Results for 'Shane McCarthy'

981 found
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  1.  44
    Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.Vladimir Vacic, Shane McCarthy, Dheeraj Malhotra, Fiona Murray, Hsun-Hua Chou, Aine Peoples, Vladimir Makarov, Seungtai Yoon, Abhishek Bhandari, Roser Corominas, Lilia M. Iakoucheva, Olga Krastoshevsky, Verena Krause, Verónica Larach-Walters, David K. Welsh, David Craig, John R. Kelsoe, Elliot S. Gershon, Suzanne M. Leal, Marie Dell Aquila, Derek W. Morris, Michael Gill, Aiden Corvin, Paul A. Insel, Jon McClellan, Mary-Claire King, Maria Karayiorgou, Deborah L. Levy, Lynn E. DeLisi & Jonathan Sebat - unknown
    Rare copy number variants have a prominent role in the aetiology of schizophrenia and other neuropsychiatric disorders. Substantial risk for schizophrenia is conferred by large CNVs at several loci, including microdeletions at 1q21.1, 3q29, 15q13.3 and 22q11.2 and microduplication at 16p11.2. However, these CNVs collectively account for a small fraction of cases, and the relevant genes and neurobiological mechanisms are not well understood. Here we performed a large two-stage genome-wide scan of rare CNVs and report the significant association of copy (...)
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  2.  19
    A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay.Santhosh Girirajan, Jill A. Rosenfeld, Gregory M. Cooper, Francesca Antonacci, Priscillia Siswara, Andy Itsara, Laura Vives, Tom Walsh, Shane E. McCarthy, Carl Baker, Heather C. Mefford, Jeffrey M. Kidd, Sharon R. Browning, Brian L. Browning, Diane E. Dickel, Deborah L. Levy, Blake C. Ballif, Kathryn Platky, Darren M. Farber, Gordon C. Gowans, Jessica J. Wetherbee, Alexander Asamoah, David D. Weaver, Paul R. Mark, Jennifer Dickerson, Bhuwan P. Garg, Sara A. Ellingwood, Rosemarie Smith, Valerie C. Banks, Wendy Smith, Marie T. McDonald, Joe J. Hoo, Beatrice N. French, Cindy Hudson, John P. Johnson, Jillian R. Ozmore, John B. Moeschler, Urvashi Surti, Luis F. Escobar, Dima El-Khechen, Jerome L. Gorski, Jennifer Kussmann, Bonnie Salbert, Yves Lacassie, Alisha Biser, Donna M. McDonald-McGinn, Elaine H. Zackai, Matthew A. Deardorff, Tamim H. Shaikh, Eric Haan, Kathryn L. Friend, Marco Fichera, Corrado Romano, Jozef Gécz, Lynn E. DeLisi, Jonathan Sebat, Mary-Claire King, Lisa G. Shaffer & Eic - unknown
    We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...)
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  3. A More Practical Pedagogical Ideal: Searching for a Criterion of Deweyan Growth. [REVIEW]Shane Jesse Ralston - 2011 - Educational Theory 61 (3):351-364.
    When Dewey scholars and educational theorists appeal to the value of educative growth, what exactly do they mean? Is an individual's growth contingent on receiving a formal education? Is growth too abstract a goal for educators to pursue? Richard Rorty contended that the request for a “criterion of growth” is a mistake made by John Dewey's “conservative critics,” for it unnecessarily restricts the future “down to the size of the present.” Nonetheless, educational practitioners inspired by Dewey's educational writings may ask (...)
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  4.  16
    Understanding and Resolving Failures in Human-Robot Interaction: Literature Review and Model Development.Shanee Honig & Tal Oron-Gilad - 2018 - Frontiers in Psychology 9.
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  5. Universal intelligence: A definition of machine intelligence.Shane Legg & Marcus Hutter - 2007 - Minds and Machines 17 (4):391-444.
