism/possibilism debate in ethics concerns the relationship between an agent’s free actions and her moral obligations. The actualist affirms, while the possibilist denies, that facts about what agents would freely do in certain circumstances partly determines that agent’s moral obligations. This paper assesses the plausibility of actualism and possibilism in light of desiderata about accounts of blameworthiness. This paper first argues that actualism cannot straightforwardly accommodate certain very plausible desiderata before offering a few independent solutions on behalf of the (...) actualist. This paper then argues that, contrary to initial appearances, possibilism is subject to its own comparably troubling blameworthiness problem. (shrink)