    A fundamental problem in artificial intelligence is that nobody really knows what intelligence is. The problem is especially acute when we need to consider artificial systems which are significantly different to humans. In this paper we approach this problem in the following way: we take a number of well known informal definitions of human intelligence that have been given by experts, and extract their essential features. These are then mathematically formalised to produce a general measure of intelligence for arbitrary machines. (...)
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  6.  20
    Modernism and nihilism.Shane Weller - 2011 - New York: Palgrave-Macmillan.
    At the heart of some of the most influential strands of philosophical, political, and aesthetic modernism lies the conviction that modernity is fundamentally nihilistic. This book offers a wide-ranging critical history of the concept of nihilism from its origins in French Revolutionary discourse to its place in recent theorizations of the postmodern. Key moments in that history include the concept's appropriation by political activists in mid-nineteenth-century Russia, by Nietzsche in the 1880s, by the European avant-garde and 'high' modernists in the (...)
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  7.  68
    What is Working, What is Not, and What We Need to Know: a Meta-Analytic Review of Business Ethics Instruction.Shane Connelly, Michael D. Mumford, Logan M. Steele, Tyler J. Mulhearn, Logan L. Watts & Kelsey E. Medeiros - 2017 - Journal of Academic Ethics 15 (3):245-275.
    Requirements for business ethics education and organizational ethics trainings mark an important step in encouraging ethical behavior among business students and professionals. However, the lack of specificity in these guidelines as to how, what, and where business ethics should be taught has led to stark differences in approaches and content. The present effort uses meta-analytic procedures to examine the effectiveness of current approaches across organizational ethics trainings and business school courses. to provide practical suggestions for business ethics interventions and research. (...)
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  8.  59
    A managerial in-basket study of the impact of trait emotions on ethical choice.Shane Connelly, Whitney Helton-Fauth & Michael D. Mumford - 2004 - Journal of Business Ethics 51 (3):245-267.
    This paper explores the relationship of various trait emotions to the ethical choices of 189 college students who completed a managerial decision-making task as part of an in-basket exercise in a laboratory setting. Prior research regarding emotion influences on ethical decision-making and linkages between emotions and cognition informed hypotheses about how different types of emotions impact ethical choices. Findings supported our expectations that positive and negative emotions classified as active would be more strongly related to interpersonally-directed ethical choices than to (...)
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  9. Out of our heads: Addiction and psychiatric externalism.Shane Glackin, Tom Roberts & Joel Krueger - 2021 - Behavioral Brain Research 398:1-8.
    In addiction, apparently causally significant phenomena occur at a huge number of levels; addiction is affected by biomedical, neurological, pharmacological, clinical, social, and politico-legal factors, among many others. In such a complex, multifaceted field of inquiry, it seems very unlikely that all the many layers of explanation will prove amenable to any simple or straightforward, reductive analysis; if we are to unify the many different sciences of addiction while respecting their causal autonomy, then, what we are likely to need is (...)
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  10. Supported Decision-Making: Non-Domination Rather than Mental Prosthesis.Allison M. McCarthy & Dana Howard - 2023 - American Journal of Bioethics Neuroscience 14 (3):227-237.
    Recently, bioethicists and the UNCRPD have advocated for supported medical decision-making on behalf of patients with intellectual disabilities. But what does supported decision-making really entail? One compelling framework is Anita Silvers and Leslie Francis’ mental prosthesis account, which envisions supported decision-making as a process in which trustees act as mere appendages for the patient’s will; the trustee provides the cognitive tools the patient requires to realize her conception of her own good. We argue that supported decision-making would be better understood (...)
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  11.  11
    Literature, philosophy, nihilism: the uncanniest of guests.Shane Weller - 2008 - New York: Palgrave-Macmillan.
    Absolute devaluation : Friedrich Nietzsche -- Homelessness : Martin Heidegger -- Fatal positivities : Theodor Adorno -- The naive calculation of the negative : Maurice Blanchot -- Bad violence : Jacques Derrida -- The fracture : Giorgio Agamben -- Distortions, or, Nihilism against itself : Gianni Vattimo -- The denial of (Greek) thought : Alain Badiou.
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  12. Rather than nothing' : Derrida, literature, and the resistance of Nihilism.Shane Weller - 2007 - In Simon Wortham & Allison Weiner (eds.), Encountering Derrida: legacies and futures of deconstruction. New York: Continuum.
  13. A Collection of Definitions of Intelligence.Shane Legg & Marcus Hutter - 2007 - :1–12.
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  14.  49
    Formal Logic: Its Scope and Limits.Timothy McCarthy - 1967 - Journal of Symbolic Logic 49 (4):1408-1409.
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  15.  13
    Moral vision: seeing the world with love and justice.David Matzko McCarthy - 2018 - Grand Rapids, Michigan: William B. Eerdmans Publishing Company.
    In this new textbook two Catholic ethicists with extensive teaching experience present a moral theology based on vision. David Matzko McCarthy and James M. Donohue draw widely from the Western philosophical tradition while integrating biblical and theological themes in order to explore such fundamental questions as What is good? The fourteen chapters in Moral Vision are short and thematic. Substantive study questions engage with primary texts and encourage students to apply theory to everyday life and common human experiences. The (...)
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  16.  16
    Subjunctive Reasoning.Timothy McCarthy - 1981 - Journal of Symbolic Logic 46 (1):170-173.
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  17. The Infectious Disease Ontology in the Age of COVID-19.Shane Babcock, Lindsay G. Cowell, John Beverley & Barry Smith - 2021 - Journal of Biomedical Semantics 12 (13).
    The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health. IDO Core is designed to be a disease and pathogen neutral ontology, covering just those types of entities and relations that are relevant to infectious diseases generally. IDO Core is then extended by a collection of ontology modules focusing on specific diseases and pathogens. In this paper we (...)
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  18.  35
    The Development of Diderot's "Salons" and the Shifting Boundary of Representational Language.Shane Agin - 2007 - Diderot Studies 30:11 - 29.
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  19.  10
    Negative Mythology.Shane Chalmers - 2020 - Law and Critique 31 (1):59-72.
    Can mythology be a form of critical theory in the service of right? From the standpoint of an Enlightenment tradition, the answer is no. Mythology is characterised by irrationality, and works to mystify reality, whilst critical theory is set against the irrational, its entire force directed at demystifying reality. In a post-Enlightenment tradition, reason, including critical reason, may take mythological form—indeed, there is identity as much as non-identity between the two forms, a mimetic relationship in which the rational cannot be (...)
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  20.  60
    Two Models of Moral Judgment.Shane Bretz & Ron Sun - 2018 - Cognitive Science 42 (S1):4-37.
    This paper compares two theories and their two corresponding computational models of human moral judgment. In order to better address psychological realism and generality of theories of moral judgment, more detailed and more psychologically nuanced models are needed. In particular, a motivationally based theory of moral judgment is developed in this paper that provides a more accurate account of human moral judgment than an existing emotion-reason conflict theory. Simulations based on the theory capture and explain a range of relevant human (...)
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  21.  42
    An evaluation of early and late stage attentional processing of positive and negative information in dysphoria.Matthew S. Shane & Jordan B. Peterson - 2007 - Cognition and Emotion 21 (4):789-815.
  22. Why paraphrase nihilism fails.Shane Maxwell Wilkins - 2016 - Synthese 193 (8):2619--2632.
    Nihilists cannot square their position with common sense simply by paraphrasing away apparent ontological commitments in ordinary language. I argue for this claim by analogy. Paraphrase atheism says there is no God, but tries to square the truth of atheism with ordinary religious sentences by paraphrasing away apparent ontological commitments. Obviously, paraphrase does not reconcile atheism with ordinary language about God. I discuss two different reasons that paraphrase can fail and suggest that both reasons afflict paraphrase nihilism. Hence, paraphrase nihilism (...)
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  23.  73
    The current link between management behavior and ethical philosophy.Shane R. Premeaux - 2004 - Journal of Business Ethics 51 (3):269-278.
    The current linkages between ethical theory and management behavior are investigated. The vignettes used in this investigation represent ethical dilemmas in the areas of coercion and control, conflict of interest, physical environment, and personal integrity. Overall, even with heightened ethical awareness the link between ethical philosophy and management behavior remains similar to that of the early 1990s. Generally, practitioners still rely heavily on the utilitarian ethical philosophy when making business decisions. However, more managers are now likely to select ethically appropriate (...)
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  24.  27
    Guidelines to Prevent Malevolent Use of Biomedical Research.Shane K. Green, Sara Taub, Karine Morin & Daniel Higginson - 2006 - Cambridge Quarterly of Healthcare Ethics 15 (4):432-439.
    In February 1975, a group of leading scientists, physicians, and policymakers convened at Asilomar, California, to consider the safety of proceeding with recombinant DNA research. The excitement generated by the promise of this new technology was counterbalanced by concerns regarding dangers that might arise from it, including the potential for accidental release of genetically modified organisms into the environment. Guidelines developed at the conference to direct future research endeavors had several consequences. They permitted research to resume, bringing to an end (...)
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  25.  16
    Toward a Mediating Understanding of Tongues: A Historical and Exegetical Examination of Early Literature.Shane M. Kraeger - 2010 - Eleutheria: A Graduate Student Journal 1 (1):5.
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  26.  6
    Altruism and prosocial behavior in groups.Shane R. Thye & Edward J. Lawler (eds.) - 2009 - United Kingdom: Emerald.
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  27. Anarchism and existentialism.Shane Wahl - 2017 - In Nathan J. Jun (ed.), Brill's Companion to Anarchism and Philosophy. Leiden: Brill.
  28.  26
    Overconfidently underthinking: narcissism negatively predicts cognitive reflection.Shane Littrell, Jonathan Fugelsang & Evan F. Risko - 2019 - Thinking and Reasoning 26 (3):352-380.
    There exists a large body of work examining individual differences in the propensity to engage in reflective thinking processes. However, there is a distinct lack of empirical research examining th...
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  29.  19
    The Contribution of Confucius to Virtue Epistemology.Shane Ryan & Chienkuo Mi - 2018 - In Masaharu Mizumoto, Stephen P. Stich & Eric S. McCready (eds.), Epistemology for the rest of the world. Oxford University Press. pp. 65-76.
    Scholars have typically regarded Confucius as an ethical thinker broadly construed and not as an epistemological thinker. This chapter seeks to overturn that view and, in doing so, has three basic goals. The first goal is to make the case that Confucian thought is of epistemological significance. Goal two is to locate the significance of Confucian thought within epistemology while accounting for the past overlooking of this significance. The third goal is to show that Confucian thought is not only of (...)
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  30.  13
    Identity Politics: Lesbian Feminism and the Limits of Community.Shane Phelan - 1991 - Temple University Press.
    "Lesbian feminism began and has fueled itself with the rejection of liberalism.... In this rejection, lesbian feminists were not alone. They were joined by the New Left, by many blacks in the civil rights movement, by male academic theorists.... What all these groups shared was an intense awareness of the ways in which liberalism fails to account for the social reality of the world, through a reliance upon law and legal structure to define membership, through individualism, through its basis in (...)
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  31.  12
    Dolphin natures, human virtues: MacIntyre and ethical naturalism.Shane Nicholas Glackin - 2008 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 39 (3):292-297.
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  32. Questioning Technology's Role in Environmental Ethics: Weak Anthropocentrism Revisited.Shane Epting - 2010 - Interdisciplinary Environmental Review 11 (1):18-26.
    Environmental ethics has mostly been practiced separately from philosophy of technology, with few exceptions. However, forward thinking suggests that environmental ethics must become more interdisciplinary when we consider that almost everything affects the environment. Most notably,technology has had a huge impact on the natural realm. In the following discussion, the notions of synthesising philosophy of technology and environmental ethics are explored with a focus on research, development, and policy.
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  33.  8
    Getting Specific: Postmodern Lesbian Politics.Shane Phelan - 1994 - U of Minnesota Press.
    Phelan examines lesbian political theory and points out the pitfalls of a lesbian feminism that ignores the specificities of race. As she searches for a democratic identity politics, she explores the possibilities for lesbian community and for alliances with other groups, as well as the political goals of lesbian action.
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  34.  71
    The Link Between Management Behavior and Ethical Philosophy in the Wake of the Enron Convictions.Shane Premeaux - 2009 - Journal of Business Ethics 85 (1):13-25.
    The current linkages between ethical theory and management behavior are investigated in the wake of the much-publicized convictions of Enron executives. The vignettes used in this investigation represent ethical dilemmas in the areas of coercion and control, conflict of interest, physical environment, and personal integrity. Since 2003, and after the successful prosecution of Enron executives, the link between ethical philosophy and management behavior has shifted somewhat dramatically. There has been a significant change in the rational basis for managerial decision making. (...)
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  35.  22
    State boredom results in optimistic perception of risk and increased risk-taking.Shane W. Bench, Jac’lyn Bera & Jaylee Cox - 2021 - Cognition and Emotion 35 (4):649-663.
    Boredom is a frequently experienced and unpleasant state (Bench & Lench, 2019; Danckert et al., 2018; Eastwood et al., 2012) that people are experiencing more frequently (Weybright et al., 2020). W...
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  36. Just Silence in Plato’s Clitophon.Shane Gassaway - 2019 - Polis 36 (2):266-288.
    Plato’s Clitophon presents a confrontation between two alternative views of justice, one conventional and the other philosophical – and of Clitophon’s inability to move from the one to the other due to his confusion over the relationship between knowledge and virtue and his misconception of the path from ignorance to knowledge, which probably results from his ambition. The nature of this confusion is such that Clitophon can only overcome it by abandoning his submissive stance toward the authority of Socrates, which (...)
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  37.  15
    Interpreting excess: Jean-Luc Marion, saturated phenomena, and hermeneutics.Shane Mackinlay - 2010 - New York: Fordham University Press.
    Introduction -- Marion's claims -- The hermeneutic structure of phenomenality -- The theory of saturated phenomena -- Events -- Dazzling idols and paintings -- Flesh as absolute -- The face as irregardable icon -- Revelation : the phenomenon of God's appearing -- Conclusion: Revising the phenomenology of givenness.
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  38.  20
    Pro-Life or Pro-Choice.Shane Andre - 1986 - Social Theory and Practice 12 (2):223-240.
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  39.  18
    Hobbesian Applied Ethics and Public Policy.Shane D. Courtland (ed.) - 2017 - New York: Routledge.
    Most philosophers and political scientists readily admit that Thomas Hobbes is a significant figure in the history of political thought. His theory was, arguably, one of the first to provide a justification for political legitimacy from the perspective of each individual subject. What has been largely missing in the literature, however, is the application of Hobbesian theory to a variety of current issues in both public policy and applied ethics. The essays in this volume, written by some of the top (...)
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  40. .Daniel Kahneman & Shane Frederick - 2002 - Cambridge University Press.
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  41.  13
    The Morality of Urban Mobility: Technology and Philosophy of the City.Shane Epting - 2021 - Rowman & Littlefield Publishers.
    Shane Epting illustrates that the problem of “moral prioritization” rests at the heart of problems with city transportation systems. To overcome such challenges, he develops a multitiered assessment system that shows how to evaluate complicated affairs in urban mobility.
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  42.  52
    An attempt at a general solution to the problem of deviant causal chains.Shane Ward - 2024 - Philosophy and Phenomenological Research 108 (2):374-395.
    Deviant causal chain problems arise in many settings. The most famous instance of the problem is the Gettier problem, but the problem also arises in the philosophy of action and perception. Usually, attempts to tackle these problems try to solve them individually. This paper takes a different approach: I propose a general solution to the problem. I begin by providing a solution to the deviant causal chain problem for skillful performance, and I argue that the solution can be extended to (...)
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  43.  42
    A pluralist view of nursing ethics.Joan McCarthy - 2006 - Nursing Philosophy 7 (3):157-164.
    This paper makes the case for a pluralist, contextualist view of nursing ethics. In defending this view, I briefly outline two current perspectives of nursing ethics – the Traditional View and the Theory View. I argue that the Traditional View, which casts nursing ethics as a subcategory of healthcare ethics, is problematic because it (1) fails to sufficiently acknowledge the unique nature of nursing practice; and (2) applies standard ethical frameworks such as principlism to moral problems which tend to alienate (...)
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  44. The Verification Principle: Its Problems and Development.Shane Andre - 1966 - Dissertation, The Claremont Graduate University
  45.  11
    Danger in the Rocks? Thinking through Land Use and Naturally-occurring Asbestos with Structural Ethics.Shane Epting - 2021 - Ethics and the Environment 26 (1):85-104.
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  46.  23
    The limits of environmental remediation protocols for environmental justice cases: lessons from Vieques, Puerto Rico.Shane Epting - 2015 - Contemporary Justice Review: Issues in Criminal, Social, and Restorative Justice 19.
    The United States Federal Government has repeatedly put the people of Vieques, Puerto Rico in harm’s way due to the injurious after-effects of air-to-ground weapons testing. Most of the harm happened during the Navy’s 70 years on the island. Yet, the harm continues today considering that aspects of the cleanup count as continued acts of environmental injustice, viewed within the context of the island’s colonial history. Usually, this harm deals with public health issues, but the remediation protocols do not account (...)
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  47. Spaced learning and the lexical integration of novel words.Shane Lindsay & M. Gareth Gaskell - 2009 - In N. A. Taatgen & H. van Rijn (eds.), Proceedings of the 31st Annual Conference of the Cognitive Science Society. pp. 2517--2522.
     
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  48. Was Hume An Atheist?Shane Andre - 1993 - Hume Studies 19 (1):141-166.
    In lieu of an abstract, here is a brief excerpt of the content:Was Hume An Atheist? Shane Andre Hume's philosophy of religion, as expressed in the Dialogues Concerning Natural Religion, the Natural History of Religion, and sections 10 and 11 ofthe Enquiry ConcerningHuman Understanding,1 invites a number of diverse interpretations. At one extreme are those who see Hume as an "atheist"2 or "anti-theist."3 At the other extreme are those who see Hume as some kind of theist, though not a (...)
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  49.  89
    Automated Vehicles and Transportation Justice.Shane Epting - 2019 - Philosophy and Technology 32 (3):389-403.
    Despite numerous ethical examinations of automated vehicles, philosophers have neglected to address how these technologies will affect vulnerable people. To account for this lacuna, researchers must analyze how driverless cars could hinder or help social justice. In addition to thinking through these aspects, scholars must also pay attention to the extensive moral dimensions of automated vehicles, including how they will affect the public, nonhumans, future generations, and culturally significant artifacts. If planners and engineers undertake this task, then they will have (...)
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  50.  8
    The ancient phonograph.Shane Butler - 2015 - New York: Zone Books.
    A search for traces of the voice before the phonograph, reconstructing a series of ancient soundscapes from Aristotle to Augustine. Long before the invention of musical notation, and long before that of the phonograph, the written word was unrivaled as a medium of the human voice. In The Ancient Phonograph, Shane Butler searches for traces of voices before Edison, reconstructing a series of ancient soundscapes from Aristotle to Augustine. Here the real voices of tragic actors, ambitious orators, and singing (...)
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